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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.785953982375]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

replication fork 4.3504E-5 2 42 2 6292
delta DNA polymerase complex 9.5344E-4 2 3 1 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
DNA polymerase complex 3.1764E-3 2 10 1 6292
DNA replication factor C complex 3.4937E-3 2 11 1 6292
nuclear replisome 5.7138E-3 2 18 1 6292
replisome 5.7138E-3 2 18 1 6292
nuclear replication fork 6.3477E-3 2 20 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 5.3053E-6 2 15 2 6292
mismatch repair 1.7735E-5 2 27 2 6292
DNA strand elongation 2.3495E-5 2 31 2 6292
DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
DNA-dependent DNA replication 1.678E-4 2 82 2 6292
DNA replication 3.791E-4 2 123 2 6292
DNA repair 9.2646E-4 2 192 2 6292
response to DNA damage stimulus 1.4011E-3 2 236 2 6292
cellular response to stress 2.1173E-3 2 290 2 6292
mutagenesis 2.859E-3 2 9 1 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
base-excision repair 3.811E-3 2 12 1 6292
postreplication repair 5.7138E-3 2 18 1 6292
lagging strand elongation 5.7138E-3 2 18 1 6292
response to stress 6.2277E-3 2 497 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

single-stranded DNA specific exodeoxyribonuclease activity 9.5344E-4 2 3 1 6292
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 9.5344E-4 2 3 1 6292
3'-5'-exodeoxyribonuclease activity 1.9064E-3 2 6 1 6292
DNA clamp loader activity 2.224E-3 2 7 1 6292
protein-DNA loading ATPase activity 2.224E-3 2 7 1 6292
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 2.5415E-3 2 8 1 6292
exodeoxyribonuclease activity 2.859E-3 2 9 1 6292
deoxyribonuclease activity 9.1975E-3 2 29 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle