| Protein: | mcm-7 |
| Organism: | Caenorhabditis elegans |
| Length: | 730 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mcm-7.
| Description | E-value | Query Range |
Subject Range |
|
|
532.0 | [0..1] | [730..1] |
|
Region A: Residues: [1-63] |
1 11 21 31 41 51
| | | | | |
1 MKTTTYNTDW AAEKTKIRSF FDEYYVDNED GSGKAFPYRD QVFEIARRDK QAIVVNVDHI 60
61 KES
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [64-272] |
1 11 21 31 41 51
| | | | | |
1 DIPDALELSE AITSNTKRYE VLFKDTISDM IQDYLGDKQA PVIDALDAYM FQRLHMDRNE 60
61 GAANEEVSLQ DKRKKYPPQL LQRFEVYFTT DDAAHETCVR NIKATEIGHL VSMKGVVIRA 120
121 TEVKPCVEVM TYTCDTCAAE VYQPVKGMQF TPPVNCPNKE CVEAKANGRL HMQLRGSKFV 180
181 KFQELKIQEL SEQVPVGSIP RTMTVHVYG
|
| Detection Method: | |
| Confidence: | 42.522879 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telomeric DNA binding | 4.81350293592083 | bayes_pls_golite062009 |
| telomerase inhibitor activity | 4.48082903165152 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 4.34033743483519 | bayes_pls_golite062009 |
| nucleic acid binding | 4.29626483284963 | bayes_pls_golite062009 |
| DNA binding | 3.71771169141041 | bayes_pls_golite062009 |
| structural constituent of ribosome | 3.51998515668903 | bayes_pls_golite062009 |
| structure-specific DNA binding | 3.48139490984491 | bayes_pls_golite062009 |
| single-stranded DNA binding | 3.43027351695641 | bayes_pls_golite062009 |
| structural molecule activity | 3.29857127235306 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| transcription regulator activity | 2.10110937001387 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.9581702424972 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.84819558112187 | bayes_pls_golite062009 |
| translation regulator activity | 1.46320772716954 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 1.40718318783582 | bayes_pls_golite062009 |
| transcription repressor activity | 1.30343463892105 | bayes_pls_golite062009 |
| translation initiation factor activity | 1.27539679024898 | bayes_pls_golite062009 |
| transcription activator activity | 1.24141936405635 | bayes_pls_golite062009 |
| protein binding | 1.20309946451799 | bayes_pls_golite062009 |
| RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| ribonuclease activity | 1.19236946227657 | bayes_pls_golite062009 |
| transcription factor activity | 1.14242112812892 | bayes_pls_golite062009 |
| DNA helicase activity | 1.12203697857261 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.638831894247026 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 0.474251377131502 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 0.47336621289748 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 0.47336621289748 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.325774164899685 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.314881439089948 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.311535572386606 | bayes_pls_golite062009 |
| exonuclease activity | 0.28313884527829 | bayes_pls_golite062009 |
| RNA binding | 0.18502033889261 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 0.125256208482441 | bayes_pls_golite062009 |
| exoribonuclease activity | 0.109774918833391 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.0954216620147701 | bayes_pls_golite062009 |
| DEAD/H-box RNA helicase binding | 0.0627405398613412 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0179535526984695 | bayes_pls_golite062009 |
| helicase activity | 0.0121541775159524 | bayes_pls_golite062009 |
|
Region A: Residues: [273-352] |
1 11 21 31 41 51
| | | | | |
1 EMTRKCNTGN VVHVSGVFLP IMQSGFRPTG GLVADTYLEA HYINNLDDNP TFNGVQSAEL 60
61 EVLRRKGDNY ETLAASIAPE
|
| Detection Method: | |
| Confidence: | 1.62 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [353-582] |
1 11 21 31 41 51
| | | | | |
1 IFGHVDVKKC LLMALVGGND NSSNGMKIRG CINVLMMGDP GVAKSQLLGY VNRLAPRSQY 60
61 TTGRGSSGVG LTAAVMKDPV TGEMSLEGGA LVLADGGICC IDEFDKMMDH DRTAIHEVME 120
121 QQTISIAKAG IMTTLNARTA IIAAANPAYG RYNPNRSIEQ NVDLPAALLS RFDLILLMQD 180
181 KADRENDKIL AEHITYVHQH GCHPNREKKD LISLETLREY ISLCKTYTPT
|
| Detection Method: | |
| Confidence: | 9.0 |
| Match: | 1lv7A |
| Description: | AAA domain of cell division protein FtsH |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.0142766759353 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.53142082854758 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.52938239070386 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.52887308780164 | bayes_pls_golite062009 |
| nucleotide binding | 1.52746968836881 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| microtubule motor activity | 1.35938517416356 | bayes_pls_golite062009 |
| ATP binding | 1.23942044024113 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.21044170258803 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.20315703345493 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.19481945569892 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.05408274676326 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.8469248456592 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.700780808446722 | bayes_pls_golite062009 |
| kinase activity | 0.641541011250583 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.584453361662212 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.406600732518248 | bayes_pls_golite062009 |
| protein kinase activity | 0.351308564667977 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| RNA helicase activity | 0.18426050934025 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.156278588350022 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.14606996093053 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.13366911641814 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.13050483816765 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.0223627159838333 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [583-730] |
1 11 21 31 41 51
| | | | | |
1 VDPALRERIV EAYVEMRRDA RYSSDPTFVS PRMILGIVRM ATARAKLRLS TIVDESDVEE 60
61 ALRLMQFAKD SLRPEQNKIE KRMAPVDAAF AVLRELYHAD NAPIAISNAI QRCARKGISE 120
121 VALKKCLDQY TANGLLVMDR QNIVFAMN
|
| Detection Method: | |
| Confidence: | 37.0 |
| Match: | 2r44A |
| Description: | No description for 2r44A was found. |
