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View Structure Prediction Details

Protein: UTP13
Organism: Saccharomyces cerevisiae
Length: 817 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP13.

Description E-value Query
Range		 Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
 0.0 [18..707] [865..1491]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
 0.0 [16..761] [1009..1678]

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Predicted Domain #1
Region A:
Residues: [1-131] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLKTSYKGI SLNPIYAGSS AVATVSENGK ILATPVLDEI NIIDLTPGSR KILHKISNED  60
   61 EQEITALKLT PDGQYLTYVS QAQLLKIFHL KTGKVVRSMK ISSPSYILDA DSTSTLLAVG 120
  121 GTDGSIIVVD I

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 3.75
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
4.49063274868921 bayes_pls_golite062009
myosin heavy chain kinase activity 4.33124151198369 bayes_pls_golite062009
actin binding 3.86142918698875 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
myosin II binding 3.56132510021228 bayes_pls_golite062009
GTPase activity 3.23750443966606 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 2.299832037975 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
G-protein-coupled receptor binding 2.10926890165617 bayes_pls_golite062009
transcription regulator activity 2.10348788067437 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
nucleic acid binding 2.00420268007946 bayes_pls_golite062009
dynactin binding 1.99805820148456 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 1.95039718468175 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.53722103498827 bayes_pls_golite062009
DNA binding 1.53482914288832 bayes_pls_golite062009
structural molecule activity 1.47097979074281 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
transcription factor activity 0.897833210520351 bayes_pls_golite062009
kinase activity 0.807669232329985 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.805273887494167 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
transcription activator activity 0.724420384084538 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.634547834947756 bayes_pls_golite062009
transcription repressor activity 0.624053529462119 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
transcription factor binding 0.469377587704245 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
transcription cofactor activity 0.245000508226811 bayes_pls_golite062009
transferase activity 0.217164597663731 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
transcription corepressor activity 0.0676565515282608 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
kinase binding 0.0366162235750993 bayes_pls_golite062009
protein kinase binding 0.00858004043229577 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [132-178] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENGYITHSFK GHGGTISSLK FYGQLNSKIW LLASGDTNGM VKVWDLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.420216
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [179-225] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRKCLHTLQE HTSAVRGLDI IEVPDNDEPS LNLLSGGRDD IINLWDF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.142668
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [226-315] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMKKKCKLLK TLPVNQQVES CGFLKDGDGK RIIYTAGGDA IFQLIDSESG SVLKRTNKPI  60
   61 EELFIIGVLP ILSNSQMFLV LSDQTLQLIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [316-645] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEEDLKNDED TIQVTSSIAG NHGIIADMRY VGPELNKLAL ATNSPSLRII PVPDLSGPEA  60
   61 SLPLDVEIYE GHEDLLNSLD ATEDGLWIAT ASKDNTAIVW RYNENSCKFD IYAKYIGHSA 120
  121 AVTAVGLPNI VSKGYPEFLL TASNDLTIKK WIIPKPTASM DVQIIKVSEY TRHAHEKDIN 180
  181 ALSVSPNDSI FATASYDKTC KIWNLENGEL EATLANHKRG LWDVSFCQYD KLLATSSGDK 240
  241 TVKIWSLDTF SVMKTLEGHT NAVQRCSFIN KQKQLISCGA DGLIKIWDCS SGECLKTLDG 300
  301 HNNRLWALST MNDGDMIVSA DADGVFQFWK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 179.758605
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [646-764] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCTEQEIEEE QEKAKLQVEQ EQSLQNYMSK GDWTNAFLLA MTLDHPMRLF NVLKRALGES  60
   61 RSRQDTEEGK IEVIFNEELD QAISILNDEQ LILLMKRCRD WNTNAKTHTI AQRTIRCIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.218487
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [765-817] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHHNIAKLSE IPGMVKIVDA IIPYTQRHFT RVDNLVEQSY ILDYALVEMD KLF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle