| Protein: | Nrk-PA |
| Organism: | Drosophila melanogaster |
| Length: | 724 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Nrk-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
686.0 | [0..1] | [724..1] |
|
Region A: Residues: [1-139] |
1 11 21 31 41 51
| | | | | |
1 MAAGQWVGVV ERVLRGMVLK WGANLAVLGL CVFLFASATH ANSLNAIEEP VTRRHHQRHH 60
61 EREREENGYC APYSGKVCKE YLTGQVWYSL EDPTGGWKNE QVTTALWDEL ISDLTGLCRE 120
121 AAEKMLCAYA FPNCHMEGG
|
| Detection Method: |  |
| Confidence: | 1.95 |
| Match: | 1ijyA |
| Description: | Frizzled 8 (FZ8) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transmembrane receptor activity | 4.12744895314187 | bayes_pls_golite062009 |
| receptor activity | 3.87682364042772 | bayes_pls_golite062009 |
| signal transducer activity | 3.01939524477326 | bayes_pls_golite062009 |
| molecular transducer activity | 3.01939524477326 | bayes_pls_golite062009 |
| Wnt receptor activity | 2.31013454239678 | bayes_pls_golite062009 |
| binding | 2.1646903962543 | bayes_pls_golite062009 |
| protein binding | 2.08965369645498 | bayes_pls_golite062009 |
| Wnt-protein binding | 1.42144939971845 | bayes_pls_golite062009 |
|
Region A: Residues: [140-285] |
1 11 21 31 41 51
| | | | | |
1 RAVKAPLCFE DCQATHLQFC YNDWVLIEEK KERNMFIKSR GHFRLPNCSS LPHYNASMRR 60
61 PNCSYIGLTE LKESEVSYDC RNGNGRFYMG TMNVSKSGIP CQRWDTQYPH KHFQPPLVFH 120
121 QLLEGENYCR NAGGEEPHPW CYTVDE
|
| Detection Method: | |
| Confidence: | 25.39794 |
| Match: | 1ki0A |
| Description: | Plasminogen |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 2.74055213309696 | bayes_pls_golite062009 |
| signal transducer activity | 2.11223109564776 | bayes_pls_golite062009 |
| molecular transducer activity | 2.11223109564776 | bayes_pls_golite062009 |
| binding | 1.90408871052739 | bayes_pls_golite062009 |
| protein binding | 1.52504676895038 | bayes_pls_golite062009 |
| hydrolase activity | 0.946525235212821 | bayes_pls_golite062009 |
| catalytic activity | 0.280235123429996 | bayes_pls_golite062009 |
|
Region A: Residues: [286-386] |
1 11 21 31 41 51
| | | | | |
1 SVRWQHCDIP MCPDYVDPNA VDLNTPIKME KFFTPSMIFL LAGIGFVAIV TLHLMILLVY 60
61 KLSKHKDYSQ PAGAATAECS VSMRGGGDCG GNLNTSRETL G
|
| Detection Method: | |
| Confidence: | 4.154902 |
| Match: | 2ablA |
| Description: | SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 3.13677730481089 | bayes_pls_golite062009 |
| binding | 3.06905798270146 | bayes_pls_golite062009 |
| actin filament binding | 2.59742039155224 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.21254869336424 | bayes_pls_golite062009 |
| signal transducer activity | 1.80011194349017 | bayes_pls_golite062009 |
| molecular transducer activity | 1.80011194349017 | bayes_pls_golite062009 |
| actin binding | 1.79651396322487 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| receptor binding | 1.14419687627233 | bayes_pls_golite062009 |
| transporter activity | 0.896907103596953 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.80673395326897 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.713068405985864 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.500685400112742 | bayes_pls_golite062009 |
| insulin receptor binding | 0.275913005279959 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.272368655500689 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.00318812576030902 | bayes_pls_golite062009 |
|
Region A: Residues: [387-724] |
1 11 21 31 41 51
| | | | | |
1 GNGNTNTLAK WGTIRSTATI HSNCVALTTV TNVSDAKGTK PNARLEKLEY PRGDIVYVRS 60
61 LGQGAFGRVF QARAPGLVPD QEDLLVAVKM LKDDASDQMQ MDFEREACLL AEFDHPNIVR 120
121 LLGVCALGRP MCLLFEYMAP GDLSEFLRAC SPYATHQAPT QDRLQLNELH LLQMAANIAA 180
181 GMLYLSERKF VHRDLATRNC LINEHMAVKI ADFGLSHKIY LQDYYKGDEN DFIPIRWMPL 240
241 ESILYNKFSL ESDVWAYGIC LWEVFSFALQ PYFGLTHEEV IKYIKEGNVL GCPDNTPLSV 300
301 YALMRRCWNR KPSERPGFAE INHCIQHSIA ESECKAML
|
| Detection Method: | |
| Confidence: | 72.39794 |
| Match: | 1lufA |
| Description: | Musk tyrosine kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 4.09909681656699 | bayes_pls_golite062009 |
| stem cell factor receptor activity | 3.82614202737632 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.1965684217331 | bayes_pls_golite062009 |
| receptor activity | 2.96273889901429 | bayes_pls_golite062009 |
| molecular transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| signal transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 2.70917101514973 | bayes_pls_golite062009 |
| growth factor binding | 2.61235080252818 | bayes_pls_golite062009 |
| transferase activity | 2.34875558765742 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.9011085456623 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.51779793980227 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.51779793980227 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transcription regulator activity | 1.10597058961079 | bayes_pls_golite062009 |
| nucleic acid binding | 1.06086848160606 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| receptor binding | 0.990272341309676 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.95914323793919 | bayes_pls_golite062009 |
| DNA binding | 0.956433441855102 | bayes_pls_golite062009 |
| transcription activator activity | 0.955593006663586 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.867779574651545 | bayes_pls_golite062009 |
| insulin-like growth factor binding | 0.82854091092242 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| transcription factor activity | 0.790106588313006 | bayes_pls_golite062009 |
| platelet-derived growth factor receptor binding | 0.770658204347392 | bayes_pls_golite062009 |
| transporter activity | 0.710766490066447 | bayes_pls_golite062009 |
| growth factor activity | 0.707777793848936 | bayes_pls_golite062009 |
| actin filament binding | 0.66248865719696 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.610230065465794 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.60324822483033 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.516151105278102 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385603245903806 | bayes_pls_golite062009 |
| insulin receptor activity | 0.359260732334699 | bayes_pls_golite062009 |
| polysaccharide binding | 0.344522125452779 | bayes_pls_golite062009 |
| heparin binding | 0.334438853447262 | bayes_pls_golite062009 |
| transforming growth factor beta binding | 0.287757704969289 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.233896787419349 | bayes_pls_golite062009 |
| cytokine binding | 0.17817111033393 | bayes_pls_golite062009 |
| activin receptor activity | 0.163693280420599 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.152203945257581 | bayes_pls_golite062009 |
| hydrolase activity | 0.0498504410225162 | bayes_pls_golite062009 |
