| Protein: | mcm3 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 879 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mcm3.
| Description | E-value | Query Range |
Subject Range |
|
|
548.0 | [0..2] | [879..4] |
|
|
546.0 | [0..2] | [879..112] |
|
|
544.0 | [0..2] | [879..4] |
|
|
537.0 | [0..2] | [879..4] |
|
|
536.0 | [0..2] | [879..4] |
|
|
536.0 | [0..2] | [879..4] |
|
Region A: Residues: [1-317] |
1 11 21 31 41 51
| | | | | |
1 MTELLADEVF KDRVRIFQEY LEHDTDDANV TLYQEAILRM LNMGQRRLIV NIDELRDYNR 60
61 ELADGVLLKP LEYVEPFDEA LRNVVSTLID PVVHKDLKDK LFYVGFRGSF GDHHVNPRTL 120
121 RAMHLNKMIS LEGIVTRCSF VRPKVIKSVH YCEATKRHHF KQYADATMNG GLSFQSTVYP 180
181 TQDENGNPLS IEFGFSTFRD HQSISLQEMP ERAPPGQLPR SIDILLDDDL VDTVKPGDRV 240
241 NIVGQYRSMG SKTSGNTSAT FRTVLLANNV VLLGNKPGLG NVGGGALDIT DADIRNINKL 300
301 ARKKNVFELL STSLAPS
|
| Detection Method: |  |
| Confidence: | 40.0 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 3.99127970564994 | bayes_pls_golite062009 |
| DNA binding | 3.53568546959418 | bayes_pls_golite062009 |
| structure-specific DNA binding | 3.06066809614422 | bayes_pls_golite062009 |
| single-stranded DNA binding | 3.0183551365402 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| telomerase inhibitor activity | 2.77979101622935 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.51555240517937 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 2.42617682290608 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.13063800565247 | bayes_pls_golite062009 |
| structural molecule activity | 1.9177190829469 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.84819558112187 | bayes_pls_golite062009 |
| transcription regulator activity | 1.84350127337404 | bayes_pls_golite062009 |
| DNA helicase activity | 1.12203697857261 | bayes_pls_golite062009 |
| transcription factor activity | 0.952569279670437 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.85691075793641 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 0.79554655100991 | bayes_pls_golite062009 |
| RNA polymerase activity | 0.79554655100991 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.638831894247026 | bayes_pls_golite062009 |
| ribonuclease activity | 0.62994126331969 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.325774164899685 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.31769813397725 | bayes_pls_golite062009 |
| translation regulator activity | 0.31332179848255 | bayes_pls_golite062009 |
| exonuclease activity | 0.28313884527829 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.263197317040851 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.2080607201312 | bayes_pls_golite062009 |
| protein binding | 0.152645195799531 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.0954216620147701 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0179535526984695 | bayes_pls_golite062009 |
| helicase activity | 0.0121541775159524 | bayes_pls_golite062009 |
|
Region A: Residues: [318-806] |
1 11 21 31 41 51
| | | | | |
1 IYGYEYVKQA ILLLLLGGTE KNLTNGTHIR GDINILMVGD PSTAKSQLLR FVLNTAPLAI 60
61 ATTGRGSSGV GLTAAVTTDK ETGERRLEAG AMVLADRGVV CIDEFDKMSD IDRVAIHEVM 120
121 EQQTVTIAKA GIHTSLNARC SVIAAANPIY GQYDIRKDPH QNIALPDSML SRFDLLFIVT 180
181 DDIDDKKDRA LSEHVLRMHR YLPPGVEPGT PVRDSLNSVL NVGATNAAGV STENVEQEVE 240
241 TPVWETFSSL LHANARTKKK ELLNINFVRK YIQYAKSRIH PILNQATAEY ITNIYCGLRN 300
301 DDLQGNQRRT SPLTARTLET LIRLSTAHAK ARLSSVVEVK DAKAAEKILR YALFREVVKP 360
361 KRKKHKKQRL EAGEEFDSED DNSDDMDIEE SEEEMDTNMV IDSGSRRVTR SQNATSQSQE 420
421 SGSEIGSSIA GTAGSYNVGT SNTQLSWPST HSTLPATSRE LASSDRNINT GTSVASEVSA 480
481 SVSEQSTVS
|
| Detection Method: | |
| Confidence: | 50.522879 |
| Match: | 2ce7A |
| Description: | EDTA treated |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| nucleic acid binding | 2.21184938313192 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 1.94055378599526 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| transcription regulator activity | 1.83584389083042 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.782430219754236 | bayes_pls_golite062009 |
| transcription factor activity | 0.697256579145077 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.6071273686445 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| RNA helicase activity | 0.34746349346164 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.30832907234141 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.29532978396745 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.26252931460003 | bayes_pls_golite062009 |
| exodeoxyribonuclease V activity | 0.185603938981231 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.089234257580272 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [807-879] |
1 11 21 31 41 51
| | | | | |
1 LPREKMSVFM ARLASLTKSE LFSEECASLE DVLESINNIE DDVGFSREEA IVALKEMDAQ 60
61 NKIMFSDNVV YRI
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
