YRC Public Data Repository - Protein Structure Prediction

Protein:	sar1
Organism:	Schizosaccharomyces pombe
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sar1.

Description	E-value	Query Range	Subject Range
gi\|34909214, gi\|... - gi\|34909214\|ref\|NP_915954.1\| putative ADP-ribosylation factor [Oryza sativa (japonica cultivar-group...	199.0	[0..2]	[190..177]
gi\|49259163, gi\|... - gi\|49259164\|pdb\|1SVS\|A Chain A, Structure Of The K180p Mutant Of Gi Alpha Subunit Bound To Gppnhp, g...	197.0	[0..6]	[190..130]
gi\|73981983 - gi\|73981983\|ref\|XP_535402.2\| PREDICTED: similar to guanine nucleotide binding protein (G protein), a...	197.0	[0..6]	[190..178]
gi\|109067667 - gi\|109067667\|ref\|XP_001108656.1\| PREDICTED: similar to guanine nucleotide binding protein, alpha inh...	196.0	[0..6]	[190..137]
gi\|163130 - gi\|163130\|gb\|AAA30561.1\| p-alpha-h subunit	195.0	[0..6]	[190..26]
gi\|114662614 - gi\|114662614\|ref\|XP_510976.2\| PREDICTED: guanine nucleotide binding protein, alpha activating polype...	195.0	[0..3]	[190..312]
gi\|152149209, gi... - gi\|21465864\|pdb\|1KJY\|C Chain C, Crystal Structure Of Human G[alpha]i1 Bound To The Goloco Motif Of R...	195.0	[0..6]	[190..102]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIINWFYDA LAMLGLVNKH AKMLFLGLDN AGKTTLLHML KNDRLAVMQP TLHPTSEELA  60
   61 IGNVRFTTFD LGGHQQARRL WRDYFPEVNG IVYLVDCCDF ERLSESKAEL DALLAMEELA 120
  121 RVPFLILGNK IDAPGAISED ELKAALGLYQ TTGKGVSKPV PGIRPIEVFM CSVVLRQGYG 180
  181 EGFKWLAQYV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.154902
Match:	1m2oB
Description:	SAR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
motor activity	3.3674051903467	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
microtubule motor activity	2.9037759597776	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
microfilament motor activity	2.51786963027655	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
cytoskeletal protein binding	2.4101693596493	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
actin binding	2.2973522188675	bayes_pls_golite062009
structural constituent of muscle	2.27871582090443	bayes_pls_golite062009
nucleic acid binding	2.09956015274464	bayes_pls_golite062009
transcription regulator activity	2.09345198747025	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
guanyl nucleotide binding	1.89320355239381	bayes_pls_golite062009
guanyl ribonucleotide binding	1.88721318481223	bayes_pls_golite062009
GTP binding	1.87900088157196	bayes_pls_golite062009
DNA binding	1.87765278833074	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
GTPase activity	1.6309422514633	bayes_pls_golite062009
tubulin binding	1.62788446088451	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
signal recognition particle binding	1.46975774710831	bayes_pls_golite062009
microtubule binding	1.44471873069962	bayes_pls_golite062009
actin filament binding	1.28204719195916	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
RNA helicase activity	1.02424782546779	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATP binding	0.98146619596929	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
RNA-dependent ATPase activity	0.95986988363392	bayes_pls_golite062009
adenyl ribonucleotide binding	0.949788783884952	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.94128341275411	bayes_pls_golite062009
adenyl nucleotide binding	0.931486373329219	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
actin-dependent ATPase activity	0.92105578610354	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
kinase activity	0.691112783105676	bayes_pls_golite062009
molecular transducer activity	0.683309012097319	bayes_pls_golite062009
signal transducer activity	0.683309012097319	bayes_pls_golite062009
transcription factor activity	0.682439846757997	bayes_pls_golite062009
transmembrane receptor activity	0.661834961742057	bayes_pls_golite062009
receptor activity	0.633514002718998	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
ribonucleoprotein binding	0.53788302029845	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.499834566483656	bayes_pls_golite062009
drug transmembrane transporter activity	0.38711726712063	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.305627755818843	bayes_pls_golite062009
plus-end-directed microtubule motor activity	0.267845390391521	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.213018989352421	bayes_pls_golite062009
structural constituent of ribosome	0.208665086324262	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0430764033739892	bayes_pls_golite062009
protein kinase activity	0.0364322017534667	bayes_pls_golite062009
structural constituent of cytoskeleton	0.0111338193708552	bayes_pls_golite062009
dynein binding	0.00615444901942652	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: