YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CG31183-PA, FBpp...
Organism: Drosophila melanogaster
Length: 1417 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31183-PA, FBpp....

Description E-value Query
Range		 Subject
Range
gi|54638991, gi|... - gi|54638991|gb|EAL28393.1| GA16072-PA [Drosophila pseudoobscura], gi|125776349|ref|XP_001359248.1| G...
 808.0 [0..23] [1417..17]

Back

Predicted Domain #1
Region A:
Residues: [1-77] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQAGQGLSL LLILCLLQAH LFPSAAWFYD AESVGGVASI GVGSDEHSFK TPETKNSHKS  60
   61 QSTELVQHFP SLPMPDH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [78-537] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRLGARRQLV FVALLPSVES DNKNDCIMPK VLPVLELAIR HVQRMGFVGG SHFDIQLISR  60
   61 DTFCSSKYGP IGFFEIYTQW PEVNAVFGLP CEYVLAPISR YADVWQVPVL TTGGNAKEFN 120
  121 KKSESYSTLT RLKGAQVNNL GNVVRAILNS FNWTRTALIY QNENAKVKGN SVCFLCLAAI 180
  181 HDTIEEHSVY QLGFDTSTWT KADITRMLKN VAMQSRIVIM CADPQSIRQI MLTAEELNMI 240
  241 DSGEYVFINI ELFSRVQYLT SQPWYDKNDT DLNNERAQKA YTAMLTVTPK QPNDNEYTRV 300
  301 SNEIKAIAAE KYNYTFSDNE PISAFVTSFF DGVLLYANAL NESIREDPTM LTRPINGTDM 360
  361 VRRMWNRSFT GITGNVTIDA NGDRLSAYSL LDMNPTTGRF EIVAHFLHNR LEFEANKEIH 420
  421 WAGDREEAPP DRPICGYDGA LCPDNSLPGY AILSIVLGTM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1dp4A
Description: Hormone binding domain of the atrial natriuretic peptide receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
G-protein coupled receptor activity 5.7202621143437 bayes_pls_golite062009
adenylate cyclase inhibiting metabotropic glutamate receptor activity 4.93954353870922 bayes_pls_golite062009
transcription regulator activity 4.34309008728616 bayes_pls_golite062009
receptor activity 4.1442086696021 bayes_pls_golite062009
transmembrane receptor activity 4.0843113712194 bayes_pls_golite062009
glutamate receptor activity 3.96829643900059 bayes_pls_golite062009
group III metabotropic glutamate receptor activity 3.96653802746406 bayes_pls_golite062009
DNA binding 3.61776323775806 bayes_pls_golite062009
transcription factor activity 3.44509182129646 bayes_pls_golite062009
nucleic acid binding 3.36600402123347 bayes_pls_golite062009
molecular transducer activity 3.17421789884883 bayes_pls_golite062009
signal transducer activity 3.17421789884883 bayes_pls_golite062009
binding 2.92042936761166 bayes_pls_golite062009
peptide receptor activity 2.69138343857418 bayes_pls_golite062009
guanylate cyclase activity 2.42987465654642 bayes_pls_golite062009
group II metabotropic glutamate receptor activity 2.02460911416872 bayes_pls_golite062009
cyclase activity 1.95391742402237 bayes_pls_golite062009
transporter activity 1.94865852692163 bayes_pls_golite062009
PLC activating metabotropic glutamate receptor activity 1.93160762343283 bayes_pls_golite062009
transmembrane transporter activity 1.83955873328417 bayes_pls_golite062009
amine binding 1.6373817551539 bayes_pls_golite062009
peptide binding 1.60700803165111 bayes_pls_golite062009
phosphorus-oxygen lyase activity 1.51094915686986 bayes_pls_golite062009
substrate-specific transporter activity 1.45087364463083 bayes_pls_golite062009
natriuretic peptide receptor activity 1.3877109000054 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.34941602745967 bayes_pls_golite062009
active transmembrane transporter activity 1.30369066890706 bayes_pls_golite062009
primary active transmembrane transporter activity 1.29881269915303 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.29466697797865 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1.27441358428626 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 1.27125980233959 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 1.27088454405241 bayes_pls_golite062009
carbohydrate binding 1.24878820273096 bayes_pls_golite062009
protein binding 1.23723635587647 bayes_pls_golite062009
transcription activator activity 1.23600343828473 bayes_pls_golite062009
taste receptor activity 1.21173489127635 bayes_pls_golite062009
sugar binding 0.95501261360996 bayes_pls_golite062009
peptide receptor activity, G-protein coupled 0.830628582065238 bayes_pls_golite062009
peptide hormone binding 0.744531200386629 bayes_pls_golite062009
ATPase activity, coupled 0.688251096406204 bayes_pls_golite062009
amino acid binding 0.64866609432579 bayes_pls_golite062009
transcription repressor activity 0.56157419182036 bayes_pls_golite062009
ATPase activity 0.486508168109568 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.481441942208549 bayes_pls_golite062009
pyrophosphatase activity 0.419287381048087 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.403674689236963 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.400732473817975 bayes_pls_golite062009
glutamate binding 0.345623202096461 bayes_pls_golite062009
ion transmembrane transporter activity 0.265482111518448 bayes_pls_golite062009
gated channel activity 0.197987086788784 bayes_pls_golite062009
cation transmembrane transporter activity 0.0604479939440918 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [538-867] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVVMAVCFFF GYRHYIAEAE INSMSWKVSL EDVMFRDAAE RGLRGSFHSL VKQSSQLTLM  60
   61 SEDMVSINGD RQIFIPVGMF RKSKVAIKPV EVDNVQGLLT RSLMLELKRM KDLQHDHLVK 120
  121 FYGACLDQRR SFLLTEYCPK GSLQDILENE QFQLDWMFRL SLMHDIVRGM QFLHSSDIRS 180
  181 HGNLKSSNCV VDSRFVLKIT DFGLHTLRRT RFDLESDGGN CNSHAYWSKL LWTAPELLRV 240
  241 EHNRPPEGTQ KGDVYAFGII VHEITTRQGP FYLGRCAYEK SPQEIIELVK GYNPHRMQKP 300
  301 FRPELEPNGD TKADINGIIR RCWAEDPAER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.30103
Match: 2helA
Description: No description for 2helA was found.

Predicted Domain #4
Region A:
Residues: [868-992] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDFNTLKSMI RRFNKDNETG NIVDNLLKRM ELYANNLEEL VEERTQDYHE EKKKCEKLLY  60
   61 QLLPQSVAAQ LISGQPVVAE TFDQVTIYFS DIVGFTAISA ESTPMQVVQF LNDLYTCFDS 120
  121 IVENF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.74
Match: 1wc1A
Description: Soluble adenylyl cyclase CyaC from S. platensis in complex with Rp- ATPalphaS
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [993-1148] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVYKVETIGD AYMVVSGLPI RNGNQHAREI ARLALALLEA VHNFRIHHRP EDRLKLRIGL  60
   61 HTGACVAGVV GLKMPRYCLF GDTVNTASRM ESNGEALKIH ISETTKEALD EFGTFVTTRR 120
  121 GFVPMKGKGE MLTYWLEGEV PRPNSLISPS KLMLTR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.045757
Match: 1yk9A
Description: Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1149-1282] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSSLKQPQRS QSHNLHKQYS ELVVASPPPQ LPPPAIALPP PPSPSKDSPN LRVKRKISSS  60
   61 SPKLNGGGFD YHKTENHYLD TAAAAQRNCD IYSSRSLRDM EETSDSWELA HFRLPLSGAL 120
  121 KSHHHLNNNS HGYV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1283-1417] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSNSSSNLSG ILQPPPLGVQ RTRLKPSPTI STLLTSARSE ANASPGPETG SMGSGQLRIK  60
   61 FAEGDETPLL PTPPPLAAPP PIPQMVAASP QRSGSGQNIP ADSSHYGFLV KSYKQQCPPV 120
  121 AGSAVTQPLL AKINS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle