| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.816908074246] |
| Complex Size: | 2 proteins |
| Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
| HCS1 |
|
|
|
| PRI2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| alpha DNA polymerase:primase complex | 1.0611E-6 | 2 | 7 | 2 | 6292 |
| nuclear replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
| replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
| nuclear replication fork | 9.6001E-6 | 2 | 20 | 2 | 6292 |
| replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
| protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
| nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
| nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
| chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
| chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| lagging strand elongation | 7.7306E-6 | 2 | 18 | 2 | 6292 |
| DNA strand elongation | 2.3495E-5 | 2 | 31 | 2 | 6292 |
| DNA strand elongation involved in DNA replication | 2.3495E-5 | 2 | 31 | 2 | 6292 |
| DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
| DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
| DNA synthesis involved in DNA repair | 1.2712E-3 | 2 | 4 | 1 | 6292 |
| DNA replication, synthesis of RNA primer | 1.5888E-3 | 2 | 5 | 1 | 6292 |
| DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| DNA primase activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
| ATP-dependent 5'-3' DNA helicase activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
| 5'-3' DNA helicase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
| ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |