| Protein: | BRR2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 2163 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BRR2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [8..2163] | [3..2129] |
|
|
0.0 | [848..2163] | [1..1299] |
|
|
0.0 | [279..2149] | [63..1923] |
|
|
0.0 | [8..2163] | [10..2162] |
|
|
0.0 | [230..2116] | [16..1919] |
|
Region A: Residues: [1-131] |
1 11 21 31 41 51
| | | | | |
1 MTEHETKDKA KKIREIYRYD EMSNKVLKVD KRFMNTSQNP QRDAEISQPK SMSGRISAKD 60
61 MGQGLCNNIN KGLKENDVAV EKTGKSASLK KIQQHNTILN SSSDFRLHYY PKDPSNVETY 120
121 EQILQWVTEV L
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.585 | N/A | N/A | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.585 | N/A | N/A | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.218 | N/A | N/A | d.198.2 | Arp2/3 complex subunits |
|
Region A: Residues: [132-211] |
1 11 21 31 41 51
| | | | | |
1 GNDIPHDLII GTADIFIRQL KENEENEDGN IEERKEKIQH ELGINIDSLK FNELVKLMKN 60
61 ITDYETHPDN SNKQAVAILA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
|
Region A: Residues: [212-464] |
1 11 21 31 41 51
| | | | | |
1 DDEKSDEEEV TEMSNNANVL GGEINDNEDD DEEYDYNDVE VNSKKKNKRA LPNIENDIIK 60
61 LSDSKTSNIE SVPIYSIDEF FLQRKLRSEL GYKDTSVIQD LSEKILNDIE TLEHNPVALE 120
121 QKLVDLLKFE NISLAEFILK NRSTIFWGIR LAKSTENEIP NLIEKMVAKG LNDLVEQYKF 180
181 RETTHSKREL DSGDDQPQSS EAKRTKFSNP AIPPVIDLEK IKFDESSKLM TVTKVSLPEG 240
241 SFKRVKPQYD EIH
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [465-698] |
1 11 21 31 41 51
| | | | | |
1 IPAPSKPVID YELKEITSLP DWCQEAFPSS ETTSLNPIQS KVFHAAFEGD SNMLICAPTG 60
61 SGKTNIALLT VLKALSHHYN PKTKKLNLSA FKIVYIAPLK ALVQEQVREF QRRLAFLGIK 120
121 VAELTGDSRL SRKQIDETQV LVSTPEKWDI TTRNSNNLAI VELVRLLIID EIHLLHDDRG 180
181 PVLESIVART FWASKYGQEY PRIIGLSATL PNYEDVGRFL RVPKEGLFYF DSSF
|
| Detection Method: | |
| Confidence: | 86.69897 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 4.704140727858 | bayes_pls_golite062009 | |
| structural constituent of ribosome | 3.070470376968 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| RNA binding | 2.29590582680214 | bayes_pls_golite062009 |
| structural molecule activity | 2.08211451183607 | bayes_pls_golite062009 |
| DNA binding | 1.94055378599526 | bayes_pls_golite062009 |
| transcription regulator activity | 1.83584389083042 | bayes_pls_golite062009 |
| RNA helicase activity | 1.42791449104435 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.39335733374328 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.36724390116598 | bayes_pls_golite062009 |
| snRNA binding | 1.20045983086701 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription factor activity | 0.959949409533517 | bayes_pls_golite062009 |
| mRNA binding | 0.76699944561918 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.569910969126728 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.568840867400671 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.568779924702229 | bayes_pls_golite062009 |
| nucleotide binding | 0.564275755355315 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.312659433116074 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| ATP binding | 0.1860481660648 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.152859582615242 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.138615225841109 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0530667986761242 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0482442222493492 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.028470639373934 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0265151533232588 | bayes_pls_golite062009 |
|
Region A: Residues: [699-903] |
1 11 21 31 41 51
| | | | | |
1 RPCPLSQQFC GIKERNSLKK LKAMNDACYE KVLESINEGN QIIVFVHSRK ETSRTATWLK 60
61 NKFAEENITH KLTKNDAGSK QILKTEAANV LDPSLRKLIE SGIGTHHAGL TRSDRSLSED 120
121 LFADGLLQVL VCTATLAWGV NLPAHTVIIK GTDVYSPEKG SWEQLSPQDV LQMLGRAGRP 180
181 RYDTFGEGII ITDQSNVQYY LSVLN
|
| Detection Method: | |
| Confidence: | 86.69897 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural molecule activity | 2.81579918518889 | bayes_pls_golite062009 |
| binding | 2.59063189683655 | bayes_pls_golite062009 |
| protein binding | 1.40069187357924 | bayes_pls_golite062009 |
| cation channel activity | 0.484734651147527 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.448241458604601 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 0.445394181993741 | bayes_pls_golite062009 |
| ligand-gated channel activity | 0.445394181993741 | bayes_pls_golite062009 |
| gated channel activity | 0.437275980569276 | bayes_pls_golite062009 |
| ion channel activity | 0.351655405987795 | bayes_pls_golite062009 |
| actin binding | 0.328787215513486 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.21875054393881 | bayes_pls_golite062009 |
| channel activity | 0.196534845734361 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.196534845734361 | bayes_pls_golite062009 |
|
Region A: Residues: [904-1037] |
1 11 21 31 41 51
| | | | | |
1 QQLPIESQFV SKLVDNLNAE VVAGNIKCRN DAVNWLAYTY LYVRMLASPM LYKVPDISSD 60
61 GQLKKFRESL VHSALCILKE QELVLYDAEN DVIEATDLGN IASSFYINHA SMDVYNRELD 120
121 EHTTQIDLFR IFSM
|
| Detection Method: | |
| Confidence: | 5.69897 |
| Match: | 1d9xA_ |
| Description: | Nucleotide excision repair enzyme UvrB |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 4.704140727858 | bayes_pls_golite062009 | |
| structural constituent of ribosome | 3.070470376968 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| RNA binding | 2.29590582680214 | bayes_pls_golite062009 |
| structural molecule activity | 2.08211451183607 | bayes_pls_golite062009 |
| DNA binding | 1.94055378599526 | bayes_pls_golite062009 |
| transcription regulator activity | 1.83584389083042 | bayes_pls_golite062009 |
| RNA helicase activity | 1.42791449104435 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.39335733374328 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.36724390116598 | bayes_pls_golite062009 |
| snRNA binding | 1.20045983086701 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription factor activity | 0.959949409533517 | bayes_pls_golite062009 |
| mRNA binding | 0.76699944561918 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.569910969126728 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.568840867400671 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.568779924702229 | bayes_pls_golite062009 |
| nucleotide binding | 0.564275755355315 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.312659433116074 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| ATP binding | 0.1860481660648 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.152859582615242 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.138615225841109 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0530667986761242 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0482442222493492 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.028470639373934 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0265151533232588 | bayes_pls_golite062009 |
|
Region A: Residues: [1038-1318] |
1 11 21 31 41 51
| | | | | |
1 SEEFKYVSVR YEEKRELKQL LEKAPIPIRE DIDDPLAKVN VLLQSYFSQL KFEGFALNSD 60
61 IVFIHQNAGR LLRAMFEICL KRGWGHPTRM LLNLCKSATT KMWPTNCPLR QFKTCPVEVI 120
121 KRLEASTVPW GDYLQLETPA EVGRAIRSEK YGKQVYDLLK RFPKMSVTCN AQPITRSVMR 180
181 FNIEIIADWI WDMNVHGSLE PFLLMLEDTD GDSILYYDVL FITPDIVGHE FTLSFTYELK 240
241 QHNQNNLPPN FFLTLISENW WHSEFEIPVS FNGFKLPKKF P
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1319-1784] |
1 11 21 31 41 51
| | | | | |
1 PPTPLLENIS ISTSELGNDD FSEVFEFKTF NKIQSQVFES LYNSNDSVFV GSGKGTGKTA 60
61 MAELALLNHW RQNKGRAVYI NPSGEKIDFL LSDWNKRFSH LAGGKIINKL GNDPSLNLKL 120
121 LAKSHVLLAT PVQFELLSRR WRQRKNIQSL ELMIYDDAHE ISQGVYGAVY ETLISRMIFI 180
181 ATQLEKKIRF VCLSNCLANA RDFGEWAGMT KSNIYNFSPS ERIEPLEINI QSFKDVEHIS 240
241 FNFSMLQMAF EASAAAAGNR NSSSVFLPSR KDCMEVASAF MKFSKAIEWD MLNVEEEQIV 300
301 PYIEKLTDGH LRAPLKHGVG ILYKGMASND ERIVKRLYEY GAVSVLLISK DCSAFACKTD 360
361 EVIILGTNLY DGAEHKYMPY TINELLEMVG LASGNDSMAG KVLILTSHNM KAYYKKFLIE 420
421 PLPTESYLQY IIHDTLNNEI ANSIIQSKQD CVDWFTYSYF YRRIHV
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| 6.55929165712784 | bayes_pls_golite062009 | |
| RNA-dependent ATPase activity | 3.40791872038512 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 3.40070584403887 | bayes_pls_golite062009 |
| RNA helicase activity | 3.25446655280881 | bayes_pls_golite062009 |
| structural molecule activity | 2.80935217964088 | bayes_pls_golite062009 |
| binding | 2.65544526722793 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30172682093249 | bayes_pls_golite062009 |
| helicase activity | 1.87693598354249 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.87127651162653 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.87127651162653 | bayes_pls_golite062009 |
| protein binding | 1.50286160643298 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 0.85500903576568 | bayes_pls_golite062009 |
| ligand-gated channel activity | 0.85500903576568 | bayes_pls_golite062009 |
| cation channel activity | 0.84907542359093 | bayes_pls_golite062009 |
| gated channel activity | 0.79614932073028 | bayes_pls_golite062009 |
| ion channel activity | 0.69968450497191 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.60798225319459 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.554024107811049 | bayes_pls_golite062009 |
| actin binding | 0.54002000529721 | bayes_pls_golite062009 |
| channel activity | 0.52698001588063 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.52698001588063 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 0.410543003164924 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.272496099348536 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.236012840738827 | bayes_pls_golite062009 |
|
Region A: Residues: [1785-1920] |
1 11 21 31 41 51
| | | | | |
1 NPSYYGVRDT SPHGISVFLS NLVETCLNDL VESSFIEIDD TEAEVTAEVN GGDDEATEII 60
61 STLSNGLIAS HYGVSFFTIQ SFVSSLSNTS TLKNMLYVLS TAVEFESVPL RKGDRALLVK 120
121 LSKRLPLRFP EHTSSG
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.314 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.367 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.272 | d.20.1 | UBC-like |
| View | Download | 0.405 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.335 | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.228 | a.39.1 | EF-hand |
| View | Download | 0.224 | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.220 | d.110.4 | SNARE-like |
| View | Download | 0.212 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.210 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.201 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
|
Region A: Residues: [1921-2087] |
1 11 21 31 41 51
| | | | | |
1 SVSFKVFLLL QAYFSRLELP VDFQNDLKDI LEKVVPLINV VVDILSANGY LNATTAMDLA 60
61 QMLIQGVWDV DNPLRQIPHF NNKILEKCKE INVETVYDIM ALEDEERDEI LTLTDSQLAQ 120
121 VAAFVNNYPN VELTYSLNNS DSLISGVKQK ITIQLTRDVE PENLQVT
|
| Detection Method: | |
| Confidence: | 3.154902 |
| Match: | 1jj2X_ |
| Description: | Ribosomal protein L32e |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [2088-2163] |
1 11 21 31 41 51
| | | | | |
1 SEKYPFDKLE SWWLVLGEVS KKELYAIKKV TLNKETQQYE LEFDTPTSGK HNLTIWCVCD 60
61 SYLDADKELS FEINVK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
