| Protein: | spn-E-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1434 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spn-E-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1129.0 | [0..1] | [1434..1] |
|
Region A: Residues: [1-524] |
1 11 21 31 41 51
| | | | | |
1 MDQEVMDFFD FSKELKRVAA APQGYISSDP RLMATKFKSS EVPNRELIGT DYVSKIVAKE 60
61 KCLLNGTLLN EQPQGKRIRT LDDLDTDDEG EETEIRRDDE YYKKFRFNLN RDKNLSIYAK 120
121 REEILAAINA HPVVIIKGET GCGKTTQVPQ YILDEAYKSG KYCNIVVTQP RRIAAISIAN 180
181 RVCQEREWQQ NTVCSFQVGL HRPNSLEDTR LLYCTTGVLL NNLINNKTLT HYTHIVLDEV 240
241 HERDQNMDFL LIVVRRLLAT NSRHVKIILM SATIDAKELS DYFTTTNSIP PVITTNHRRK 300
301 HSIEKFYRDQ LGSIIWNEED VGHQQVPEIN KHGYRAAVKI IVIIDNMERK AAIQSRQSYD 360
361 EALRYGAVLI FLPGIYEIDT MAENLTCMLE NDPNIKVSIV RCFSLMTPEN QRDVFNPPPP 420
421 GFRKIILTTN IAESSITVPD VSYVIDFCLA KVKVTDTASS FSSLRLTWAS KANCRQRAGR 480
481 VGRLRSGRVY RMVNKHFYQR EMPEFGIPEM LRLPLQNSVL KAKV
|
| Detection Method: |  |
| Confidence: | 62.39794 |
| Match: | 2hyiC |
| Description: | No description for 2hyiC was found. |
| Term | Confidence | Notes |
| 4.704140727858 | bayes_pls_golite062009 | |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.59795224939987 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.53105050016344 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.51138588650702 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.50855799768914 | bayes_pls_golite062009 |
| RNA binding | 2.29590582680214 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| ATPase activity | 1.98450701262305 | bayes_pls_golite062009 |
| transporter activity | 1.96221407589423 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.80814406142572 | bayes_pls_golite062009 |
| ATPase activity, coupled | 1.77868357168224 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.68112322593144 | bayes_pls_golite062009 |
| RNA helicase activity | 1.42791449104435 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.39335733374328 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.36724390116598 | bayes_pls_golite062009 |
| hydrolase activity | 1.22195710211319 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.77342981918307 | bayes_pls_golite062009 |
| mRNA binding | 0.76699944561918 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.725611289205392 | bayes_pls_golite062009 |
| nucleotide binding | 0.717697610309727 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.713814218071151 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.713752628021599 | bayes_pls_golite062009 |
| motor activity | 0.70874549510465 | bayes_pls_golite062009 |
| structural molecule activity | 0.70126232242991 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| GTPase activity | 0.437665353870877 | bayes_pls_golite062009 |
| snRNA binding | 0.418985924846052 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.397504938442906 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.312659433116074 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.296406132096546 | bayes_pls_golite062009 |
| GTP binding | 0.295705904888768 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.29028316917561 | bayes_pls_golite062009 |
| ATP binding | 0.19169045543599 | bayes_pls_golite062009 |
| translation release factor activity | 0.178286731022211 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.165732470448462 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.162060759063149 | bayes_pls_golite062009 |
| translation termination factor activity | 0.151456842619444 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.114463153989353 | bayes_pls_golite062009 |
| signal sequence binding | 6.53725193420218E-4 | bayes_pls_golite062009 |
|
Region A: Residues: [525-568] |
1 11 21 31 41 51
| | | | | |
1 LNMGSPVEIL ALALSPPNLS DIHNTILLLK EVGALYLTVD GIYD
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 1c4oA |
| Description: | Nucleotide excision repair enzyme UvrB |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [569-699] |
1 11 21 31 41 51
| | | | | |
1 PLDGDLTYWG TIMSRLPLDT RQSRLIILGY IFNMLEEAII IAAGLSTPGL FAHEGGRSQL 60
61 GDSFWMHYIF SDGSGSDLVA IWRVYLTYLN IVENGHDQES AIRWAKRFHV SLRSLKEIHL 120
121 LVQELRVRCT H
|
| Detection Method: | |
| Confidence: | 1.13 |
| Match: | 2v8oA |
| Description: | No description for 2v8oA was found. |
|
Region A: Residues: [700-881] |
1 11 21 31 41 51
| | | | | |
1 LGLIPFPVNP NQMMDDREKA IMLKVIIAGA FYPNYFTRSK ESCADTDRNI YQTISGHDPC 60
61 RTVYFTNFKP AYMGELYTRR IKELFQEVRI PPENMDVTFQ EGSQKVFVTF KQDDWIEGSS 120
121 KYVPVSGRVQ SEVYKAVMMR QNRVERPIHI MNPSAFMSYV QQRGIGDVIE GRWIPPTKPL 180
181 NV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [882-1146] |
1 11 21 31 41 51
| | | | | |
1 ELLALPSVFD KTISGSITCI VNCGKFFFQP QSFEECIRNM SEIFNAPQQL RNYVTNASAI 60
61 AKGMMVLAKR DSYFQRATVI RPENQSNRQP MFYVRFIDYG NCTLLPMQLM RLMPRELTEQ 120
121 YGDLPPRVFE CRLAMVQPSS VVSGNNRWST AANDMLKTVA QCGLIDIEVY SLFNNVAAVL 180
181 IHMRDGIIND KLVELMLCRR SDEDYMSRKD HDFRLRRQES ARNLSTAQRQ QINEEYLRSC 240
241 QLPQDHDLPP PPLEKCKTVV MLKGP
|
| Detection Method: | |
| Confidence: | 28.39794 |
| Match: | 2hqeA |
| Description: | No description for 2hqeA was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 3.34067645460735 | bayes_pls_golite062009 |
| transcription repressor activity | 3.21000367413295 | bayes_pls_golite062009 |
| binding | 3.03932294945523 | bayes_pls_golite062009 |
| nucleic acid binding | 2.39870293911569 | bayes_pls_golite062009 |
| DNA binding | 2.38812251097879 | bayes_pls_golite062009 |
| histone methyltransferase activity | 2.18526516649831 | bayes_pls_golite062009 |
| histone binding | 2.01213085278409 | bayes_pls_golite062009 |
| protein binding | 1.76914488602752 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 1.69262589010127 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 1.69262589010127 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 1.69262589010127 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.65392797012899 | bayes_pls_golite062009 |
| DNA-methyltransferase activity | 1.61102752615076 | bayes_pls_golite062009 |
| transcription factor binding | 1.49481919243505 | bayes_pls_golite062009 |
| transcription factor activity | 1.41108699101741 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.36802409360413 | bayes_pls_golite062009 |
| DNA (cytosine-5-)-methyltransferase activity | 1.34644198396495 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.3138976673316 | bayes_pls_golite062009 |
| methylated histone residue binding | 0.89251037476759 | bayes_pls_golite062009 |
| chromatin binding | 0.8915883636553 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.56323697625529 | bayes_pls_golite062009 |
| N-methyltransferase activity | 0.53946303154276 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 0.52209845652926 | bayes_pls_golite062009 |
| transcription activator activity | 0.262486595331603 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 0.223495463070134 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.141502107934206 | bayes_pls_golite062009 |
|
Region A: Residues: [1147-1353] |
1 11 21 31 41 51
| | | | | |
1 NSPLECTMRS ITRVGLSKRV NIDHLSVNAL LLDADPQDHH DHLIVAHEIA ESRNGQTLTA 60
61 RGTTLMPNVQ GFGALMVMLF SPTMQLKCNK EGTSYVSVLG GLGCDPDTNE PYFAEHDVLI 120
121 NLDVNILEDD VILINQIRYY IDSVFFNFKE ENNPAVSVNE RVSIYTQLRS LINRLLCKDR 180
181 RYIERNMSNA DFEWETNPEL PLPNEPF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1354-1434] |
1 11 21 31 41 51
| | | | | |
1 GKRAIFPMHS LTELQEEDTG RLVQLRENCS MLHKWRNFEG TLPHMTCKLC NQLLESVPQL 60
61 RLHLLTILHR DREKQIDYCN Q
|
| Detection Method: | |
| Confidence: | 1.29 |
| Match: | 1zu1A |
| Description: | Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.47951889934838 | bayes_pls_golite062009 |
| nucleic acid binding | 4.35187767955595 | bayes_pls_golite062009 |
| DNA binding | 4.31051339571017 | bayes_pls_golite062009 |
| transcription factor activity | 3.28758716579796 | bayes_pls_golite062009 |
| RNA binding | 3.11293528368816 | bayes_pls_golite062009 |
| transcription repressor activity | 3.07956158665183 | bayes_pls_golite062009 |
| binding | 2.99742524370422 | bayes_pls_golite062009 |
| snRNA binding | 2.38635340504238 | bayes_pls_golite062009 |
| U1 snRNA binding | 2.10135521534215 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.05542379535543 | bayes_pls_golite062009 |
| transcription activator activity | 1.97757778483124 | bayes_pls_golite062009 |
| mRNA binding | 1.28525296322454 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.26862497534835 | bayes_pls_golite062009 |
| chromatin binding | 1.26688155139311 | bayes_pls_golite062009 |
| transcription factor binding | 1.23738346570539 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.16887811832337 | bayes_pls_golite062009 |
| protein binding | 0.952480850696098 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.776754909146767 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.627794176881836 | bayes_pls_golite062009 |
| catalytic activity | 0.263007611601737 | bayes_pls_golite062009 |
| histone binding | 0.088089875173164 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.0855506955761403 | bayes_pls_golite062009 |
