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Protein Overview: ISW1_YEAST

General Information:
Name(s) found: ISW1_YEAST [Swiss-Prot]
Description(s) found:
  • ISWI chromatin-remodeling complex ATPase ISW1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISW1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1129 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYMLAIANF HFFKFYTRMR KKHENNSCNE KDKDENLFKI ILAIFLQEKK KYDCISSGSI  60
   61 MTASEEYLEN LKPFQVGLPP HDPESNKKRY LLKDANGKKF DLEGTTKRFE HLLSLSGLFK 120
  121 HFIESKAAKD PKFRQVLDVL EENKANGKGK GKHQDVRRRK TEHEEDAELL KEEDSDDDES 180
  181 IEFQFRESPA YVNGQLRPYQ IQGVNWLVSL HKNKIAGILA DEMGLGKTLQ TISFLGYLRY 240
  241 IEKIPGPFLV IAPKSTLNNW LREINRWTPD VNAFILQGDK EERAELIQKK LLGCDFDVVI 300
  301 ASYEIIIREK SPLKKINWEY IIIDEAHRIK NEESMLSQVL REFTSRNRLL ITGTPLQNNL 360
  361 HELWALLNFL LPDIFSDAQD FDDWFSSEST EEDQDKIVKQ LHTVLQPFLL RRIKSDVETS 420
  421 LLPKKELNLY VGMSSMQKKW YKKILEKDLD AVNGSNGSKE SKTRLLNIMM QLRKCCNHPY 480
  481 LFDGAEPGPP YTTDEHLVYN AAKLQVLDKL LKKLKEEGSR VLIFSQMSRL LDILEDYCYF 540
  541 RNYEYCRIDG STAHEDRIQA IDDYNAPDSK KFVFLLTTRA GGLGINLTSA DVVVLYDSDW 600
  601 NPQADLQAMD RAHRIGQKKQ VKVFRLVTDN SVEEKILERA TQKLRLDQLV IQQNRTSLKK 660
  661 KENKADSKDA LLSMIQHGAA DVFKSGTSTG SAGTPEPGSG EKGDDIDLDE LLLKSENKTK 720
  721 SLNAKYETLG LDDLQKFNQD SAYEWNGQDF KKKIQRDIIS PLLLNPTKRE RKENYSIDNY 780
  781 YKDVLNTGRS STPSHPRMPK PHVFHSHQLQ PPQLKVLYEK ERMWTAKKTG YVPTMDDVKA 840
  841 AYGDISDEEE KKQKLELLKL SVNNSQPLTE EEEKMKADWE SEGFTNWNKL EFRKFITVSG 900
  901 KYGRNSIQAI ARELAPGKTL EEVRAYAKAF WSNIERIEDY EKYLKIIENE EEKIKRVKMQ 960
  961 QEALRRKLSE YKNPFFDLKL KHPPSSNNKR TYSEEEDRFI LLMLFKYGLD RDDVYELVRD1020
 1021 EIRDCPLFEL DFYFRSRTPV ELARRGNTLL QCLEKEFNAG IVLDDATKDR MKKEDENGKR1080
 1081 IREEFADQTA NEKENVDGVE SKKAKIEDTS NVGTEQLVAE KIPENETTH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] MSA 1.231996 View MSA. Confident ab initio structure predictions are available.
    2 View Details [123..375] PSI-BLAST 4.69897 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    3 View Details [376..433] deduced N/A No confident structure predictions are available.
    4 View Details [434..618] PSI-BLAST 11.154902 Putative DEAD box RNA helicase
    5 View Details [619..990] MSA 3.688996 View MSA. No confident structure predictions are available.
    6 View Details [991..1129] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  3.1726526166851 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.23094623498843 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.21658213854831 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.21652144153182 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.21571071905795 bayes_pls_golite062009
  • nucleotide binding
    		•  1.20347573865566 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.11383295816593 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  1.05990253628867 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  1.05990253628867 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription activator activity
    		•  0.889929694023098 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.862685397469217 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.729056749897011 bayes_pls_golite062009
  • steroid hormone receptor binding
    		•  0.647625526012423 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.620212706423176 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.57378485697982 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.543891899378373 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.49811753387851 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.49000746592281 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.388587892299301 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.372638007722845 bayes_pls_golite062009
  • GTP binding
    		•  0.364508542344128 bayes_pls_golite062009
  • hormone receptor binding
    		•  0.351501100511918 bayes_pls_golite062009
  • centromeric DNA binding
    		•  0.322818640526369 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.24825301806267 bayes_pls_golite062009
  • nuclear hormone receptor binding
    		•  0.246160342138071 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.243902356228423 bayes_pls_golite062009
  • GTPase activity
    		•  0.234351968078991 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.18426050934025 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.14606996093053 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.133017653323467 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.13050483816765 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle