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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.02472165217]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor A complex 1.5158E-7 2 3 2 6292
nuclear replisome 7.7306E-6 2 18 2 6292
replisome 7.7306E-6 2 18 2 6292
nuclear replication fork 9.6001E-6 2 20 2 6292
chromosome, telomeric region 1.7735E-5 2 27 2 6292
replication fork 4.3504E-5 2 42 2 6292
protein-DNA complex 8.0641E-5 2 57 2 6292
nuclear chromosome part 9.0721E-4 2 190 2 6292
nuclear chromosome 1.3075E-3 2 228 2 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication, synthesis of RNA primer 5.0527E-7 2 5 2 6292
DNA unwinding involved in replication 4.5979E-6 2 14 2 6292
postreplication repair 7.7306E-6 2 18 2 6292
DNA geometric change 9.6001E-6 2 20 2 6292
DNA duplex unwinding 9.6001E-6 2 20 2 6292
double-strand break repair via homologous recombination 1.1672E-5 2 22 2 6292
recombinational repair 1.6421E-5 2 26 2 6292
DNA strand elongation 2.3495E-5 2 31 2 6292
DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
nucleotide-excision repair 3.552E-5 2 38 2 6292
double-strand break repair 8.0641E-5 2 57 2 6292
DNA conformation change 8.3521E-5 2 58 2 6292
DNA-dependent DNA replication 1.678E-4 2 82 2 6292
DNA recombination 3.2544E-4 2 114 2 6292
DNA replication 3.791E-4 2 123 2 6292
DNA repair 9.2646E-4 2 192 2 6292
response to DNA damage stimulus 1.4011E-3 2 236 2 6292
cellular response to stress 2.1173E-3 2 290 2 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
response to stress 6.2277E-3 2 497 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA binding 1.6492E-3 2 256 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle