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Protein Overview: KC12_YEAST

General Information:
Name(s) found: KC12_YEAST [Swiss-Prot]
Description(s) found:
  • Casein kinase I homolog 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCK2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 546 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQVQSPLTA TNSGLAVNNN TMNSQMPNRS NVRLVNGTLP PSLHVSSNLN HNTGNSSASY  60
   61 SGSQSRDDST IVGLHYKIGK KIGEGSFGVL FEGTNMINGL PVAIKFEPRK TEAPQLKDEY 120
  121 RTYKILAGTP GIPQEYYFGQ EGLHNILVID LLGPSLEDLF DWCGRRFSVK TVVQVAVQMI 180
  181 TLIEDLHAHD LIYRDIKPDN FLIGRPGQPD ANKVHLIDFG MAKQYRDPKT KQHIPYREKK 240
  241 SLSGTARYMS INTHLGREQS RRDDMEAMGH VFFYFLRGQL PWQGLKAPNN KQKYEKIGEK 300
  301 KRLTNVYDLA QGLPIQFGRY LEIVRNLSFE ETPDYEGYRM LLLSVLDDLG ETADGQYDWM 360
  361 KLNGGRGWDL SINKKPNLHG YGHPNPPNEK SKRHRSKNHQ YSSPDHHHHY NQQQQQQQAQ 420
  421 AQAQAQAQAK VQQQQLQQAQ AQQQANRYQL QPDDSHYDEE REASKLDPTS YEAYQQQTQQ 480
  481 KYAQQQQKQM QQKSKQFANT GANGQTNKYP YNAQPTANDE QNAKNAAQDR NSNKSSKGFF 540
  541 SKLGCC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118]
    [135..150]    		 PSI-BLAST 1294.0 Casein kinase-1, CK1
    2 View Details [119..134]
    [151..156]
    [181..233]    		 PSI-BLAST 1294.0 Casein kinase-1, CK1
    3 View Details [157..180]
    [234..384]    		 PSI-BLAST 1294.0 Casein kinase-1, CK1
    4 View Details [385..546] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  2.54265774272269 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  2.16831387024372 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16307073947901 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.06086848160606 bayes_pls_golite062009
  • DNA binding
    		•  1.02122968429273 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • growth factor binding
    		•  0.86076618871384 bayes_pls_golite062009
  • transcription factor activity
    		•  0.825932471558326 bayes_pls_golite062009
  • peptidase activity
    		•  0.540289770145252 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.451090007290896 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.41587987561486 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • kinase binding
    		•  0.26752427107238 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.265003282584135 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.26024936404169 bayes_pls_golite062009
  • protein complex binding
    		•  0.239339759110451 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  0.20643152368029 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  0.20643152368029 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.205652638854091 bayes_pls_golite062009
  • receptor binding
    		•  0.197402253061255 bayes_pls_golite062009
  • actin filament binding
    		•  0.10870608219756 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00674998152095019 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle