| Protein: | RAD16 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 790 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD16.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..790] | [1..790] |
|
|
0.0 | [42..790] | [209..963] |
|
|
0.0 | [42..790] | [107..861] |
|
|
0.0 | [32..788] | [341..1076] |
|
|
0.0 | [8..788] | [416..1130] |
|
|
0.0 | [20..788] | [4..799] |
|
|
0.0 | [4..788] | [94..906] |
|
Region A: Residues: [1-82] |
1 11 21 31 41 51
| | | | | |
1 MQEGGFIRRR RTRSTKKSVN YNELSDDDTA VKNSKTLQLK GNSENVNDSQ DEEYRDDATL 60
61 VKSPDDDDKD FIIDLTGSDK ER
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [83-133] |
1 11 21 31 41 51
| | | | | |
1 TATDENTHAI KNDNDEIIEI KEERDVSDDD EPLTKKRKTT ARKKKKKTST K
|
| Detection Method: | |
| Confidence: | 2.39794 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.98960927712678 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.74178173377247 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 5.13930231819025 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 5.02047466767105 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 2.72222787956584 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 2.60873257753475 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| binding | 2.4974940028864 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.16381244011837 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.11265775498161 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.11046854230259 | bayes_pls_golite062009 |
| endonuclease activity | 1.96689197136388 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| ATPase activity | 1.53315090215319 | bayes_pls_golite062009 |
| ligase activity | 1.31241138156276 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.2935968641033 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.2935353851804 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.29138695385133 | bayes_pls_golite062009 |
| nucleotide binding | 1.28669586915546 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.2539059700735 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.2155186842031 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.117585097627 | bayes_pls_golite062009 |
| nucleic acid binding | 1.08697924060619 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| ATP binding | 0.98146619596929 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.949788783884952 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.931486373329219 | bayes_pls_golite062009 |
| DNA helicase activity | 0.72881469450553 | bayes_pls_golite062009 |
| DNA binding | 0.702147676354075 | bayes_pls_golite062009 |
| motor activity | 0.677658554107 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.5886142102548 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.568457189190858 | bayes_pls_golite062009 |
| protein binding | 0.378225828131122 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.31144582840038 | bayes_pls_golite062009 |
| transcription regulator activity | 0.287777990975748 | bayes_pls_golite062009 |
| DNA strand annealing activity | 0.283577486331079 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.176241137083092 | bayes_pls_golite062009 |
| microtubule motor activity | 0.11674780318211 | bayes_pls_golite062009 |
| kinase activity | 0.0980017568205789 | bayes_pls_golite062009 |
| protein kinase activity | 0.0364322017534667 | bayes_pls_golite062009 |
|
Region A: Residues: [134-368] |
1 11 21 31 41 51
| | | | | |
1 KKSPKVTPYE RNTLRLYEHH PELRNVFTDL KNAPPYVPQR SKQPDGMTIK LLPFQLEGLH 60
61 WLISQEESIY AGGVLADEMG MGKTIQTIAL LMNDLTKSPS LVVAPTVALM QWKNEIEQHT 120
121 KGQLKIYIYH GASRTTDIKD LQGYDVVLTT YAVLESVFRK QNYGFRRKNG LFKQPSVLHN 180
181 IDFYRVILDE AHNIKDRQSN TARAVNNLKT QKRWCLSGTP LQNRIGEMYS LIRFL
|
| Detection Method: | |
| Confidence: | 2.39794 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [369-528] |
1 11 21 31 41 51
| | | | | |
1 NINPFTKYFC TKCDCASKDW KFTDRMHCDH CSHVIMQHTN FFNHFMLKNI QKFGVEGPGL 60
61 ESFNNIQTLL KNIMLRRTKV ERADDLGLPP RIVTVRRDFF NEEEKDLYRS LYTDSKRKYN 120
121 SFVEEGVVLN NYANIFTLIT RMRQLADHPD LVLKRLNNFP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.98960927712678 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.74178173377247 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 5.13930231819025 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 5.02047466767105 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 2.72222787956584 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 2.60873257753475 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| binding | 2.4974940028864 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.16381244011837 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.11265775498161 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.11046854230259 | bayes_pls_golite062009 |
| endonuclease activity | 1.96689197136388 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| ATPase activity | 1.53315090215319 | bayes_pls_golite062009 |
| ligase activity | 1.31241138156276 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.2935968641033 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.2935353851804 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.29138695385133 | bayes_pls_golite062009 |
| nucleotide binding | 1.28669586915546 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.2539059700735 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.2155186842031 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.117585097627 | bayes_pls_golite062009 |
| nucleic acid binding | 1.08697924060619 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| ATP binding | 0.98146619596929 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.949788783884952 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.931486373329219 | bayes_pls_golite062009 |
| DNA helicase activity | 0.72881469450553 | bayes_pls_golite062009 |
| DNA binding | 0.702147676354075 | bayes_pls_golite062009 |
| motor activity | 0.677658554107 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.5886142102548 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.568457189190858 | bayes_pls_golite062009 |
| protein binding | 0.378225828131122 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.31144582840038 | bayes_pls_golite062009 |
| transcription regulator activity | 0.287777990975748 | bayes_pls_golite062009 |
| DNA strand annealing activity | 0.283577486331079 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.176241137083092 | bayes_pls_golite062009 |
| microtubule motor activity | 0.11674780318211 | bayes_pls_golite062009 |
| kinase activity | 0.0980017568205789 | bayes_pls_golite062009 |
| protein kinase activity | 0.0364322017534667 | bayes_pls_golite062009 |
|
Region A: Residues: [529-790] |
1 11 21 31 41 51
| | | | | |
1 GDDIGVVICQ LCNDEAEEPI ESKCHHKFCR LCIKEYVESF MENNNKLTCP VCHIGLSIDL 60
61 SQPALEVDLD SFKKQSIVSR LNMSGKWQSS TKIEALVEEL YKLRSNKRTI KSIVFSQFTS 120
121 MLDLVEWRLK RAGFQTVKLQ GSMSPTQRDE TIKYFMNNIQ CEVFLVSLKA GGVALNLCEA 180
181 SQVFILDPWW NPSVEWQSGD RVHRIGQYRP VKITRFCIED SIEARIIELQ EKKANMIHAT 240
241 INQDEAAISR LTPADLQFLF NN
|
| Detection Method: | |
| Confidence: | 13.522879 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
|
