| Protein: | r-PA, FBpp030914... |
| Organism: | Drosophila melanogaster |
| Length: | 2224 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for r-PA, FBpp030914....
| Description | E-value | Query Range |
Subject Range |
|
|
2319.0 | [0..2] | [2218..6] |
|
Region A: Residues: [1-389] |
1 11 21 31 41 51
| | | | | |
1 MASTDCYLAL EDGTVLPGYS FGYVPSENES KVGFGGEVVF QTGMVGYTEA LTDRSYSGQI 60
61 LVLTYPLIGN YGVPAPDEDE HGLPLHFEWM KGVVQATALV VGEVAEEAFH WRKWKTLPDW 120
121 LKQHKVPGIQ DIDTRALTKK LREQGSMLGK IVYEKPPVEG LPKSSFVDPN VRNLAKECSV 180
181 KERQVYGNPN GKGPRIAILD CGLKLNQLRC LLQRGASVTL LPWSARLEDE QFDALFLSNG 240
241 PGNPESCDQI VQQVRKVIEE GQKPVFGICL GHQLLAKAIG CSTYKMKYGN RGHNLPCLHR 300
301 ATGRCLMTSQ NHGYAVDLEQ LPDGWSELFV NANDGTNEGI VHASKPYFSV QFHPEHHAGP 360
361 QDTEFLFDVF MESIQQKDLT IPQLIEQRL
|
| Detection Method: |  |
| Confidence: | 125.0 |
| Match: | 1m6vB |
| Description: | Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 11.6556846811261 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase activity | 11.614541080865 | bayes_pls_golite062009 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 8.83104490344765 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 6.7523653122648 | bayes_pls_golite062009 |
| ligase activity | 2.64230127203047 | bayes_pls_golite062009 |
| nucleic acid binding | 1.83357525248647 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.68223120807504 | bayes_pls_golite062009 |
| kinase activity | 1.67508566693087 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.57588199570083 | bayes_pls_golite062009 |
| transferase activity | 1.56222597521764 | bayes_pls_golite062009 |
| phosphoribosylformylglycinamidine synthase activity | 1.51568729563523 | bayes_pls_golite062009 |
| binding | 1.22860407524238 | bayes_pls_golite062009 |
| catalytic activity | 0.902495165806215 | bayes_pls_golite062009 |
| transferase activity, transferring glycosyl groups | 0.774587372455935 | bayes_pls_golite062009 |
| hydrolase activity | 0.488948677783382 | bayes_pls_golite062009 |
| imidazoleglycerol-phosphate synthase activity | 0.270391651600004 | bayes_pls_golite062009 |
| anthranilate synthase activity | 0.243205818526006 | bayes_pls_golite062009 |
| peptidase activity | 0.0466975117232061 | bayes_pls_golite062009 |
| protein binding | 0.0152024556625711 | bayes_pls_golite062009 |
|
Region A: Residues: [390-1459] |
1 11 21 31 41 51
| | | | | |
1 RPTTPAIDSA PVMPRKVLIL GSGGLSIGQA GEFDYSGSQA IKAMRESNIQ TVLINPNIAT 60
61 VQTSKGMADK CYFLPLTPHY VEQVIKSERP NGVLLTFGGQ TALNCGVQLE RAGVFSKYNV 120
121 RILGTPIQSI IETEDRKLFA ERVNEIGEQV APSEAVYSVA QALDAASRLG YPVMARAAFS 180
181 LGGLGSGFAN NEEELQSLAQ QALAHSSQLI VDKSLKGWKE VEYEVVRDAY NNCITVCNME 240
241 NFDPLGIHTG ESIVVAPSQT LSDREYQMLR STALKVIRHF GVVGECNIQY ALCPHSEQYY 300
301 IIEVNARLSR SSALASKATG YPLAYVAAKL ALGLPLPDIK NSVTGNTTAC FEPSLDYCVV 360
361 KIPRWDLAKF VRVSKHIGSS MKSVGEVMAI GRNFEEAFQK ALRMVDSDVL GFDPDVVPLN 420
421 KEQLAEQLSE PTDRRPFVIA AALQLGMSLR ELHQLTNIDY WFLEKLERII LLQSLLTRNG 480
481 SRTDAALLLK AKRFGFSDKQ IAKYIKSTEL AVRHQRQEFG IRPHVKQIDT VAGEWPASTN 540
541 YLYHTYNGSE HDVDFPGGHT IVVGSGVYRI GSSVEFDWCA VGCLRELRKL QRPTIMINYN 600
601 PETVSTDYDM CDRLYFEEIS FEVVMDIYEM ENSEGIILSM GGQLPNNIAM DLHRQQAKVL 660
661 GTSPESIDCA ENRFKFSRML DRKGILQPRW KELTNLQSAI EFCEEVGYPC LVRPSYVLSG 720
721 AAMNVAYSNQ DLETYLNAAS EVSREHPVVI SKFLTEAKEI DVDAVASDGR ILCMAVSEHV 780
781 ENAGVHSGDA TLVTPPQDLN AETLEAIKRI TCDLASVLDV TGPFNMQLIA KNNELKVIEC 840
841 NVRVSRSFPF VSKTLDHDFV ATATRAIVGL DVEPLDVLHG VGKVGVKVPQ FSFSRLAGAD 900
901 VQLGVEMAST GEVACFGDNR YEAYLKAMMS TGFQIPKNAV LLSIGSFKHK MELLPSIRDL 960
961 AKMGYKLYAS MGTGDFYAEH GVNVESVQWT FDKTTPDDIN GELRHLAEFL ANKQFDLVIN1020
1021 LPMSGGGARR VSSFMTHGYR TRRLAVDYSI PLVTDVKCTK LLVESMRMNG
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1bxrA |
| Description: | Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| carbamoyl-phosphate synthase activity | 10.3961907577933 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 10.3817460390594 | bayes_pls_golite062009 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 7.55690629692775 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 7.41655699341139 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase (ammonia) activity | 5.29301695671381 | bayes_pls_golite062009 |
| ligase activity | 4.44283992739984 | bayes_pls_golite062009 |
| aspartate carbamoyltransferase activity | 3.38433995801364 | bayes_pls_golite062009 |
| dihydroorotase activity | 2.87758723400434 | bayes_pls_golite062009 |
| succinate-CoA ligase activity | 2.77725772893528 | bayes_pls_golite062009 |
| CoA carboxylase activity | 2.53820799209252 | bayes_pls_golite062009 |
| catalytic activity | 2.5009559386228 | bayes_pls_golite062009 |
| carboxyl- or carbamoyltransferase activity | 2.46049425383361 | bayes_pls_golite062009 |
| ligase activity, forming carbon-carbon bonds | 2.27702293106204 | bayes_pls_golite062009 |
| acetyl-CoA carboxylase activity | 2.18226575117684 | bayes_pls_golite062009 |
| CoA-ligase activity | 1.95069402824125 | bayes_pls_golite062009 |
| acid-thiol ligase activity | 1.72672517234442 | bayes_pls_golite062009 |
| phosphoribosylaminoimidazole carboxylase activity | 1.57708889650281 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.43253315277789 | bayes_pls_golite062009 |
| binding | 1.21275677338476 | bayes_pls_golite062009 |
| transferase activity | 1.11190599598314 | bayes_pls_golite062009 |
| phosphoribosylamine-glycine ligase activity | 1.04915286326924 | bayes_pls_golite062009 |
| carbon-oxygen lyase activity, acting on phosphates | 0.964679554894316 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 0.96165574211624 | bayes_pls_golite062009 |
| biotin carboxylase activity | 0.925630424589009 | bayes_pls_golite062009 |
| phosphoribosylaminoimidazolecarboxamide formyltransferase activity | 0.898425265043358 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 0.823961741659657 | bayes_pls_golite062009 |
| succinate-CoA ligase (ADP-forming) activity | 0.731047220665703 | bayes_pls_golite062009 |
| carbon-oxygen lyase activity | 0.482425669839603 | bayes_pls_golite062009 |
| propionyl-CoA carboxylase activity | 0.377204236873769 | bayes_pls_golite062009 |
| hydrolase activity | 0.358639651655949 | bayes_pls_golite062009 |
| glutathione binding | 0.20743435331623 | bayes_pls_golite062009 |
| succinate-CoA ligase (GDP-forming) activity | 0.04189990190488 | bayes_pls_golite062009 |
|
Region A: Residues: [1460-1829] |
1 11 21 31 41 51
| | | | | |
1 GKPPMKTHTD CMTSRRIVKL PGFIDVHVHL REPGATHKED FASGTAAALA GGVTLVCAMP 60
61 NTNPSIVDRE TFTQFQELAK AGARCDYALY VGASDDNWAQ VNELASHACG LKMYLNDTFG 120
121 TLKLSDMTSW QRHLSHWPKR SPIVCHAERQ STAAVIMLAH LLDRSVHICH VARKEEIQLI 180
181 RSAKEKGVKV TCEVCPHHLF LSTKDVERLG HGMSEVRPLL CSPEDQEALW ENIDYIDVFA 240
241 TDHAPHTLAE KRSERPPPGF PGVETILPLL LQAVHEGRLT MEDIKRKFHR NPKIIFNLPD 300
301 QAQTYVEVDL DEEWTITGNE MKSKSGWTPF EGTKVKGRVH RVVLRGEVAF VDGQVLVQPG 360
361 FGQNVRPKQS
|
| Detection Method: | |
| Confidence: | 63.69897 |
| Match: | 1xrfA |
| Description: | The Crystal Structure of a Novel, Latent Dihydroorotase from Aquifex aeolicus at 1.7 A resolution |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| dihydroorotase activity | 5.83804402298952 | bayes_pls_golite062009 |
| hydrolase activity | 3.43682651851542 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | 3.03591306120652 | bayes_pls_golite062009 |
| allantoinase activity | 2.45571277189844 | bayes_pls_golite062009 |
| transcription regulator activity | 2.05422491012934 | bayes_pls_golite062009 |
| deaminase activity | 1.79186203771221 | bayes_pls_golite062009 |
| nucleic acid binding | 1.75483241027992 | bayes_pls_golite062009 |
| catalytic activity | 1.70199291046899 | bayes_pls_golite062009 |
| DNA binding | 1.70075498563244 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 1.60895003474033 | bayes_pls_golite062009 |
| binding | 1.20793368650496 | bayes_pls_golite062009 |
| transcription factor activity | 1.01581417842484 | bayes_pls_golite062009 |
| AMP deaminase activity | 0.8498975324894 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | 0.573107361273483 | bayes_pls_golite062009 |
| deacetylase activity | 0.57075565732108 | bayes_pls_golite062009 |
| guanine deaminase activity | 0.134430884998957 | bayes_pls_golite062009 |
| dihydropyrimidinase activity | 0.101722148781441 | bayes_pls_golite062009 |
|
Region A: Residues: [1830-1896] |
1 11 21 31 41 51
| | | | | |
1 PLASEASQDL LPSDNDANDT FTRLLTSEGP GGGVHGISTK VHFVDGANFL RPNSPSPRIR 60
61 LDSASNT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1897-2224] |
1 11 21 31 41 51
| | | | | |
1 TLREYLQRTT NSNPVAHSLM GKHILAVDMF NKDHLNDIFN LAQLLKLRGT KDRPVDELLP 60
61 GKIMASVFYE VSTRTQCSFA AAMLRLGGRV ISMDNITSSV KKGESLEDSI KVVSSYADVV 120
121 VLRHPSPGAV ARAATFSRKP LINAGDGVGE HPTQALLDIF TIREEFGTVN GLTITMVGDL 180
181 KNGRTVHSLA RLLTLYNVNL QYVAPNSLQM PDEVVQFVHQ RGVKQLFARD LKNVLPDTDV 240
241 LYMTRIQRER FDNVEDYEKC CGHLVLTPEH MMRAKKRSIV LHPLPRLNEI SREIDSDPRA 300
301 AYFRQAEYGM YIRMALLAMV VGGRNTAL
|
| Detection Method: | |
| Confidence: | 98.221849 |
| Match: | 1ml4A |
| Description: | Aspartate carbamoyltransferase catalytic subunit |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| carboxyl- or carbamoyltransferase activity | 8.44774290170513 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 8.39877026738977 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase activity | 8.35868658131065 | bayes_pls_golite062009 |
| aspartate carbamoyltransferase activity | 7.47628089321489 | bayes_pls_golite062009 |
| ornithine carbamoyltransferase activity | 6.08861672645671 | bayes_pls_golite062009 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 5.70428077078256 | bayes_pls_golite062009 |
| transferase activity | 4.46011936943199 | bayes_pls_golite062009 |
| dihydroorotase activity | 4.10312514971972 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 4.09429261864362 | bayes_pls_golite062009 |
| aspartate binding | 3.43574933938267 | bayes_pls_golite062009 |
| UTP binding | 3.43574933938267 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 2.1749430001471 | bayes_pls_golite062009 |
| catalytic activity | 2.06069688716378 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.71477949033699 | bayes_pls_golite062009 |
| kinase activity | 1.70283432187593 | bayes_pls_golite062009 |
| binding | 1.63251597999268 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.5976562586299 | bayes_pls_golite062009 |
| protein kinase activity | 1.48895685647086 | bayes_pls_golite062009 |
| hydrolase activity | 0.628276058923848 | bayes_pls_golite062009 |
| ligase activity | 0.345534785035194 | bayes_pls_golite062009 |
| amine binding | 0.33918556173094 | bayes_pls_golite062009 |
| protein binding | 0.271043612914069 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | 0.254873181665999 | bayes_pls_golite062009 |
