| Protein: | gi|161172191, gi... |
| Organism: | Homo sapiens |
| Length: | 696 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|161172191, gi....
| Description | E-value | Query Range |
Subject Range |
|
|
831.0 | [0..1] | [696..55] |
|
|
831.0 | [0..1] | [696..55] |
|
|
831.0 | [0..1] | [696..55] |
|
|
830.0 | [0..1] | [696..55] |
|
|
827.0 | [0..1] | [696..55] |
|
Region A: Residues: [1-696] |
1 11 21 31 41 51
| | | | | |
1 GICKSSDCIK SAARLIQNMD ATTEPCTDFF KYACGGWLKR NVIPETSSRY GNFDILRDEL 60
61 EVVLKDVLQE PKTEDIVAVQ KAKALYRSCI NESAIDSRGG EPLLKLLPDI YGWPVATENW 120
121 EQKYGASWTA EKAIAQLNSK YGKKVLINLF VGTDDKNSVN HVIHIDQPRL GLPSRDYYEC 180
181 TGIYKEACTA YVDFMISVAR LIRQEERLPI DENQLALEMN KVMELEKEIA NATAKPEDRN 240
241 DPMLLYNKMT LAQIQNNFSL EINGKPFSWL NFTNEIMSTV NISITNEEDV VVYAPEYLTK 300
301 LKPILTKYSA RDLQNLMSWR FIMDLVSSLS RTYKESRNAF RKALYGTTSE TATWRRCANY 360
361 VNGNMENAVG RLYVEAAFAG ESKHVVEDLI AQIREVFIQT LDDLTWMDAE TKKRAEEKAL 420
421 AIKERIGYPD DIVSNDNKLN NEYLELNYKE DEYFENIIQN LKFSQSKQLK KLREKVDKDE 480
481 WISGAAVVNA FYSSGRNQIV FPAGILQPPF FSAQQSNSLN YGGIGMVIGH EITHGFDDNG 540
541 RNFNKDGDLV DWWTQQSASN FKEQSQCMVY QYGNFSWDLA GGQHLNGINT LGENIADNGG 600
601 LGQAYRAYQN YIKKNGEEKL LPGLDLNHKQ LFFLNFAQVW CGTYRPEYAV NSIKTDVHSP 660
661 GNFRIIGTLQ NSAEFSEAFH CRKNSYMNPE KKCRVW
|
| Detection Method: |  |
| Confidence: | 1000.0 |
| Match: | 1dmtA |
| Description: | Neutral endopeptidase (neprilysin) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 5.33358263548929 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.99457783001146 | bayes_pls_golite062009 |
| bradykinin receptor binding | 4.68498310889748 | bayes_pls_golite062009 |
| endopeptidase activity | 4.16532996235931 | bayes_pls_golite062009 |
| metallopeptidase activity | 3.94798058866011 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 3.43236442601127 | bayes_pls_golite062009 |
| peptidyl-dipeptidase activity | 3.15882456934259 | bayes_pls_golite062009 |
| hydrolase activity | 2.61181165622708 | bayes_pls_golite062009 |
| angiotensin receptor activity | 2.47329778652768 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 2.40931483220122 | bayes_pls_golite062009 |
| exopeptidase activity | 2.07461908743946 | bayes_pls_golite062009 |
| receptor binding | 2.07222569254168 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.71636138555452 | bayes_pls_golite062009 |
| receptor activity | 1.71573921458029 | bayes_pls_golite062009 |
| peptide binding | 1.58227634414618 | bayes_pls_golite062009 |
| protein binding | 1.58118182554863 | bayes_pls_golite062009 |
| binding | 1.55761777216628 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42071856700201 | bayes_pls_golite062009 |
| signal transducer activity | 1.42071856700201 | bayes_pls_golite062009 |
| viral receptor activity | 1.39617252453036 | bayes_pls_golite062009 |
| epoxide hydrolase activity | 1.37998417474643 | bayes_pls_golite062009 |
| ether hydrolase activity | 1.18753073809881 | bayes_pls_golite062009 |
| protein complex binding | 1.16270782056592 | bayes_pls_golite062009 |
| integrin binding | 0.93449223670512 | bayes_pls_golite062009 |
| catalytic activity | 0.891187593353827 | bayes_pls_golite062009 |
| interleukin-6 receptor binding | 0.711782218042781 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.61233964043845 | bayes_pls_golite062009 |
| peptide receptor activity, G-protein coupled | 0.597899738932066 | bayes_pls_golite062009 |
| peptide receptor activity | 0.574641388356132 | bayes_pls_golite062009 |
| zinc ion binding | 0.49304764842799 | bayes_pls_golite062009 |
| hydrolase activity, acting on ether bonds | 0.457157426475929 | bayes_pls_golite062009 |
| serine hydrolase activity | 0.393080846858665 | bayes_pls_golite062009 |
| serine-type peptidase activity | 0.374597710524442 | bayes_pls_golite062009 |
| growth factor activity | 0.259654587796416 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 0.252655558968584 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.21808506596674 | bayes_pls_golite062009 |
| transition metal ion binding | 0.21514043665594 | bayes_pls_golite062009 |
