| Protein: | nep-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 754 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nep-1.
| Description | E-value | Query Range |
Subject Range |
|
|
811.0 | [0..1] | [754..1] |
|
Region A: Residues: [1-754] |
1 11 21 31 41 51
| | | | | |
1 MYTRFGPPIV FLISCYALIL CGTVDALPRA PYFNDDINKT TTTSEDKTVG NTVVEEEKKT 60
61 YTVGDSEGYQ EASRLLQKSL NLSLDPCDDF FEYACRAWVD SHPIPDDLTS YSQFTATREK 120
121 VLAEMRKLYE DNTSIPTSKS IALIKQIYNT CMDTEKHNAV GARDLLEKIK TYGYWPMVHN 180
181 EKWRESTFDL TKLLSNTIQS RDVSVFFDFG PAEDSRNVSR RLLSFDQGSL GLGYSTRDYY 240
241 LDEKKYEKQM KAYRKYTIGK VRYYTEDAGM AVNESKIESD VDEIIAFEKE WAQILVAEED 300
301 RRNYTKLYNV RRFDDLKEYM SIIDWKKLTL STTPFLVHSY LKTNPSIIIS DVEYLQKMNT 360
361 LLQNTDPRIV TNYILLRWAG SWSQEIGKKY EDLQQEFAFQ MYGRKQRQPR WKDCVSSAGG 420
421 KLSYASGSMY VRKYFDANAK NTTLDMITDL QEAFRNMMHA NDWMDAETKK YALEKADQML 480
481 KQIGYPDFIL NDEKLDDWYK GLEGAPEDSF SQLVEKSIQW RNNFYYRRLL EPVNRFEFIS 540
541 SAAVVNAFYS PTRNAIAFPA GILQQPFFDA RFPKALNYGG IGAVIGHEIT HGFDDTGRQF 600
601 DNVGNLRDWW DNTTSSKFNE RTQCIIEQYA DVKLRGTDLR INGKLTQGEN IADNGGIKQA 660
661 FKAYKSYLEK HGGQEARLPQ FESLTNEQLF FVGYAQVWCG AKTPETKTLL LLTDPHSPET 720
721 ARVNTVLTNQ PEFAEAFKCP AGSPMNPTKR CVVW
|
| Detection Method: |  |
| Confidence: | 1000.0 |
| Match: | 1dmtA |
| Description: | Neutral endopeptidase (neprilysin) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 5.33358263548929 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.99457783001146 | bayes_pls_golite062009 |
| bradykinin receptor binding | 4.68498310889748 | bayes_pls_golite062009 |
| endopeptidase activity | 4.16532996235931 | bayes_pls_golite062009 |
| metallopeptidase activity | 3.94798058866011 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 3.43236442601127 | bayes_pls_golite062009 |
| peptidyl-dipeptidase activity | 3.15882456934259 | bayes_pls_golite062009 |
| hydrolase activity | 2.61181165622708 | bayes_pls_golite062009 |
| angiotensin receptor activity | 2.47329778652768 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 2.40931483220122 | bayes_pls_golite062009 |
| exopeptidase activity | 2.07461908743946 | bayes_pls_golite062009 |
| receptor binding | 2.07222569254168 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.71636138555452 | bayes_pls_golite062009 |
| receptor activity | 1.71573921458029 | bayes_pls_golite062009 |
| peptide binding | 1.58227634414618 | bayes_pls_golite062009 |
| protein binding | 1.58118182554863 | bayes_pls_golite062009 |
| binding | 1.55761777216628 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42071856700201 | bayes_pls_golite062009 |
| signal transducer activity | 1.42071856700201 | bayes_pls_golite062009 |
| viral receptor activity | 1.39617252453036 | bayes_pls_golite062009 |
| epoxide hydrolase activity | 1.37998417474643 | bayes_pls_golite062009 |
| ether hydrolase activity | 1.18753073809881 | bayes_pls_golite062009 |
| protein complex binding | 1.16270782056592 | bayes_pls_golite062009 |
| integrin binding | 0.93449223670512 | bayes_pls_golite062009 |
| catalytic activity | 0.891187593353827 | bayes_pls_golite062009 |
| interleukin-6 receptor binding | 0.711782218042781 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.61233964043845 | bayes_pls_golite062009 |
| peptide receptor activity, G-protein coupled | 0.597899738932066 | bayes_pls_golite062009 |
| peptide receptor activity | 0.574641388356132 | bayes_pls_golite062009 |
| zinc ion binding | 0.49304764842799 | bayes_pls_golite062009 |
| hydrolase activity, acting on ether bonds | 0.457157426475929 | bayes_pls_golite062009 |
| serine hydrolase activity | 0.393080846858665 | bayes_pls_golite062009 |
| serine-type peptidase activity | 0.374597710524442 | bayes_pls_golite062009 |
| growth factor activity | 0.259654587796416 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 0.252655558968584 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.21808506596674 | bayes_pls_golite062009 |
| transition metal ion binding | 0.21514043665594 | bayes_pls_golite062009 |
