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Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the reaction: guanine + H2O = xanthine + NH3. Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: guanine deaminase activity
Acc: GO:0008892
Aspect: Molecular Function
Desc: Catalysis of the reaction: guanine + H2O = xanthine + NH3.
Synonyms:
  • GAH activity
  • guanine aminohydrolase activity
  • guanase activity
  • guanine aminase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008892 - guanine deaminase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle