| Protein: | lola-PP |
| Organism: | Drosophila melanogaster |
| Length: | 963 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lola-PP.
| Description | E-value | Query Range |
Subject Range |
|
|
580.0 | [0..293] | [962..104] |
|
Region A: Residues: [1-196] |
1 11 21 31 41 51
| | | | | |
1 MDDDQQFCLR WNNHQSTLIS VFDTLLENET LVDCTLAAEG KFLKAHKVVL SACSPYFATL 60
61 LQEQYDKHPI FILKDVKYQE LRAMMDYMYR GEVNISQDQL AALLKAAESL QIKGLSDNRT 120
121 GGGVAPKPES SGHHRGGKLS GAYTLEQTKR ARLATGGAMD TSGDVSGSRE GSSSPSRRRR 180
181 KVRRRSMEND AHDNSN
|
| Detection Method: |  |
| Confidence: | 33.30103 |
| Match: | 1r28A |
| Description: | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.03732153795237 | bayes_pls_golite062009 |
| DNA binding | 3.50992893425527 | bayes_pls_golite062009 |
| nucleic acid binding | 3.39650042677839 | bayes_pls_golite062009 |
| transcription repressor activity | 3.34221155527033 | bayes_pls_golite062009 |
| transcription factor activity | 2.77967244868934 | bayes_pls_golite062009 |
| binding | 2.73171412378045 | bayes_pls_golite062009 |
| protein binding | 2.43603601331034 | bayes_pls_golite062009 |
| gated channel activity | 2.31670938272069 | bayes_pls_golite062009 |
| cation channel activity | 2.29487032939987 | bayes_pls_golite062009 |
| ion channel activity | 2.26817638058015 | bayes_pls_golite062009 |
| potassium channel activity | 1.44385468589872 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 1.43775565332764 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.43014386864286 | bayes_pls_golite062009 |
| channel activity | 1.41924822300643 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 1.41924822300643 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 1.41843723045096 | bayes_pls_golite062009 |
| substrate-specific channel activity | 1.4152854884651 | bayes_pls_golite062009 |
| voltage-gated channel activity | 1.40892835925684 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.3794923488776 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 1.37848954483947 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.36107960937272 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.34347609298791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.32720756453806 | bayes_pls_golite062009 |
| transcription activator activity | 1.3134483946218 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.2813343017365 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.933012980583336 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.69971422997918 | bayes_pls_golite062009 |
| transporter activity | 0.14391700968389 | bayes_pls_golite062009 |
| catalytic activity | 0.112500532859479 | bayes_pls_golite062009 |
| chromatin binding | 0.0908724449159477 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.0733959562343498 | bayes_pls_golite062009 |
|
Region A: Residues: [197-372] |
1 11 21 31 41 51
| | | | | |
1 SSVLQAAASN QSILQQTGAG LAVSALVTTQ LSSGPAAGTS SQASSTQQQQ PLTSTNVTKK 60
61 TESAKLTSST AAPASGASAS AAVQQAHLHQ QQAQTTSDAI NTENVQAQSQ GGAQGVQGDD 120
121 EDIDEGSAVG GPNSATGPNP ASASASAVHA GVVVKQLASV VDKSSSNHKH KIKDNS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [373-451] |
1 11 21 31 41 51
| | | | | |
1 VSSVGSEMVI EPKAEYDDDA HDENVEDLTL DEEDMTMEEL DQTAGTSQGG EGSSQTYATW 60
61 QHDRSQDELG LMAQDAQQR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [452-517] |
1 11 21 31 41 51
| | | | | |
1 DPQDEAGQNE GGESRIRVRN WLMLADKSII GKSSDEPSDK LTQSKKSLIS DAKTTNKTST 60
61 PIRPKV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [518-629] |
1 11 21 31 41 51
| | | | | |
1 STTTTSTSTA AAAAAAATIA AKQAAAAIAS SNINNNNSSL TQTVTQTVTR IGSIGRTTIA 60
61 CITPANNGNK SSSSNCNVDA ASAAALAAAG VELDSIDDTM TEVIVKIENP ES
|
| Detection Method: | |
| Confidence: | 3.69897 |
| Match: | 2dlkA |
| Description: | No description for 2dlkA was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 4.70988788192472 | bayes_pls_golite062009 |
| nucleic acid binding | 4.58713908116892 | bayes_pls_golite062009 |
| DNA binding | 4.56219307357342 | bayes_pls_golite062009 |
| transcription activator activity | 3.52873291636993 | bayes_pls_golite062009 |
| transcription factor activity | 3.50954949535763 | bayes_pls_golite062009 |
| transcription repressor activity | 3.27542149084008 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.22082323675675 | bayes_pls_golite062009 |
| binding | 3.10743787485868 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.53101891154822 | bayes_pls_golite062009 |
| chromatin binding | 2.18464662431232 | bayes_pls_golite062009 |
| protein binding | 2.05530362750351 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.63161912031789 | bayes_pls_golite062009 |
| transcription factor binding | 1.39608963544799 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.34049786451995 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.77874411480713 | bayes_pls_golite062009 |
| catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
|
Region A: Residues: [630-765] |
1 11 21 31 41 51
| | | | | |
1 MPLNDDEDDA VCNEAIEDEN TFDYDLKLGS PLSWTYDAVK IENEEFEDSY LMDNDDDDDD 60
61 LLTTAAATQK HAKQSNEKQM AGSMVAGAGS GGAVKKIVLS AQQQQQLLEQ QQHLQHLQLQ 120
121 PTSQSLQIKL PAIPAT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [766-963] |
1 11 21 31 41 51
| | | | | |
1 ITTISAPKQM MSGAGTSGSL TPNNNCTLMS NKLGLPVKGQ NLDLHWSHSD DNRYRVLVQN 60
61 KRTRKESLEH SADMIYNADI EKPWVCRNCN RTYKWKNSLK CHLKNECGLP PRYFCSKMCG 120
121 YATNVHSNLK RHLNTKCRDR EKDADDEKKP GSASGNMPVV VGVGNGTAVP VSSSNNNNNG 180
181 GGSSTSSTYT LVFQNDSA
|
| Detection Method: | |
| Confidence: | 52.09691 |
| Match: | 2i13A |
| Description: | No description for 2i13A was found. |
