| Protein: | ORC1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 914 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORC1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..914] | [1..914] |
|
|
0.0 | [1..913] | [1..885] |
|
|
9.0E-97 | [84..908] | [151..850] |
|
|
2.0E-96 | [115..908] | [137..861] |
|
|
3.0E-96 | [115..908] | [137..861] |
|
|
2.0E-94 | [98..908] | [139..840] |
|
|
2.0E-89 | [9..911] | [6..801] |
|
Region A: Residues: [1-198] |
1 11 21 31 41 51
| | | | | |
1 MAKTLKDLQG WEIITTDEQG NIIDGGQKRL RRRGAKTEHY LKRSSDGIKL GRGDSVVMHN 60
61 EAAGTYSVYM IQELRLNTLN NVVELWALTY LRWFEVNPLA HYRQFNPDAN ILNRPLNYYN 120
121 KLFSETANKN ELYLTAELAE LQLFNFIRVA NVMDGSKWEV LKGNVDPERD FTVRYICEPT 180
181 GEKFVDINIE DVKAYIKK
|
| Detection Method: |  |
| Confidence: | 25.045757 |
| Match: | PF01426 |
| Description: | BAH domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| structural constituent of chromatin | 5.63555259413678 | bayes_pls_golite062009 |
| DNA replication origin binding | 4.6882205228007 | bayes_pls_golite062009 |
| nucleosomal histone binding | 4.23077815319444 | bayes_pls_golite062009 |
| nucleosome binding | 3.68770692323111 | bayes_pls_golite062009 |
| DNA binding | 3.49504261357874 | bayes_pls_golite062009 |
| nucleic acid binding | 3.45109302518995 | bayes_pls_golite062009 |
| chromatin binding | 2.76371060113086 | bayes_pls_golite062009 |
| binding | 2.47268310088535 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.06404194869726 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.99705816692751 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.92992435554938 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.53908742265394 | bayes_pls_golite062009 |
| structural molecule activity | 1.23840733283098 | bayes_pls_golite062009 |
| histone binding | 0.8857281851882 | bayes_pls_golite062009 |
| protein binding | 0.634982583867058 | bayes_pls_golite062009 |
| catalytic activity | 0.424959044318554 | bayes_pls_golite062009 |
| protein dimerization activity | 0.0647375627009996 | bayes_pls_golite062009 |
|
Region A: Residues: [199-325] |
1 11 21 31 41 51
| | | | | |
1 VEPREAQEYL KDLTLPSKKK EIKRGPQKKD KATQTAQISD AETRATDITD NEDGNEDESS 60
61 DYESPSDIDV SEDMDSGEIS ADELEEEEDE EEDEDEEEKE ARHTNSPRKR GRKIKLGKDD 120
121 IDASVQP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| DNA clamp loader activity | 3.22518920754305 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 3.19273435123154 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| RNA helicase activity | 1.63960194106079 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.61735400124552 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.60404584546501 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.782430219754236 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.6071273686445 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.089234257580272 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
|
Region A: Residues: [326-409] |
1 11 21 31 41 51
| | | | | |
1 PPKKRGRKPK DPSKPRQMLL ISSCRANNTP VIRKFTKKNV ARAKKKYTPF SKRFKSIAAI 60
61 PDLTSLPEFY GNSSELMASR FENK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [410-626] |
1 11 21 31 41 51
| | | | | |
1 LKTTQKHQIV ETIFSKVKKQ LNSSYVKEEI LKSANFQDYL PARENEFASI YLSAYSAIES 60
61 DSATTIYVAG TPGVGKTLTV REVVKELLSS SAQREIPDFL YVEINGLKMV KPTDCYETLW 120
121 NKVSGERLTW AASMESLEFY FKRVPKNKKK TIVVLLDELD AMVTKSQDIM YNFFNWTTYE 180
181 NAKLIVIAVA NTMDLPERQL GNKITSRIGF TRIMFTG
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1e32A_ |
| Description: | Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [627-758] |
1 11 21 31 41 51
| | | | | |
1 YTHEELKNII DLRLKGLNDS FFYVDTKTGN AILIDAAGND TTVKQTLPED VRKVRLRMSA 60
61 DAIEIASRKV ASVSGDARRA LKVCKRAAEI AEKHYMAKHG YGYDGKTVIE DENEEQIYDD 120
121 EDKDLIESNK AK
|
| Detection Method: | |
| Confidence: | 51.39794 |
| Match: | 1e32A_ |
| Description: | Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [759-914] |
1 11 21 31 41 51
| | | | | |
1 DDNDDDDDND GVQTVHITHV MKALNETLNS HVITFMTRLS FTAKLFIYAL LNLMKKNGSQ 60
61 EQELGDIVDE IKLLIEVNGS NKFVMEIAKT LFQQGSDNIS EQLRIISWDF VLNQLLDAGI 120
121 LFKQTMKNDR ICCVKLNISV EEAKRAMNED ETLRNL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
