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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.685602980862]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

kinetochore 8.9432E-5 2 60 2 6292
chromosome, centromeric region 1.1171E-4 2 67 2 6292
RAVE complex 9.5344E-4 2 3 1 6292
CBF3 complex 1.2712E-3 2 4 1 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
SCF ubiquitin ligase complex 3.4937E-3 2 11 1 6292
DASH complex 3.811E-3 2 12 1 6292
cullin-RING ubiquitin ligase complex 4.4455E-3 2 14 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of cellular component organization 1.4021E-4 2 75 2 6292
centromere complex assembly 9.5344E-4 2 3 1 6292
kinetochore assembly 9.5344E-4 2 3 1 6292
kinetochore organization 9.5344E-4 2 3 1 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
M phase 2.1762E-3 2 294 2 6292
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.224E-3 2 7 1 6292
protein neddylation 2.224E-3 2 7 1 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 3.4937E-3 2 11 1 6292
regulation of protein complex assembly 3.4937E-3 2 11 1 6292
cell cycle phase 3.5621E-3 2 376 2 6292
regulation of microtubule polymerization or depolymerization 5.3968E-3 2 17 1 6292
regulation of microtubule cytoskeleton organization 5.3968E-3 2 17 1 6292
regulation of microtubule-based process 5.3968E-3 2 17 1 6292
microtubule polymerization or depolymerization 5.7138E-3 2 18 1 6292
regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
cell cycle process 6.0534E-3 2 490 2 6292
regulation of cytoskeleton organization 6.3477E-3 2 20 1 6292
cell cycle 6.95E-3 2 525 2 6292
pH reduction 7.6148E-3 2 24 1 6292
intracellular pH reduction 7.6148E-3 2 24 1 6292
vacuolar acidification 7.6148E-3 2 24 1 6292
regulation of exit from mitosis 7.9314E-3 2 25 1 6292
regulation of cellular pH 7.9314E-3 2 25 1 6292
exit from mitosis 7.9314E-3 2 25 1 6292
regulation of intracellular pH 7.9314E-3 2 25 1 6292
mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292
regulation of pH 9.1975E-3 2 29 1 6292
G2/M transition of mitotic cell cycle 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication origin binding 4.1283E-3 2 13 1 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle