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Protein Overview: NOG1_YEAST

General Information:
Name(s) found: NOG1_YEAST [Swiss-Prot]
Description(s) found:
  • Nucleolar GTP-binding protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOG1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 647 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSWKDIPT VAPANDLLDI VLNRTQRKTP TVIRPGFKIT RIRAFYMRKV KYTGEGFVEK  60
   61 FEDILKGFPN INDVHPFHRD LMDTLYEKNH YKISLAAISR AKSLVEQVAR DYVRLLKFGQ 120
  121 SLFQCKQLKR AALGRMATIV KKLRDPLAYL EQVRQHIGRL PSIDPNTRTL LICGYPNVGK 180
  181 SSFLRCITKS DVDVQPYAFT TKSLYVGHFD YKYLRFQAID TPGILDRPTE EMNNIEMQSI 240
  241 YAIAHLRSCV LYFMDLSEQC GFTIEAQVKL FHSIKPLFAN KSVMVVINKT DIIRPEDLDE 300
  301 ERAQLLESVK EVPGVEIMTS SCQLEENVME VRNKACEKLL ASRIENKLKS QSRINNVLNK 360
  361 IHVAQPQARD DVKRTPFIPE SVKNLKKYDP EDPNRRKLAR DIEAENGGAG VFNVNLKDKY 420
  421 LLEDDEWKND IMPEILDGKN VYDFLDPEIA AKLQALEEEE EKLENEGFYN SDDEEEIYDG 480
  481 FEASEVDDIK EKAAWIRNRQ KTMIAEARNR KSLKNKAIMP RSKLTKSFGK MEEHMSTLGH 540
  541 DMSALQDKQN RAARKNRYVE RGSDVVFGDQ DALTASTENG VKLRQTDRLL DGVADGSMRS 600
  601 KADRMAKMER RERNRHAKQG ESDRHNAVSL SKHLFSGKRG VGKTDFR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] PSI-BLAST 64.09691 Probable GTPase Der, N-terminal and middle domains; Probable GTPase Der, C-terminal domain
    2 View Details [162..344] PSI-BLAST 64.09691 Probable GTPase Der, N-terminal and middle domains; Probable GTPase Der, C-terminal domain
    3 View Details [345..440] PSI-BLAST 64.09691 Probable GTPase Der, N-terminal and middle domains; Probable GTPase Der, C-terminal domain
    4 View Details [441..647] MSA 2.205961 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.85628130885095 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.78950165917982 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.76996223962376 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.7670079419026 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.61518930814923 bayes_pls_golite062009
  • motor activity
    		•  2.60481158518321 bayes_pls_golite062009
  • transporter activity
    		•  2.36978240084485 bayes_pls_golite062009
  • ATPase activity
    		•  2.26864012421561 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.18065576425044 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.07184330056272 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.80055405467543 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • RNA binding
    		•  1.60613159109369 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.53142082854758 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.52938239070386 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.52887308780164 bayes_pls_golite062009
  • nucleotide binding
    		•  1.52746968836881 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.52494005252804 bayes_pls_golite062009
  • hydrolase activity
    		•  1.44476395406467 bayes_pls_golite062009
    		• 1.44426272235796 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.28029120876672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.25258316272121 bayes_pls_golite062009
  • ATP binding
    		•  1.23942044024113 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.21044170258803 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.19481945569892 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.09373202836575 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • microtubule binding
    		•  0.889065347963087 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86163779946438 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.832861637931298 bayes_pls_golite062009
  • tubulin binding
    		•  0.818881964708536 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.795745617990735 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.771854032852428 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.736988322066518 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.696000326143746 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.677612020025357 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.650964453464311 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.643562482062891 bayes_pls_golite062009
  • kinase activity
    		•  0.641541011250583 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.584453361662212 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.543512707823441 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.39380930211325 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  0.36110509588725 bayes_pls_golite062009
  • protein kinase activity
    		•  0.351308564667977 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • actin binding
    		•  0.269954671912367 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.140475613064199 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.85628130885095 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.78950165917982 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.76996223962376 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.7670079419026 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.61518930814923 bayes_pls_golite062009
  • motor activity
    		•  2.60481158518321 bayes_pls_golite062009
  • transporter activity
    		•  2.36978240084485 bayes_pls_golite062009
  • ATPase activity
    		•  2.26864012421561 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.18065576425044 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.07184330056272 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.80055405467543 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • RNA binding
    		•  1.60613159109369 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.53142082854758 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.52938239070386 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.52887308780164 bayes_pls_golite062009
  • nucleotide binding
    		•  1.52746968836881 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.52494005252804 bayes_pls_golite062009
  • hydrolase activity
    		•  1.44476395406467 bayes_pls_golite062009
    		• 1.44426272235796 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.28029120876672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.25258316272121 bayes_pls_golite062009
  • ATP binding
    		•  1.23942044024113 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.21044170258803 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.19481945569892 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.09373202836575 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • microtubule binding
    		•  0.889065347963087 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86163779946438 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.832861637931298 bayes_pls_golite062009
  • tubulin binding
    		•  0.818881964708536 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.795745617990735 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.771854032852428 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.736988322066518 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.696000326143746 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.677612020025357 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.650964453464311 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.643562482062891 bayes_pls_golite062009
  • kinase activity
    		•  0.641541011250583 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.584453361662212 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.543512707823441 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.39380930211325 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  0.36110509588725 bayes_pls_golite062009
  • protein kinase activity
    		•  0.351308564667977 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • actin binding
    		•  0.269954671912367 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.140475613064199 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle