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View Structure Prediction Details

Protein: SPBC1685.08
Organism: Schizosaccharomyces pombe
Length: 424 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1685.08.

Description E-value Query
Range
Subject
Range
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
151.0 [0..7] [370..107]
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
143.0 [0..1] [403..692]
gi|24020878, gi|... - gi|50979202|ref|NP_001003352.1| neurofilament, heavy polypeptide 200kDa [Canis lupus familiaris], gi...
139.0 [0..3] [405..571]
gi|6469847 - gi|6469847|gb|AAF13456.1| unknown [Streptococcus pneumoniae]
gi|6469847 - gi|6469847|gb|AAF13456.1| unknown [Streptococcus pneumoniae]
136.0 [0..9] [370..109]
gi|25509405, gi|... - gi|8163644|gb|AAF73779.1| surface protein PspC [Streptococcus pneumoniae], pir||H98120 choline bindi...
gi|15459699, gi|... - gi|15904036|ref|NP_359586.1| choline binding protein A [Streptococcus pneumoniae R6], gi|15459699|gb...
gi|116515359, gi... - gi|8163644|gb|AAF73779.1|AF154012_1 surface protein PspC [Streptococcus pneumoniae], gi|116515359|re...
136.0 [0..9] [370..109]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSNSTPANE EKEEESEKIQ KSPVDTPHTP NGSVSDNEEN ETSSTGEVTR CVCGIVESDD  60
   61 EASDGGLYIQ CDQCSVWQHG NCVGFADESE VPEVYYCEIC HPEFHKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1wemA
Description: Solution structure of PHD domain in death inducer-obliterator 1(DIO-1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein deacetylase activity 7.50578521120904 bayes_pls_golite062009
histone deacetylase activity 7.35162059871663 bayes_pls_golite062009
deacetylase activity 6.55925777139018 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5.24378850198774 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4.39452339322141 bayes_pls_golite062009
methylated histone residue binding 4.19057851212315 bayes_pls_golite062009
histone acetyltransferase activity 3.20023500652896 bayes_pls_golite062009
lysine N-acetyltransferase activity 3.20023500652896 bayes_pls_golite062009
histone binding 3.01402804224903 bayes_pls_golite062009
binding 2.93415748500038 bayes_pls_golite062009
transcription regulator activity 2.89424169822343 bayes_pls_golite062009
DNA binding 2.67786232715949 bayes_pls_golite062009
nucleic acid binding 2.6327300364647 bayes_pls_golite062009
nucleosome binding 1.69494047037058 bayes_pls_golite062009
transcription factor activity 1.62385700361588 bayes_pls_golite062009
protein binding 1.42349040268084 bayes_pls_golite062009
1.38236406424542 bayes_pls_golite062009
N-acetyltransferase activity 1.19037129579681 bayes_pls_golite062009
N-acyltransferase activity 0.873079221910902 bayes_pls_golite062009
transcription activator activity 0.739132967687069 bayes_pls_golite062009
transcription repressor activity 0.507152521861549 bayes_pls_golite062009
histone methyltransferase activity 0.476506467104495 bayes_pls_golite062009
protein kinase activity 0.405766438875014 bayes_pls_golite062009
acetyltransferase activity 0.39905022319963 bayes_pls_golite062009
chromatin binding 0.39425178848458 bayes_pls_golite062009
cytoskeletal protein binding 0.327424740985033 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.199823005659601 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.14235705491362 bayes_pls_golite062009
kinase activity 0.12732151557306 bayes_pls_golite062009
0.0927457062201698 bayes_pls_golite062009
sequence-specific DNA binding 0.0725773086825168 bayes_pls_golite062009
transcription factor binding 0.0538806851320555 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 0.0490968711985191 bayes_pls_golite062009
histone acetyl-lysine binding 0.0410393640547611 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [108-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQRGRGAKQS KYLGNGKPIE ASQTEESSST PPSPATKKSS KQRLTMNSRD AALDYEEYLA  60
   61 IAKEKSLIPR RSRGRTSSKS LSPPAPQDES QGTEINLKQK IE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [210-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EENDEILEDS KESKDENEEN KETSTTNVAE TDAPEEETVD TVEEIADEEK HSVKEESGEA  60
   61 SPQSSQQSTI TSISTTTRST RKAKREAAAE DKADLPAAVA PKPSKTRKVG GRRGKSSSND 120
  121 NHRIPQLHPD GTFVETITKP KGLHSRITMT EMRRRVASML EYIGHIQVEM AAQSAGNQSS 180
  181 TKSSKEGPEE EKETLRMVDN LTRDLLHWEQ RFSRT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle