| Protein: | TLL1 |
| Organism: | Homo sapiens |
| Length: | 1013 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TLL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1013] | [1..1013] |
|
|
0.0 | [1..1013] | [1..1013] |
|
|
0.0 | [1..1013] | [1..1013] |
|
|
0.0 | [1..1012] | [1..1012] |
|
|
0.0 | [1..1012] | [1..1012] |
|
|
0.0 | [9..1013] | [2..1008] |
|
|
0.0 | [10..1012] | [3..1007] |
|
|
0.0 | [5..1013] | [7..1022] |
|
Region A: Residues: [1-106] |
1 11 21 31 41 51
| | | | | |
1 MGLGTLSPRM LVWLVASGIV FYGELWVCAG LDYDYTFDGN EEDKTETIDY KDPCKAAVFW 60
61 GDIALDDEDL NIFQIDRTID LTQNPFGNLG HTTGGLGDHA MSKKRG
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.511 | a.112.1 | Description not found. |
| View | Download | 0.344 | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.320 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.313 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.311 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
|
Region A: Residues: [107-361] |
1 11 21 31 41 51
| | | | | |
1 ALYQLIDRIR RIGFGLEQNN TVKGKVPLQF SGQNEKNRVP RAATSRTERI WPGGVIPYVI 60
61 GGNFTGSQRA MFKQAMRHWE KHTCVTFIER SDEESYIVFT YRPCGCCSYV GRRGNGPQAI 120
121 SIGKNCDKFG IVVHELGHVI GFWHEHTRPD RDNHVTIIRE NIQPGQEYNF LKMEPGEVNS 180
181 LGERYDFDSI MHYARNTFSR GMFLDTILPS RDDNGIRPAI GQRTRLSKGD IAQARKLYRC 240
241 PACGETLQES NGNLS
|
| Detection Method: | |
| Confidence: | 40.69897 |
| Match: | 1astA |
| Description: | STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 5.33358263548929 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.99457783001146 | bayes_pls_golite062009 |
| endopeptidase activity | 4.16532996235931 | bayes_pls_golite062009 |
| metallopeptidase activity | 3.94798058866011 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 3.43236442601127 | bayes_pls_golite062009 |
| integrin binding | 2.88756686973769 | bayes_pls_golite062009 |
| hydrolase activity | 2.63109625301237 | bayes_pls_golite062009 |
| exopeptidase activity | 2.07461908743946 | bayes_pls_golite062009 |
| receptor binding | 2.07222569254168 | bayes_pls_golite062009 |
| protein binding | 1.74238091923401 | bayes_pls_golite062009 |
| binding | 1.55761777216628 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.994405248731328 | bayes_pls_golite062009 |
| catalytic activity | 0.891187593353827 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.61233964043845 | bayes_pls_golite062009 |
| zinc ion binding | 0.49304764842799 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.489265029264191 | bayes_pls_golite062009 |
| polysaccharide binding | 0.46452174183235 | bayes_pls_golite062009 |
| serine hydrolase activity | 0.393080846858665 | bayes_pls_golite062009 |
| serine-type peptidase activity | 0.374597710524442 | bayes_pls_golite062009 |
| heparin binding | 0.33626934218604 | bayes_pls_golite062009 |
| interleukin-6 receptor binding | 0.286312555161631 | bayes_pls_golite062009 |
| peptidyl-dipeptidase activity | 0.27229268642689 | bayes_pls_golite062009 |
| growth factor activity | 0.259654587796416 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 0.252655558968584 | bayes_pls_golite062009 |
|
Region A: Residues: [362-769] |
1 11 21 31 41 51
| | | | | |
1 SPGFPNGYPS YTHCIWRVSV TPGEKIVLNF TTMDLYKSSL CWYDYIEVRD GYWRKSPLLG 60
61 RFCGDKLPEV LTSTDSRMWI EFRSSSNWVG KGFAAVYEAI CGGEIRKNEG QIQSPNYPDD 120
121 YRPMKECVWK ITVSESYHVG LTFQSFEIER HDNCAYDYLE VRDGTSENSP LIGRFCGYDK 180
181 PEDIRSTSNT LWMKFVSDGT VNKAGFAANF FKEEDECAKP DRGGCEQRCL NTLGSYQCAC 240
241 EPGYELGPDR RSCEAACGGL LTKLNGTITT PGWPKEYPPN KNCVWQVVAP TQYRISVKFE 300
301 FFELEGNEVC KYDYVEIWSG LSSESKLHGK FCGAEVPEVI TSQFNNMRIE FKSDNTVSKK 360
361 GFKAHFFSDK DECSKDNGGC QHECVNTMGS YMCQCRNGFV LHDNKHDC
|
| Detection Method: | |
| Confidence: | 13.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor binding | 4.33045214660893 | bayes_pls_golite062009 |
| growth factor activity | 3.53240291240997 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 3.49243532917035 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 3.33042410578504 | bayes_pls_golite062009 |
| protein binding | 3.1871213817468 | bayes_pls_golite062009 |
| heparin binding | 3.0535264040722 | bayes_pls_golite062009 |
| polysaccharide binding | 2.79319890241656 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 2.60188936442106 | bayes_pls_golite062009 |
| binding | 2.54996368217395 | bayes_pls_golite062009 |
| pattern binding | 1.7855850180475 | bayes_pls_golite062009 |
| transcription regulator activity | 0.883503304213219 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 0.847169032980225 | bayes_pls_golite062009 |
| transcription factor binding | 0.73345647755411 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.65375278435874 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 0.65339109098708 | bayes_pls_golite062009 |
| carbohydrate binding | 0.37481112933019 | bayes_pls_golite062009 |
| glycoprotein binding | 0.230499048015879 | bayes_pls_golite062009 |
|
Region A: Residues: [770-874] |
1 11 21 31 41 51
| | | | | |
1 KEAECEQKIH SPSGLITSPN WPDKYPSRKE CTWEISATPG HRIKLAFSEF EIEQHQECAY 60
61 DHLEVFDGET EKSPILGRLC GNKIPDPLVA TGNKMFVRFV SDASV
|
| Detection Method: | |
| Confidence: | 31.0 |
| Match: | 1nt0A |
| Description: | Mannose-binding protein associated serine protease 2, MASP2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.17967257091654 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.2470239332285 | bayes_pls_golite062009 |
| endopeptidase activity | 2.22068546360893 | bayes_pls_golite062009 |
| protein binding | 1.66454811956715 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 1.39151268274571 | bayes_pls_golite062009 |
| binding | 1.35566487950264 | bayes_pls_golite062009 |
| metallopeptidase activity | 1.34388258592372 | bayes_pls_golite062009 |
| hydrolase activity | 0.970440417433029 | bayes_pls_golite062009 |
| transcription regulator activity | 0.144877066449329 | bayes_pls_golite062009 |
| receptor activity | 0.125459063751662 | bayes_pls_golite062009 |
| catalytic activity | 0.075748351866431 | bayes_pls_golite062009 |
|
Region A: Residues: [875-1013] |
1 11 21 31 41 51
| | | | | |
1 QRKGFQATHS TECGGRLKAE SKPRDLYSHA QFGDNNYPGQ VDCEWLLVSE RGSRLELSFQ 60
61 TFEVEEEADC GYDYVELFDG LDSTAVGLGR FCGSGPPEEI YSIGDSVLIH FHTDDTINKK 120
121 GFHIRYKSIR YPDTTHTKK
|
| Detection Method: | |
| Confidence: | 4.39794 |
| Match: | 1sfpA |
| Description: | CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.17967257091654 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.2470239332285 | bayes_pls_golite062009 |
| endopeptidase activity | 2.22068546360893 | bayes_pls_golite062009 |
| protein binding | 1.66454811956715 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 1.39151268274571 | bayes_pls_golite062009 |
| binding | 1.35566487950264 | bayes_pls_golite062009 |
| metallopeptidase activity | 1.34388258592372 | bayes_pls_golite062009 |
| hydrolase activity | 0.970440417433029 | bayes_pls_golite062009 |
| transcription regulator activity | 0.144877066449329 | bayes_pls_golite062009 |
| receptor activity | 0.125459063751662 | bayes_pls_golite062009 |
| catalytic activity | 0.075748351866431 | bayes_pls_golite062009 |
