| Protein: | Dscam-PAX |
| Organism: | Drosophila melanogaster |
| Length: | 2019 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAX.
| Description | E-value | Query Range |
Subject Range |
|
|
1533.0 | [0..3] | [2019..3] |
|
Region A: Residues: [1-143] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVHQF YQT
|
| Detection Method: |  |
| Confidence: | 79.69897 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [144-242] |
1 11 21 31 41 51
| | | | | |
1 RVIDEFVLRG NSATLKCLVP SFVADFIDVE GWIDEEGVEI LRPLPDDSVD GKYLVLPSGE 60
61 LHIREVGPED GYKSYQCRTK HRLTGETRLS ATKGRLVIT
|
| Detection Method: | |
| Confidence: | 13.09691 |
| Match: | 1f3rB |
| Description: | Immunoglobulin light chain kappa variable domain, VL-kappa; Immunoglobulin heavy chain variable domain, VH |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| receptor activity | 4.00123250685257 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.81769911097805 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| molecular transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| signal transducer activity | 3.10913345555941 | bayes_pls_golite062009 |
| peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| growth factor binding | 2.28613301180608 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
| antigen binding | 1.63189745559168 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.52958974617075 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.30657787244536 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 1.24730237107473 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.02428106476324 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| protein complex binding | 0.83543827718565 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| collagen binding | 0.729893120256353 | bayes_pls_golite062009 |
| peptide binding | 0.729048089532569 | bayes_pls_golite062009 |
| receptor binding | 0.632627479346393 | bayes_pls_golite062009 |
| cytokine binding | 0.631436442105379 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| cytokine receptor activity | 0.34165331857492 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| cell surface binding | 0.213817211551667 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
| transferase activity | 0.053007146193305 | bayes_pls_golite062009 |
|
Region A: Residues: [243-898] |
1 11 21 31 41 51
| | | | | |
1 EPIGARAPTF STDSNSFSYT RSVGQSFALL CQAQAYPVPI MRWYKFIEGT TRKQAVVLND 60
61 RVKQVSGTLI IKDAVVEDSG KYLCVVNNSV GGESVETVLT VTAPLSAKID PPTQTVDFGR 120
121 PAVFTCQYTG NPIKTVSWMK DGKAIGHSEP VLRIESVKKE DKGMYQCFVR NDQESAEASA 180
181 ELKLGGRFDP PVIRQAFQEE TMEPGPSVFL KCVAGGNPTP EISWELDGKK IANNDRYQVG 240
241 QYVTVNGDVV SYLNITSVHA NDGGLYKCIA KSKVGVAEHS AKLNVYGLPY IRQMEKKAIV 300
301 AGETLIVTCP VAGYPIDSIV WERDNRALPI NRKQKVFPNG TLIIENVERN SDQATYTCVA 360
361 KNQEGYSARG SLEVQVMVPP KITPFDFGDA PTNVEDSVSV MCLISNGDLP IDIEWFFNDY 420
421 GISSYSGINV VKGGKRNSML SIDSVQARHA GKYSCRAKNH AAAVNYTTEL IVNVPPRWIL 480
481 EPTDKAFAQG SDAKVECKAD GFPKPQVTWK KAVGDTPGEY KDLKKSDNIR VEEGTLHVDN 540
541 IQKTNEGYYL CEAINGIGSG LSAVIMISVQ APPEFTEKLR NQTARRGEPA VLQCEAKGEK 600
601 PIGILWNMNN MRLDPKNDNR YTIREEILST GVMSSLSIKR TERSDSALFT CVATNA
|
| Detection Method: | |
| Confidence: | 58.522879 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [899-1374] |
1 11 21 31 41 51
| | | | | |
1 FGSDDASINM IVQEVPEMPY ALKVLDKSGR SVQLSWAQPY DGNSPLDRYI IEFKRSRASW 60
61 SEIDRVIVPG HTTEAQVQKL SPATTYNIRI VAENAIGTSQ SSEAVTIITA EEAPSGKPQN 120
121 IKVEPVNQTT MRVTWKPPPR TEWNGEILGY YVGYKLSNTN SSYVFETINF ITEEGKEHNL 180
181 ELQNLRVYTQ YSVVIQAFNK IGAGPLSEEE KQFTAEGTPS QPPSDTACTT LTSQTIRVGW 240
241 VSPPLESANG VIKTYKVVYA PSDEWYDETK RHYKKTASSD TVLHGLKKYT NYTMQVLATT 300
301 AGGDGVRSVP IHCQTEPDVP EAPTDVKALV MGNAAILVSW RPPAQPNGII TQYTVYSKAE 360
361 GAETETKTQK VPHYQMSFEA TELEKNKPYE FWVTASTTIG EGQQSKSIVA MPSDQVPAKI 420
421 ASFDDTFTAT FKEDAKMPCL AVGAPQPEIT WKIKGVEFSA NDRMRVLPDG SLLIKS
|
| Detection Method: | |
| Confidence: | 27.69897 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1375-1595] |
1 11 21 31 41 51
| | | | | |
1 VNRQDAGDYS CHAENSIAKD SITHKLIVLA PPQSPHVTLS ATTTDALTVK LKPHEGDTAP 60
61 LHGYTLHYKP EFGEWETSEV SVDSQKHNIE GLLCGSRYQV YATGFNNIGA GEASDILNTR 120
121 TKGQKPKLPE KPRFIEVSSN SVSLHFKAWK DGGCPMSHFV VESKKRDQIE WNQISNNVKP 180
181 DNNYVVLDLE PATWYNLRIT AHNSAGFTVA EYDFATLTVT G
|
| Detection Method: | |
| Confidence: | 23.30103 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1596-1843] |
1 11 21 31 41 51
| | | | | |
1 GTIAPSRDLP ELSAEDTIRI ILSNLNLVVP VVAALLVIII AIIVICILRS KGNHHKDDVV 60
61 YNQTMGPGAT LDKRRPDLRD ELGYIAPPNR KLPPVPGSNY NTCDRIKRGR GGLRSNHSTW 120
121 DPRRNPNLYE ELKAPPVPMH GNHYGHAHGN AECHYRHPGM EDEICPYATF HLLGFREEMD 180
181 PTKAMNFQTF PHQNGHAGPV PGHAGTMLPP GHPGHVHSRS GSQSMPRANR YQRKNSQGGQ 240
241 SSIYTPAP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1844-2019] |
1 11 21 31 41 51
| | | | | |
1 EYDDPANCAE EDQYRRYTRV NSQGGSLYSG PGPEYDDPAN CAPEEDQYGS QYGGPYGQPY 60
61 DHYGSRGSMG RRSIGSARNP GNGSPEPPPP PPRNHDMSNS SFNDSKESNE ISEAECDRDH 120
121 GPRGNYGAVK RSPQPKDQRT TEEMRKLIER NETGPKQLQL QQANGAGFTA YDTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
