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Protein Overview: gi|24348818, gi|...

General Information:
Name(s) found: gi|24374283 [NCBI NR]
gi|24348818 [NCBI NR]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • gi|24374283|ref|NP_718326.1| sensor histidine kinase/response regulator [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24348818|gb|AAN55770.1|AE015713_3 sensor histidine kinase/response regulator [Shewanella oneidensis MR-1] [NCBI NR]
    • Organism: Shewanella oneidensis MR-1
    Length: 1145 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: two-component signal transduction system (phosphorelay) [ISSLink to PubMed article]
    Molecular Function: two-component sensor activity [ISSLink to PubMed article]
    two-component response regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLTLVVAVI AICYVSLLFL LAWGAERWFS GVTKKLQVVI YGLSLAVYCS SWSFLGTVGQ  60
   61 SAKDFWSFIP IFVGPILIFT LGFGMLRKMV LVSKAQNITS VADFIAARYG KSQTLAAIVT 120
  121 LIAMFGIMPY IALQLKAMVF SLNLFQPADD PLNGVTIALL ITALLAIFAI LFGTRKLDAT 180
  181 EHNPGMMLAI AFESLVKLAA FLLVGIVISF GVFDGFGDIW QQASDKSLIH HPNPRIETLM 240
  241 PELLVGMAAF LCMPRQFHVM VVECADESVL SKGRWLFPLY LALFGLFVGP LALAGKLILG 300
  301 DSVAADTYVI NLPLALDHPL LAVIALLGTL SAATGMVIVA VVTISVMVSN EWLVPVVLRT 360
  361 GNIREKNFSQ FSQMLLNARR LAIVIILGLG YGSYLALADS DSLSHLGMLS FGAFAQLAPA 420
  421 LVGGLYWKHG NRAGVFLGLS VGFSLWFYIM LSGMTGNQSP AALMSSNIDL LDAITPNVRD 480
  481 ALTALFANIA CYVLGSIWFR AGVAERIQAS AFVSPGKLKN NASKKSGPIS QQDLLILASR 540
  541 FVSPTRAYES FSRFSTEAVK SDSWHKAATP ELIAHTERLL AGVLGASSAS LVMDSVLQGR 600
  601 DLALDEVFSL VDEASSKIML SQDMLRGAIE HAYEGMSVID SDLNLVAWNY KYVELYQYPE 660
  661 GFLQQGMPIS EVIRFNAARG YCGSGAIEQQ VEKRVQHMRN GTPHTSERQR KDGKVIKIQG 720
  721 NPMPDGGFVM TFTDITQYRQ QERALLEANE TLESRVKERT FELAMLNSEL LEAKAQEEMA 780
  781 NASKSRFLAA VGHDLMQPLN AARLFTASLS QYPNLDREAR TTLSHVNSSL KTAGELLTDL 840
  841 LDISKLDSGM VDVNRRDFAI SELLNGLSVE FEAMAADNQI RFKMIPCSAT VNSDPSLLRR 900
  901 VLQNFLTNAY RYARGGRVLF GCRHRGSELE IQVLDTGCGI DEHETHEIFK EFKRLNNPRS 960
  961 KSVSGLGLGL AIADRISRVL NHGIQVSSQL GRGSVFSITV PLGETVRQPQ VKALPSLLQP1020
 1021 LSGIKVLCID NEEAILAGLE SLLSRWQCEV ICAKDLADAR IKLGLKGVAP DIVLADFHLD1080
 1081 DGQNGVDAMD GIRSLYGKDL PGILITANTR KELVEDVQRR GYHYMAKMIK PAALRALISS1140
 1141 LVKKA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..176] MSA 1.378982 View MSA. No confident structure predictions are available.
    2 View Details [177..360] deduced N/A No confident structure predictions are available.
    3 View Details [361..465] deduced N/A No confident structure predictions are available.
    4 View Details [466..561] deduced N/A No confident structure predictions are available.
    5 View Details [562..755] PSI-BLAST 4.154902 Histidine kinase FixL heme domain
    6 View Details [756..1009] PSI-BLAST 46.154902 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    7 View Details [1010..1145] PSI-BLAST 28.69897 PhoP receiver domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  3.69867247360436 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.34503630083118 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.33645564261978 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.99554083986799 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  2.93659587419536 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.92160783463114 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.91342394807702 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.90751147392211 bayes_pls_golite062009
  • potassium channel activity
    		•  2.89031641462295 bayes_pls_golite062009
  • cation channel activity
    		•  2.78342406299841 bayes_pls_golite062009
  • ion channel activity
    		•  2.75684553022783 bayes_pls_golite062009
  • gated channel activity
    		•  2.70149874833471 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.65172440531618 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.65059750992297 bayes_pls_golite062009
  • channel activity
    		•  2.65059750992297 bayes_pls_golite062009
  • binding
    		•  2.49204215574815 bayes_pls_golite062009
  • transporter activity
    		•  1.90984485953892 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.79183331267186 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.75430109151481 bayes_pls_golite062009
  • signal transducer activity
    		•  1.75430109151481 bayes_pls_golite062009
  • protein binding
    		•  1.73179783495389 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49360338620162 bayes_pls_golite062009
  • DNA binding
    		•  1.20377980878212 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06245381658836 bayes_pls_golite062009
  • two-component response regulator activity
    		•  0.840018959681963 bayes_pls_golite062009
  • transcription factor activity
    		•  0.709293174791556 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.511943063452644 bayes_pls_golite062009
  • transcription factor binding
    		•  0.484038243106157 bayes_pls_golite062009
  • receptor binding
    		•  0.46842316980276 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.456885330585442 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  0.388335970048431 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.3429235361445 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.3429235361445 bayes_pls_golite062009
  • protein kinase activity
    		•  0.293236516800064 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.169353506810019 bayes_pls_golite062009
  • kinase activity
    		•  0.110903778398436 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.0645871948870329 bayes_pls_golite062009
  • receptor activity
    		•  0.0276617751945334 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0029357667432216 bayes_pls_golite062009
    6 No functions predicted.
    7
    Term Confidence Notes
  • two-component response regulator activity
    		•  6.41182973389827 bayes_pls_golite062009
  • signal transducer activity
    		•  5.8299268563449 bayes_pls_golite062009
  • molecular transducer activity
    		•  5.8299268563449 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.23448171655589 bayes_pls_golite062009
  • binding
    		•  1.92400975854452 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  1.60632989169905 bayes_pls_golite062009
  • two-component sensor activity
    		•  1.58303578136745 bayes_pls_golite062009
  • DNA binding
    		•  1.58172125522651 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  1.45748315828993 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43938837585555 bayes_pls_golite062009
  • protein kinase activity
    		•  1.37509495611612 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.08466995707718 bayes_pls_golite062009
  • transcription factor activity
    		•  0.970571914515176 bayes_pls_golite062009
  • kinase activity
    		•  0.9339032594202 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.642205665485028 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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