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View Structure Prediction Details

Protein: cyp-29A3
Organism: Caenorhabditis elegans
Length: 503 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cyp-29A3.

Description E-value Query
Range
Subject
Range
gi|115496944, gi... - gi|94574282|gb|AAI16042.1| Cytochrome P450, family 2, subfamily C, polypeptide 18 [Bos taurus], gi|1...
380.0 [0..26] [501..20]

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Predicted Domain #1
Region A:
Residues: [1-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLILPCLLI ILLLFIVSFW KIMKNILKYR KYDDLLPGPP AHPIFGNTKT FSNKTTEEIF  60
   61 QALRDLFSEA VEKGQSLIRH RILGTFYVWP LDGKTVSKIL ESTTELDKGG PYEFFNDWLG 120
  121 GGTLLEGYGE RWRSHRKMLT PTFHFAKLEG YFEVFNTESR VVVDCLDKFA KSGETVDLFP 180
  181 FFKRCTLDTI CKTAMGAKVD AQLQNSHPYI TAIEQALQLG VLYAMNPHHQ IPAIYWALGH 240
  241 QKKKDEYFNI MKTFTRNVIA ERRTARESGE VEKETSKRNM NFLDILLSNE ESSVLSPEDL 300
  301 RQEVDTFMFA GHDTTTTSVS WVCWNLAHHP DIQQNVYEEI VSVFGEDPNE DVTTEGIKKL 360
  361 EYTERMLKES KRICPTVPAV LRQLISDMEI GGVLIPAGAN VAIAPMAIHK NANIYQNPDI 420
  421 FDPDRFLPEE TAKRHAYDFI PFSAGLRNCI GQKFAQLNEK VMVIHLLKNF KIEPMGGYYS 480
  481 TKQVFEPVGK PSNGIPVRLV RRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.045757
Match: 1tqnA
Description: Crystal Structure of Human Microsomal P450 3A4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 6.3313834755701 bayes_pls_golite062009
monooxygenase activity 5.57229509004705 bayes_pls_golite062009
steroid hydroxylase activity 5.04794778387361 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.68151610133025 bayes_pls_golite062009
demethylase activity 3.40807632433846 bayes_pls_golite062009
fluorene oxygenase activity 3.16634614522939 bayes_pls_golite062009
sterol 14-demethylase activity 2.94610675710811 bayes_pls_golite062009
oxygen binding 2.77495508953933 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2.56821164444595 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 2.36480328243514 bayes_pls_golite062009
oxidoreductase activity 2.35847923992364 bayes_pls_golite062009
steroid 7-alpha-hydroxylase activity 2.21042366294727 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 2.15105968497418 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 2.0071742914584 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 1.90796041033974 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1.46109575978397 bayes_pls_golite062009
retinoid binding 1.16961058051431 bayes_pls_golite062009
binding 1.0881336564542 bayes_pls_golite062009
isoprenoid binding 1.04601505165702 bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity 0.89030345144459 bayes_pls_golite062009
flavonoid 3'-monooxygenase activity 0.89030345144459 bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity 0.88385909514903 bayes_pls_golite062009
retinoic acid binding 0.851040588981921 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
cholesterol monooxygenase (side-chain-cleaving) activity 0.276594551871869 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle