YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: nas-23
Organism: Caenorhabditis elegans
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-23.

Description E-value Query
Range
Subject
Range
gi|157750650 - gi|157750650|ref|XP_001679037.1| Hypothetical protein CBG13043 [Caenorhabditis briggsae AF16]
gi|39596019, gi|... - gi|39596019|emb|CAE67522.1| Hypothetical protein CBG13043 [Caenorhabditis briggsae], gi|187029048|em...
363.0 [0..1] [537..1]

Back

Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLILVLAG SIGIYGVNLP KIPKLSDLVN PFQQFKLKDI LSTLTALDTP DIAADSAGVS  60
   61 LPKHEYTDRL SSISDLNRSK RDLLFQGDIH LSFEHLSNIV REQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHSRTKRTAF RNAMYPKTIW LPNVPFELHG SLSAKSRSSL VAAMAFWEKH TCVAFKKRTS  60
   61 EKVYLLMSGQ EEGCWSTVGR DEAQGAQILN IGTGCEMFGI TSHEIAHALG LFHEQSRYDR 120
  121 DNYVQIVKSR IAQTNFYDFA VVGKKNMETY GQKYDIGSVM HYRPTEFSLD GGNSIIAKDV 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.1917763812737 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.85190688399485 bayes_pls_golite062009
metallopeptidase activity 3.22757426039234 bayes_pls_golite062009
endopeptidase activity 2.98133341931091 bayes_pls_golite062009
hydrolase activity 2.78513171530601 bayes_pls_golite062009
metalloendopeptidase activity 2.54952091441017 bayes_pls_golite062009
transporter activity 1.28982382930122 bayes_pls_golite062009
binding 1.19918194301835 bayes_pls_golite062009
transmembrane transporter activity 1.0688261398267 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
substrate-specific transporter activity 0.798767221679673 bayes_pls_golite062009
protein binding 0.553658909577001 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543737159152136 bayes_pls_golite062009
exopeptidase activity 0.492456025063956 bayes_pls_golite062009
receptor activity 0.332822250208465 bayes_pls_golite062009
ion transmembrane transporter activity 0.241890854867053 bayes_pls_golite062009
transmembrane receptor activity 0.136560284009247 bayes_pls_golite062009
integrin binding 0.0945964646680701 bayes_pls_golite062009
aminopeptidase activity 0.00533877867882504 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [285-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMQNTMGQFR GPSFIDVAKI NRHYNCEKNC KNKITCLNGG YQHPKNCKIC VCPPGYGGSD  60
   61 CKGIEASSPA K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [356-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CTGVLVAGET QRKFTANIKP NKNAKGIRKC NYHIEAPPGK RIVIIVDSVI GNCVQGCYEE  60
   61 GVELKMYEDK TVTGARFCCK LQKPQTLISQ GNTVPLMLVA GKAQAFVQLR YSTVDGPQNR 120
  121 SPKDGNATSI GVNPFLLEKY QDNSIDSEAI RKEYHIQSDN VNQEDFETLV RSEFIDENTA 180
  181 DI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.19152785302602 bayes_pls_golite062009
peptidase activity 2.03786631670095 bayes_pls_golite062009
protein binding 1.99839937208979 bayes_pls_golite062009
receptor binding 1.94948331803509 bayes_pls_golite062009
transporter activity 1.35573169203175 bayes_pls_golite062009
receptor activity 1.17703206127603 bayes_pls_golite062009
hydrolase activity 1.12447587972667 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.10435298721188 bayes_pls_golite062009
ErbB-2 class receptor binding 1.03966651045249 bayes_pls_golite062009
endopeptidase activity 1.03668892056053 bayes_pls_golite062009
ErbB-3 class receptor binding 1.02450424977847 bayes_pls_golite062009
epidermal growth factor receptor binding 0.71787375735636 bayes_pls_golite062009
metallopeptidase activity 0.623476257655953 bayes_pls_golite062009
metalloendopeptidase activity 0.508669171144608 bayes_pls_golite062009
transcription factor binding 0.30492109086541 bayes_pls_golite062009
growth factor activity 0.190406928940325 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle