YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC1861.07
Organism:	Schizosaccharomyces pombe
Length:	97 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1861.07.

Description	E-value	Query Range	Subject Range
gi\|114601677 - gi\|114601677\|ref\|XP_001166095.1\| PREDICTED: S-phase kinase-associated protein 1A isoform 2 [Pan trog...	134.0	[0..6]	[96..4]
gi\|73985712, gi\|... - gi\|73985714\|ref\|XP_863918.1\| PREDICTED: similar to S-phase kinase-associated protein 1A isoform a is...	134.0	[0..6]	[96..4]
gi\|74177667 - gi\|74177667\|dbj\|BAE38934.1\| unnamed protein product [Mus musculus]	133.0	[0..4]	[96..2]
gi\|221221226, gi... - gi\|221221806\|gb\|ACM09564.1\| S-phase kinase-associated protein 1 [Salmo salar], gi\|221221226\|gb\|ACM09... gi\|225704136, gi... - gi\|225704136\|gb\|ACO07914.1\| S-phase kinase-associated protein 1A [Oncorhynchus mykiss], gi\|225703580... SKP1_RAT - S-phase kinase-associated protein 1 OS=Rattus norvegicus GN=Skp1 PE=1 SV=3 gi\|229367476 - gi\|229367476\|gb\|ACQ58718.1\| S-phase kinase-associated protein 1 [Anoplopoma fimbria] SKP1_MOUSE - S-phase kinase-associated protein 1 OS=Mus musculus GN=Skp1 PE=1 SV=3	133.0	[0..4]	[96..2]
gi\|19344004, gi\|... - gi\|25777711\|ref\|NP_008861.2\| S-phase kinase-associated protein 1 isoform a [Homo sapiens], gi\|193440... gi\|123981218, gi... - gi\|123996055\|gb\|ABM85629.1\| S-phase kinase-associated protein 1A (p19A) [synthetic construct], gi\|12... gi\|114601697 - gi\|114601697\|ref\|XP_001166167.1\| PREDICTED: S-phase kinase-associated protein 1A isoform 4 [Pan trog...	133.0	[0..6]	[96..4]
gi\|109122438 - gi\|109122438\|ref\|XP_001094634.1\| PREDICTED: similar to S-phase kinase-associated protein 1A isoform ...	132.0	[0..6]	[96..4]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKEYVRLIS GDGFVFILEK EIACLSGTIR AILNEGIFSE AQKNECTFPD IRATLLEKVC  60
   61 EYLHYNYRYK NQLDIPKFDI PPEMVLELLV TAEYLEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.045757
Match:	1vcbB
Description:	Elongin C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription elongation regulator activity	7.53002625989446	bayes_pls_golite062009
ubiquitin-protein ligase activity	6.78934422958647	bayes_pls_golite062009
small conjugating protein ligase activity	6.52079977531395	bayes_pls_golite062009
acid-amino acid ligase activity	5.78412146341235	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	4.95822114853319	bayes_pls_golite062009
transcription regulator activity	4.03732153795237	bayes_pls_golite062009
DNA binding	3.26500171477452	bayes_pls_golite062009
binding	3.25487903155187	bayes_pls_golite062009
nucleic acid binding	2.97922606919142	bayes_pls_golite062009
transcription factor activity	2.57500386784378	bayes_pls_golite062009
cation channel activity	1.92125363534463	bayes_pls_golite062009
gated channel activity	1.88630914691725	bayes_pls_golite062009
ion channel activity	1.7702699395278	bayes_pls_golite062009
ligase activity	1.75579073151181	bayes_pls_golite062009
transcription repressor activity	1.71028791830657	bayes_pls_golite062009
substrate-specific channel activity	1.61397056596603	bayes_pls_golite062009
passive transmembrane transporter activity	1.5869038359926	bayes_pls_golite062009
channel activity	1.5869038359926	bayes_pls_golite062009
voltage-gated cation channel activity	1.43888140814503	bayes_pls_golite062009
protein binding	1.40851309733871	bayes_pls_golite062009
voltage-gated channel activity	1.29999209316376	bayes_pls_golite062009
voltage-gated ion channel activity	1.26333187190685	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.933012980583336	bayes_pls_golite062009
structure-specific DNA binding	0.784594789263781	bayes_pls_golite062009
voltage-gated potassium channel activity	0.318894446962849	bayes_pls_golite062009
potassium channel activity	0.288501096353748	bayes_pls_golite062009
sequence-specific DNA binding	0.189580737604762	bayes_pls_golite062009
catalytic activity	0.112500532859479	bayes_pls_golite062009
double-stranded DNA binding	0.033499769837058	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: