| Protein: | FBpp0304259, Alk-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1701 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304259, Alk-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1320.0 | [0..20] | [1701..1] |
|
Region A: Residues: [1-231] |
1 11 21 31 41 51
| | | | | |
1 MPQLRQLVVV LAILSLLVDP SFAQRPLIMN HTFSSLPMSQ HPSFNSWPSA SGGKQLRNGR 60
61 LHEQPLPLPQ PTLPVATQYE DYEAAPPGSR RDNKRRLAQM AQRPGSGNGG RRGMESLRKE 120
121 LMNPSVGGPG GGISGGGSGY PSYSATSSIG RIDGLGQGLG SADRYGALYD QLRQPSGMAA 180
181 MTAGPLGGPY STRFPPLYAG VDDQPKRSNR KNSISELYKL KKALNQADEP A
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [232-538] |
1 11 21 31 41 51
| | | | | |
1 GGVTHGNFEG DPQPSSADPL QEIKDRIRDT SPNANTYAPH TDATPSSEYE YELGVKCNFE 60
61 TPCSWTWGNY SDGFQVITGT ELSKRNLTGL LPGPAADSID DANGHFLYAR VNPSSRPLNL 120
121 TSPEFSTTME KCFLEVYMHQ SDMSHGLSRV VVELLHTAES SWVPAEILGD NVRQWTRKVY 180
181 RLGRVSRDFR IVFEVVPDLR VGQKGHVALD NLRMVNCFPE GTKSEKCSTS QVKCTSSKVP 240
241 VCIHLPRICD ITRDCDEAED EQQSCDKIPY GGRCDFEEDW CGWRDSGKTT LTWSRHTGSS 300
301 PTHDTGP
|
| Detection Method: | |
| Confidence: | 28.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [539-700] |
1 11 21 31 41 51
| | | | | |
1 DGDHTMQHLQ NNTSGYYMLV NMNQHMNNSE KNSIIGFASN AIMVSKTFNP PPSVHGNPDS 60
61 PYRNSCVVRF FIHQFGKNPG SINLSVVEMK EKENITTTLW WSTKNQGSDW MRAEYVLPNI 120
121 TSKYYLQFEA RMGMRIYSDV AVDDFSLSPE CFGLNIPEDH LG
|
| Detection Method: | |
| Confidence: | 19.69897 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [701-795] |
1 11 21 31 41 51
| | | | | |
1 GYNYWDVRQN LKSPTYKDFE YTNYLELTTC DTRGMIGPSQ AQCEAAYREQ NKTHVLREVH 60
61 VVEDQSSYKG MQKWKVPHEG HYTIIAKGAS GGLGS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [796-935] |
1 11 21 31 41 51
| | | | | |
1 GGVGSSRGSV AVAILELHKN EELYFLVGQQ GENACIKSMG VLKEAGCGTD HDLDLAQYSF 60
61 RSKQDMVKNI YIENGAGGGG GGSYVFLLNQ AKNEAVPLLV AGGGGGLGIG QYIDEDFQHG 120
121 QKAKPLQAPE SGQINGEPLN
|
| Detection Method: | |
| Confidence: | 17.30103 |
| Match: | 1ry7B |
| Description: | Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [936-1477] |
1 11 21 31 41 51
| | | | | |
1 KKTAGPGGGW RAKEDQALSP TYGAALLQGG RGGHSCYVEL ADNGTSVHRH GQGGFGGGGG 60
61 GCNTGGGGGG YAGGDVYLTE SNGEGGSSYI SPSRSLREIS EIHAGASSGP GAIIIIPAIE 120
121 GCGCDYRCVA LDEFRSKVRC ICPDGWSLKR DNHTACEIRE EAGKSSFQYL VSILMISLAV 180
181 LFICIAALIF MLYNRYQRKK QSKKRHKMLV EQDLQLTRLR NNIDDSNLNN FNPNYGCDGI 240
241 LNGHIDVNSL PQVARDSLQL VNALGKGAFG EVYMALYRHR DGDAVEMGVA VKTLREDPKR 300
301 EKEEDFLKEA AIMAKFNHPN MVHLIGVCFD RQPYYIVLEL LAGGDLQKFL RENRNTPERP 360
361 SLLTMKDLLF CALDVAKGCR YMESKRFIHR DIAARNCLLS SKGPGRVVKI ADFGMSRDIY 420
421 RSDYYRKGGK AMLPIKWMPP EAFLDGIFTS KTDVWSFGIL LWEVFSLGRS PYPGQHNTQV 480
481 MELVVRGGRL GSPTECPVSI YKVMADCWNP TPEDRPTFIT LLEHLTACTQ DASIMNAPLP 540
541 NI
|
| Detection Method: | |
| Confidence: | 72.522879 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 4.09909681656699 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.1965684217331 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| receptor activity | 2.96273889901429 | bayes_pls_golite062009 |
| signal transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| molecular transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 2.70917101514973 | bayes_pls_golite062009 |
| growth factor binding | 2.61235080252818 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.9011085456623 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.51779793980227 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.51779793980227 | bayes_pls_golite062009 |
| integrin binding | 1.44154155381408 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.95914323793919 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| transporter activity | 0.710766490066447 | bayes_pls_golite062009 |
| actin filament binding | 0.66248865719696 | bayes_pls_golite062009 |
| nucleic acid binding | 0.655396214040669 | bayes_pls_golite062009 |
| transcription regulator activity | 0.631882811427766 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.610230065465794 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.60324822483033 | bayes_pls_golite062009 |
| DNA binding | 0.599969415455862 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| transcription factor activity | 0.457173041568166 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385603245903806 | bayes_pls_golite062009 |
| insulin receptor activity | 0.359260732334699 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.349343975617553 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.294256794094724 | bayes_pls_golite062009 |
| transforming growth factor beta binding | 0.287757704969289 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.233896787419349 | bayes_pls_golite062009 |
| polysaccharide binding | 0.229808864843639 | bayes_pls_golite062009 |
| cytokine binding | 0.17817111033393 | bayes_pls_golite062009 |
| activin receptor activity | 0.163693280420599 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.152203945257581 | bayes_pls_golite062009 |
|
Region A: Residues: [1478-1559] |
1 11 21 31 41 51
| | | | | |
1 LGPTASERDD TVIRPPNGEE FCLAVPDYLV PLPPGGSNNP SMASGSGYVP ELQRQQMSSC 60
61 TPPAVTSPAA PHPRPVENIA PT
|
| Detection Method: | |
| Confidence: | 77.221849 |
| Match: | 2qoqA |
| Description: | No description for 2qoqA was found. |
|
Region A: Residues: [1560-1701] |
1 11 21 31 41 51
| | | | | |
1 SGDCWETSFI LPNSKVEPPV VGSGHDVPLA GGEEAKLISL DTPQPTPTTI QPPLSFASQL 60
61 DGITLDPSAL TKSLPNGNAK QSYANVQVKN EAEAKVINGV VGNGTVMNGD VSTGSGGADS 120
121 PFTIQGYAER YKDNNNHSEI SC
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
