| Protein: | Dscam-PAO |
| Organism: | Drosophila melanogaster |
| Length: | 2032 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAO.
| Description | E-value | Query Range |
Subject Range |
|
|
1526.0 | [0..3] | [2032..3] |
|
Region A: Residues: [1-138] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVN
|
| Detection Method: |  |
| Confidence: | 79.69897 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [139-540] |
1 11 21 31 41 51
| | | | | |
1 QFYEAEIMTE YVIRGNAAVL KCSIPSFVAD FVRVESWIDD EGNVLSFSDN YDGKYLVLPS 60
61 GELHIREVGP EDGYKSYQCR TKHRLTGETR LSATKGRLVI TEPIGARAPT FSTDSNSFSY 120
121 TRSVGQSFAL LCQAQAYPVP IMRWYKFIEG TTRKQAVVLN DRVKQVSGTL IIKDAVVEDS 180
181 GKYLCVVNNS VGGESVETVL TVTAPLSAKI DPPTQTVDFG RPAVFTCQYT GNPIKTVSWM 240
241 KDGKAIGHSE PVLRIESVKK EDKGMYQCFV RNDQESAEAS AELKLGGRFD PPVIRQAFQE 300
301 ETMEPGPSVF LKCVAGGNPT PEISWELDGK KIANNDRYQV GQYVTVNGDV VSYLNITSVH 360
361 ANDGGLYKCI AKSKVGVAEH SAKLNVYGLP YIRQMEKKAI VA
|
| Detection Method: | |
| Confidence: | 55.69897 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [541-624] |
1 11 21 31 41 51
| | | | | |
1 GETLIVTCPV AGYPIDSIVW ERDNRALPIN RKQKVFPNGT LIIENVERNS DQATYTCVAK 60
61 NQEGYSARGS LEVQVMVPPQ IQAF
|
| Detection Method: | |
| Confidence: | 11.39794 |
| Match: | 1mcoH |
| Description: | Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma; Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma; Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| receptor activity | 4.00123250685257 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.81769911097805 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| molecular transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| signal transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| growth factor binding | 2.28613301180608 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
| antigen binding | 1.63189745559168 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.52958974617075 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.30657787244536 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 1.24730237107473 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.02428106476324 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| protein complex binding | 0.83543827718565 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| collagen binding | 0.729893120256353 | bayes_pls_golite062009 |
| peptide binding | 0.729048089532569 | bayes_pls_golite062009 |
| immunoglobulin binding | 0.64138121404685 | bayes_pls_golite062009 |
| receptor binding | 0.632627479346393 | bayes_pls_golite062009 |
| cytokine binding | 0.631436442105379 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| cell surface binding | 0.477483205369537 | bayes_pls_golite062009 |
| cytokine receptor activity | 0.34165331857492 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| immunoglobulin receptor activity | 0.117547357032989 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
| transferase activity | 0.053007146193305 | bayes_pls_golite062009 |
|
Region A: Residues: [625-811] |
1 11 21 31 41 51
| | | | | |
1 DFGSEAANTG EMAGGFCMVP KGDLPMEIRW TLNSAPIITG EHGFSLSRLN PRTSSLSIDS 60
61 LEARHRGLYR CIASNKAGSA EYSAELHVNV PPRWILEPTD KAFAQGSDAK VECKADGFPK 120
121 PQVTWKKAVG DTPGEYKDLK KSDNIRVEEG TLHVDNIQKT NEGYYLCEAI NGIGSGLSAV 180
181 IMISVQA
|
| Detection Method: | |
| Confidence: | 13.39794 |
| Match: | 2c5dC |
| Description: | Structure of a minimal Gas6-Axl complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [812-916] |
1 11 21 31 41 51
| | | | | |
1 PPEFTEKLRN QTARRGEPAV LQCEAKGEKP IGILWNMNNM RLDPKNDNRY TIREEILSTG 60
61 VMSSLSIKRT ERSDSALFTC VATNAFGSDD ASINMIVQEV PEMPY
|
| Detection Method: | |
| Confidence: | 35.522879 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [917-1103] |
1 11 21 31 41 51
| | | | | |
1 ALKVLDKSGR SVQLSWAQPY DGNSPLDRYI IEFKRSRASW SEIDRVIVPG HTTEAQVQKL 60
61 SPATTYNIRI VAENAIGTSQ SSEAVTIITA EEAPSGKPQN IKVEPVNQTT MRVTWKPPPR 120
121 TEWNGEILGY YVGYKLSNTN SSYVFETINF ITEEGKEHNL ELQNLRVYTQ YSVVIQAFNK 180
181 IGAGPLS
|
| Detection Method: | |
| Confidence: | 35.09691 |
| Match: | 1fnfA |
| Description: | FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1104-1500] |
1 11 21 31 41 51
| | | | | |
1 EEEKQFTAEG TPSQPPSDTA CTTLTSQTIR VGWVSPPLES ANGVIKTYKV VYAPSDEWYD 60
61 ETKRHYKKTA SSDTVLHGLK KYTNYTMQVL ATTAGGDGVR SVPIHCQTEP DVPEAPTDVK 120
121 ALVMGNAAIL VSWRPPAQPN GIITQYTVYS KAEGAETETK TQKVPHYQMS FEATELEKNK 180
181 PYEFWVTAST TIGEGQQSKS IVAMPSDQVP AKIASFDDTF TATFKEDAKM PCLAVGAPQP 240
241 EITWKIKGVE FSANDRMRVL PDGSLLIKSV NRQDAGDYSC HAENSIAKDS ITHKLIVLAP 300
301 PQSPHVTLSA TTTDALTVKL KPHEGDTAPL HGYTLHYKPE FGEWETSEVS VDSQKHNIEG 360
361 LLCGSRYQVY ATGFNNIGAG EASDILNTRT KGQKPKL
|
| Detection Method: | |
| Confidence: | 14.522879 |
| Match: | 1zlgA |
| Description: | No description for 1zlgA was found. |
|
Region A: Residues: [1501-1603] |
1 11 21 31 41 51
| | | | | |
1 PEKPRFIEVS SNSVSLHFKA WKDGGCPMSH FVVESKKRDQ IEWNQISNNV KPDNNYVVLD 60
61 LEPATWYNLR ITAHNSAGFT VAEYDFATLT VTGGTIAPLD DGS
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 1bquA |
| Description: | Cytokine receptor gp130 cytokine-binding domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| cell surface binding | 1.05599555585797 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| pattern binding | 0.16768253393396 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1604-1675] |
1 11 21 31 41 51
| | | | | |
1 GHGNVHTRIR LPAWMPEWLD LNFMVPLIAT VVVVAVGICV VCVALSRRRA DDMRGGQKDV 60
61 YYDVVYNQTM GP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1676-1938] |
1 11 21 31 41 51
| | | | | |
1 GATLDKRRPD LRDELGYIAP PNRKLPPVPG SNYNTCDRIK RGRGGLRSNH STWDPRRNPN 60
61 LYEELKAPPV PMHGNHYGHA HGNAECHYRH PGMEDEICPY ATFHLLGFRE EMDPTKAMNF 120
121 QTFPHQNGHA GPVPGHAGTM LPPGHPGHVH SRSGSQSMPR ANRYQRKNSQ GGQSSIYTPA 180
181 PEYDDPANCA EEDQYRRYTR VNSQGGSLYS GPGPEYDDPA NCAPEEDQYG SQYGGPYGQP 240
241 YDHYGSRGSM GRRSIGSARN PGN
|
| Detection Method: | |
| Confidence: | 8.522879 |
| Match: | 2fh7A |
| Description: | Crystal structure of the phosphatase domains of human PTP SIGMA |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1939-2032] |
1 11 21 31 41 51
| | | | | |
1 GSPEPPPPPP RNHDMSNSSF NDSKESNEIS EAECDRDHGP RGNYGAVKRS PQPKDQRTTE 60
61 EMRKLIERNE TGPKQLQLQQ ANGAGFTAYD TMAV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
