YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253593, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	811 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253593, gi|....

Description	E-value	Query Range	Subject Range
gi\|56418613, gi\|... - gi\|56418613\|ref\|YP_145931.1\| ATP-dependent Clp protease ATPase subunit [Geobacillus kaustophilus HTA...	0.0	[1..804]	[1..803]
gi\|89100727, gi\|... - gi\|89100727\|ref\|ZP_01173582.1\| class III stress response-related ATPase [Bacillus sp. NRRL B-14911],...	0.0	[1..811]	[1..810]
gi\|15612666, gi\|... - gi\|15612666\|ref\|NP_240969.1\| class III stress response-related ATPase [Bacillus halodurans C-125], g... gi\|25289933 - pir\|\|G83662 class III stress response-related ATPase clpC [imported] - Bacillus halodurans (strain C...	0.0	[1..808]	[1..809]
gi\|229107768, gi... - gi\|229107768\|ref\|ZP_04237404.1\| Negative regulator of genetic competence [Bacillus cereus Rock1-15],... gi\|228803088, gi... - gi\|228956523\|ref\|ZP_04118319.1\| Negative regulator of genetic competence [Bacillus thuringiensis ser... gi\|228640509, gi... - gi\|229142888\|ref\|ZP_04271329.1\| Negative regulator of genetic competence [Bacillus cereus BDRD-ST24]... gi\|229125599, gi... - gi\|229125599\|ref\|ZP_04254631.1\| Negative regulator of genetic competence [Bacillus cereus BDRD-Cer4]... gi\|29893892, gi\|... - gi\|30018352\|ref\|NP_829983.1\| negative regulator of genetic competence clpC/mecB [Bacillus cereus ATC...	0.0	[1..811]	[1..811]
gi\|51978604, gi\|... - gi\|52145135\|ref\|YP_081693.1\| negative regulator of genetic competence clpC/mecB (ATP-dependent Clp p...	0.0	[1..811]	[1..811]
gi\|89208529, gi\|... - gi\|89208529\|ref\|ZP_01187031.1\| UvrB/UvrC protein:AAA ATPase, central region:Clp, N terminal [Bacillu... gi\|228652302, gi... - gi\|229131089\|ref\|ZP_04260001.1\| Negative regulator of genetic competence [Bacillus cereus BDRD-ST196... gi\|228618333, gi... - gi\|229165070\|ref\|ZP_04292865.1\| Negative regulator of genetic competence [Bacillus cereus AH621], gi...	0.0	[1..811]	[1..811]
gi\|75760630, gi\|... - gi\|75760630\|ref\|ZP_00740659.1\| Negative regulator of genetic competence clpC/mecB [Bacillus thuringi... gi\|228898835, gi... - gi\|228898835\|ref\|ZP_04063117.1\| Negative regulator of genetic competence [Bacillus thuringiensis IBL...	0.0	[1..811]	[1..811]
gi\|89148728, gi\|... - gi\|89203265\|ref\|ZP_01181951.1\| UvrB/UvrC protein:AAA ATPase, central region:Clp, N terminal [Bacillu...	0.0	[1..811]	[1..811]
gi\|52001792, gi\|... - gi\|52783942\|ref\|YP_089771.1\| ClpC [Bacillus licheniformis ATCC 14580], gi\|52346444\|gb\|AAU39078.1\| Cl...	0.0	[1..809]	[1..808]
CLPB_OCEIH - Chaperone protein ClpB OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE83... CLPB_OCEIH - Chaperone protein clpB OS=Oceanobacillus iheyensis GN=clpB PE=3 SV=1	0.0	[1..800]	[1..802]

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Predicted Domain #1

Region A:
Residues: [1-811]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMFGRFTERA QKVLALSQEE AIRIGHNNIG TEHILLGLVR EGEGIAAKAL IALGLSPEKV  60
   61 QKEVEALIGR GTEASQTVHY TPRAKKVIEL SMDEARKLGH SYVGTEHILL GLIREGEGVA 120
  121 ARVLNNLGVS LNKARQQVLQ LLGSNEASSG HQGGSSTNAN TPTLDSLARD LTVVARENRL 180
  181 DPVIGRGKEI QRVIEVLSRR TKNNPVLIGE PGVGKTAIAE GLAQQIVNNE VPETLRDKRV 240
  241 MTLDMGTVVA GTKYRGEFED RLKKVMDEIR QAGNIILFID ELHTLIGAGG AEGAIDASNI 300
  301 LKPSLARGEL QCIGATTLDE YRKYIEKDAA LERRFQPIHV DEPSLDESTQ ILKGLRDRYE 360
  361 AHHRVSITDD AIDAAVKLSD RYITDRFLPD KAIDLIDEAA SKVRLRSYTT PPNLKELEVK 420
  421 LEEIRKEKDA AVQSQEFEKA ASLRDMEQRL REKLEDTKRQ WKEQQGKENS EVTVEDIANV 480
  481 VSTWTRIPVS KLAQTETDKL LNLESILHDR VIGQDEAVVA VAKAVRRARA GLKDPKRPIG 540
  541 SFIFLGPTGV GKTELARALA ESMFGDEDAM IRIDMSEYME KHSTSRLVGS PPGYVGYEEG 600
  601 GQLTEKVRRK PYSVVLLDEV EKAHPDVFNI LLQVLEDGRL TDSKGRTVDF RNTIVIMTSN 660
  661 VGAEALKRNK HLGFNVQDES RDYSDMKGKV MDELKKAFRP EFLNRIDEII VFHMLEKKHI 720
  721 QEIVTLMVNQ LVNRLKEQEI ELHLTEGAIS AIADKGFDRE YGARPLRRAI QKHVEDRLSE 780
  781 ELLKGAIEKG QKVIFDVEGE SFVIHSAEKV K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1qvrA
Description:	Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.54081962055485	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.36181317078971	bayes_pls_golite062009
transmembrane transporter activity	3.29578916194335	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
hydrolase activity	2.55157966585974	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.32451967319952	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.20669061476179	bayes_pls_golite062009
ATPase activity, coupled	2.18396165590908	bayes_pls_golite062009
nucleic acid binding	2.11222585187695	bayes_pls_golite062009
DNA binding	1.7904783386531	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
transcription regulator activity	1.68903321260301	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.67543589693508	bayes_pls_golite062009
substrate-specific transporter activity	1.29730375126024	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
motor activity	0.87979065815418	bayes_pls_golite062009
structural constituent of ribosome	0.860102064846772	bayes_pls_golite062009
structure-specific DNA binding	0.762584163889896	bayes_pls_golite062009
DNA-dependent ATPase activity	0.75383985982414	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
transcription activator activity	0.638755032892208	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
transcription factor activity	0.603758349693077	bayes_pls_golite062009
double-stranded DNA binding	0.49000746592281	bayes_pls_golite062009
protein transmembrane transporter activity	0.46552249844591	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
ion transmembrane transporter activity	0.355466224802969	bayes_pls_golite062009
helicase activity	0.33971254173831	bayes_pls_golite062009
sequence-specific DNA binding	0.334630071828653	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
DNA strand annealing activity	0.270268254152179	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
signal recognition particle binding	0.20866768220789	bayes_pls_golite062009
microtubule motor activity	0.11674780318211	bayes_pls_golite062009
structural molecule activity	0.11239762372728	bayes_pls_golite062009
cation transmembrane transporter activity	0.0254369227200564	bayes_pls_golite062009
ATP-dependent helicase activity	0.0136700590511267	bayes_pls_golite062009
purine NTP-dependent helicase activity	0.0136700590511267	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: