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View Structure Prediction Details

Protein: SMC3
Organism: Saccharomyces cerevisiae
Length: 1230 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMC3.

Description E-value Query
Range
Subject
Range
SMC3_YEAST - Structural maintenance of chromosomes protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
SMC3 - Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells;...
0.0 [1..1230] [1..1230]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
0.0 [52..1093] [867..1936]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
0.0 [52..1093] [870..1939]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
0.0 [52..1095] [870..1941]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
0.0 [52..1093] [869..1938]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [52..1095] [867..1938]

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Predicted Domain #1
Region A:
Residues: [1-50]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYIKRVIIKG FKTYRNETII DNFSPHQNVI IGSNGSGKSN FFAAIRFVLS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1br2A_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 4.51968578934603 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.16381244011837 bayes_pls_golite062009
pyrophosphatase activity 2.13284212711072 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.11265775498161 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.11046854230259 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
hydrolase activity 1.66122526893602 bayes_pls_golite062009
ATPase activity 1.53315090215319 bayes_pls_golite062009
plus-end-directed microtubule motor activity 1.38366133153678 bayes_pls_golite062009
protein-DNA loading ATPase activity 1.29640539057136 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
bubble DNA binding 1.24175604630882 bayes_pls_golite062009
microfilament motor activity 1.20923670094205 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
DNA clamp loader activity 1.12431517057397 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
nucleic acid binding 1.08697924060619 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
DNA binding 0.702147676354075 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
recombinase activity 0.45851158693664 bayes_pls_golite062009
purine nucleotide binding 0.442941451960958 bayes_pls_golite062009
purine ribonucleotide binding 0.440672169804309 bayes_pls_golite062009
ribonucleotide binding 0.440612929099368 bayes_pls_golite062009
nucleotide binding 0.433111366205869 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
centromeric DNA binding 0.322818640526369 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
four-way junction helicase activity 0.26252931460003 bayes_pls_golite062009
exodeoxyribonuclease V activity 0.185603938981231 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [51-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDYSNLKREE RQGLIHQGSG GSVMSASVEI VFHDPDHSMI LPSGVLSRGD DEVTIRRTVG  60
   61 LKKDDYQLND RNVTKGDIVR MLETAGFSMN NPYNIVPQGK IVALTNAKDK ERLQLLEDVV 120
  121 GAKSFEVKLK ASLKKMEETE QKKIQINKEM GELNSKLSEM EQERKELEKY NELERNRKIY 180
  181 QFTLYDRELN EVINQMERLD GDYNNTVYSS EQYIQELDKR EDMIDQVSKK LSSIEASLKI 240
  241 KNATDLQQAK LRESEISQKL TNVNVKIKDV QQQIESNEEQ RNLDSATLKE IKSIIEQRKQ 300
  301 KLSKILPRYQ ELTKEEAMYK LQLASLQQKQ RDLILKKGEY ARFK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [395-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKDERDTWIH SEIEELKSSI QNLNELESQL QMDRTSLRKQ YSAIDEEIEE LIDSING

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.781 a.4.5 "Winged helix" DNA-binding domain
View Download 0.703 a.4.1 Homeodomain-like
View Download 0.765 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.648 a.4.1 Homeodomain-like
View Download 0.631 a.4.1 Homeodomain-like
View Download 0.621 a.4.1 Homeodomain-like
View Download 0.592 a.4.5 "Winged helix" DNA-binding domain
View Download 0.582 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.572 g.2.2 Neurotoxin B-IV
View Download 0.563 a.144.1 PABC (PABP) domain
View Download 0.558 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.555 a.156.1 S13-like H2TH domain
View Download 0.535 a.4.1 Homeodomain-like
View Download 0.530 a.4.5 "Winged helix" DNA-binding domain
View Download 0.529 a.4.5 "Winged helix" DNA-binding domain
View Download 0.529 a.4.5 "Winged helix" DNA-binding domain
View Download 0.527 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.526 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.525 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.517 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.507 a.4.1 Homeodomain-like
View Download 0.504 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.503 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.498 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.487 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.473 a.4.5 "Winged helix" DNA-binding domain
View Download 0.471 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.467 a.4.1 Homeodomain-like
View Download 0.465 a.4.1 Homeodomain-like
View Download 0.457 a.65.1 Annexin
View Download 0.454 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.446 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.446 a.4.1 Homeodomain-like
View Download 0.444 a.4.1 Homeodomain-like
View Download 0.438 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.424 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.410 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.396 a.30.1 ROP protein
View Download 0.395 a.4.5 "Winged helix" DNA-binding domain
View Download 0.376 a.4.5 "Winged helix" DNA-binding domain
View Download 0.375 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.365 a.4.11 RNA polymerase subunit RPB10
View Download 0.363 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.363 a.4.5 "Winged helix" DNA-binding domain
View Download 0.360 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.344 a.4.5 "Winged helix" DNA-binding domain
View Download 0.343 a.4.1 Homeodomain-like
View Download 0.334 a.144.2 Ribosomal protein L20
View Download 0.334 a.74.1 Cyclin-like
View Download 0.334 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.332 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.331 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.329 a.30.1 ROP protein
View Download 0.328 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.326 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.324 a.4.5 "Winged helix" DNA-binding domain
View Download 0.321 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.318 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.318 a.60.2 RuvA domain 2-like
View Download 0.317 a.4.1 Homeodomain-like
View Download 0.315 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.312 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.305 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.304 a.4.1 Homeodomain-like
View Download 0.303 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.300 a.64.1 Saposin
View Download 0.299 a.4.1 Homeodomain-like
View Download 0.297 a.30.1 ROP protein
View Download 0.297 a.4.11 RNA polymerase subunit RPB10
View Download 0.291 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.291 a.4.1 Homeodomain-like
View Download 0.289 a.74.1 Cyclin-like
View Download 0.289 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.287 d.186.1 Head-to-tail joining protein W, gpW
View Download 0.281 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.281 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.280 a.30.1 ROP protein
View Download 0.280 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.279 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.279 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.271 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.270 a.4.11 RNA polymerase subunit RPB10
View Download 0.266 a.4.11 RNA polymerase subunit RPB10
View Download 0.265 a.64.1 Saposin
View Download 0.263 a.144.2 Ribosomal protein L20
View Download 0.262 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.261 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.258 a.145.1 Flagellar transcriptional activator FlhD
View Download 0.258 a.4.5 "Winged helix" DNA-binding domain
View Download 0.256 a.64.2 Bacteriocin AS-48
View Download 0.255 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.251 f.13.1 Family A G protein-coupled receptor-like
View Download 0.251 a.4.5 "Winged helix" DNA-binding domain
View Download 0.251 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.248 a.2.7 tRNA-binding arm
View Download 0.247 a.112.1 Description not found.
View Download 0.246 a.112.1 Description not found.
View Download 0.245 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.237 a.7.6 Ribosomal protein S20
View Download 0.235 a.112.1 Description not found.
View Download 0.233 a.112.1 Description not found.
View Download 0.232 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.231 a.4.5 "Winged helix" DNA-binding domain
View Download 0.231 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.230 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.228 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.226 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.224 a.39.1 EF-hand
View Download 0.222 a.2.7 tRNA-binding arm
View Download 0.218 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.218 a.60.1 SAM/Pointed domain
View Download 0.217 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 a.65.1 Annexin
View Download 0.214 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.211 a.39.1 EF-hand
View Download 0.209 a.60.2 RuvA domain 2-like
View Download 0.206 a.6.1 Putative DNA-binding domain
View Download 0.206 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.204 d.59.1 Ribosomal protein L30p/L7e
View Download 0.203 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.200 a.4.11 RNA polymerase subunit RPB10

Predicted functions:

Term Confidence Notes
binding 3.01984970042125 bayes_pls_golite062009
protein heterodimerization activity 1.35977617500621 bayes_pls_golite062009
DNA secondary structure binding 1.33504054478953 bayes_pls_golite062009
structure-specific DNA binding 1.32955290929194 bayes_pls_golite062009
double-stranded DNA binding 1.12641995595394 bayes_pls_golite062009
protein binding 1.08760961845332 bayes_pls_golite062009
protein dimerization activity 0.966666737816339 bayes_pls_golite062009
nucleic acid binding 0.835977072951553 bayes_pls_golite062009
DNA binding 0.701080369693496 bayes_pls_golite062009
catalytic activity 0.24846317916908 bayes_pls_golite062009
sequence-specific DNA binding 0.0698018163897043 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [452-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDTKGQLEDF DSELIHLKQK LSESLDTRKE LWRKEQKLQT VLETLLSDVN QNQRNVNETM  60
   61 SRSLANGIIN VKEITEKLKI SPESVFGT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [563-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FHIVVDTEET ATLIMNELYR MKGGRVTFIP LNRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.154902
Match: 1gxlA_
Description: Smc hinge domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [540-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGELIKVNDK YKTCAEVIGG NSL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [597-600]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLDS

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [618-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKKIKYEPRF EKAVKHVFG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.154902
Match: 1gxlA_
Description: Smc hinge domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [601-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVKFPSNTTT QIQFTPL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [637-663]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTIVVKDLGQ GLKLAKKHKL NAITLDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.154902
Match: 1gxlA_
Description: Smc hinge domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [664-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRADKRGVLT GGYLDQHKRT RLESLKNLNE SRSQHKKILE ELDFVRNELN DIDTKIDQVN  60
   61 GNIRKVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [731-992]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDRESVLTNI EVYRTSLNTK KNEKLILEES LNAIILKLEK LNTNRTFAQE KLNTFENDLL  60
   61 QEFDSELSKE EKERLESLTK EISAAHNKLN ITSDALEGIT TTIDSLNAEL ESKLIPQEND 120
  121 LESKMSEVGD AFIFGLQDEL KELQLEKESV EKQHENAVLE LGTVQREIES LIAEETNNKK 180
  181 LLEKANNQQR LLLKKLDNFQ KSVEKTMIKK TTLVTRREEL QQRIREIGLL PEDALVNDFS 240
  241 DITSDQLLQR LNDMNTEISG LK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [993-1045]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVNKRAFENF KKFNERRKDL AERASELDES KDSIQDLIVK LKQQKVNAVD STF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.548 a.65.1 Annexin
View Download 0.705 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.637 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.751 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.645 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.526 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.503 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.493 a.4.5 "Winged helix" DNA-binding domain
View Download 0.490 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.455 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.446 a.4.5 "Winged helix" DNA-binding domain
View Download 0.432 a.64.2 Bacteriocin AS-48
View Download 0.416 a.140.3 Rho termination factor, N-terminal domain
View Download 0.414 a.4.1 Homeodomain-like
View Download 0.413 a.30.1 ROP protein
View Download 0.413 a.30.1 ROP protein
View Download 0.385 a.5.2 UBA-like
View Download 0.382 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.379 a.4.5 "Winged helix" DNA-binding domain
View Download 0.377 a.4.5 "Winged helix" DNA-binding domain
View Download 0.376 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.352 a.4.5 "Winged helix" DNA-binding domain
View Download 0.347 d.68.7 R3H domain
View Download 0.336 a.4.5 "Winged helix" DNA-binding domain
View Download 0.336 a.4.1 Homeodomain-like
View Download 0.335 f.13.1 Family A G protein-coupled receptor-like
View Download 0.334 a.4.1 Homeodomain-like
View Download 0.329 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.320 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.311 a.65.1 Annexin
View Download 0.310 a.112.1 Description not found.
View Download 0.304 a.4.1 Homeodomain-like
View Download 0.303 a.4.1 Homeodomain-like
View Download 0.295 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.291 a.138.1 Multiheme cytochromes
View Download 0.280 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.279 a.5.2 UBA-like
View Download 0.277 a.64.2 Bacteriocin AS-48
View Download 0.272 a.17.1 p8-MTCP1
View Download 0.265 a.64.2 Bacteriocin AS-48
View Download 0.265 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.262 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.262 a.158.1 F-box domain
View Download 0.261 a.64.2 Bacteriocin AS-48
View Download 0.260 a.64.2 Bacteriocin AS-48
View Download 0.255 a.64.2 Bacteriocin AS-48
View Download 0.254 a.144.2 Ribosomal protein L20
View Download 0.247 d.58.49 YajQ-like
View Download 0.247 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.240 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.239 a.43.1 Met repressor-like
View Download 0.238 a.5.6 Hypothetical protein MTH1615
View Download 0.234 a.17.1 p8-MTCP1
View Download 0.233 a.65.1 Annexin
View Download 0.232 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.229 a.65.1 Annexin
View Download 0.229 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.228 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.226 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.223 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.222 a.2.7 tRNA-binding arm
View Download 0.219 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.218 d.50.3 PI-Pfui intein middle domain
View Download 0.217 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.216 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.216 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.214 a.3.1 Cytochrome c
View Download 0.213 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.212 a.157.1 Skp1 dimerisation domain-like
View Download 0.211 a.16.1 S15/NS1 RNA-binding domain
View Download 0.210 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.210 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.209 a.138.1 Multiheme cytochromes
View Download 0.209 a.161.1 beta-catenin-interacting protein ICAT
View Download 0.205 a.5.2 UBA-like
View Download 0.204 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.200 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain

Predicted Domain #10
Region A:
Residues: [1046-1230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKVSENFEAV FERLVPRGTA KLIIHRKNDN ANDHDESIDV DMDAESNESQ NGKDSEIMYT  60
   61 GVSISVSFNS KQNEQLHVEQ LSGGQKTVCA IALILAIQMV DPASFYLFDE IDAALDKQYR 120
  121 TAVATLLKEL SKNAQFICTT FRTDMLQVAD KFFRVKYENK ISTVIEVNRE EAIGFIRGSN 180
  181 KFAEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 144.94696
Match: 1e69A_
Description: Smc head domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle