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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.749770118523]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
POL3
  • replication fork
  • delta DNA polymerase complex
    		•
  • mutagenesis
  • lagging strand elongation
  • base-excision repair
  • leading strand elongation
  • maintenance of fidelity involved in DNA-dependent DNA replication
  • nucleotide-excision repair
  • mismatch repair
  • postreplication repair
    		•
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
    		•
    POL31
  • delta DNA polymerase complex
    		•
  • mutagenesis
  • lagging strand elongation
  • base-excision repair
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • postreplication repair
    		•
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    delta DNA polymerase complex 1.5158E-7 2 3 2 6292
    DNA polymerase complex 2.2737E-6 2 10 2 6292
    nuclear replisome 7.7306E-6 2 18 2 6292
    replisome 7.7306E-6 2 18 2 6292
    nuclear replication fork 9.6001E-6 2 20 2 6292
    replication fork 4.3504E-5 2 42 2 6292
    protein-DNA complex 8.0641E-5 2 57 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mutagenesis 1.819E-6 2 9 2 6292
    base-excision repair 3.3348E-6 2 12 2 6292
    leading strand elongation 5.3053E-6 2 15 2 6292
    postreplication repair 7.7306E-6 2 18 2 6292
    lagging strand elongation 7.7306E-6 2 18 2 6292
    mismatch repair 1.7735E-5 2 27 2 6292
    DNA strand elongation 2.3495E-5 2 31 2 6292
    DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
    nucleotide-excision repair 3.552E-5 2 38 2 6292
    obsolete_biological_process 8.9432E-5 2 60 2 6292
    DNA-dependent DNA replication 1.678E-4 2 82 2 6292
    maintenance of fidelity involved in DNA-dependent DNA replication 3.1786E-4 2 1 1 6292
    DNA replication 3.791E-4 2 123 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    single-stranded DNA specific exodeoxyribonuclease activity 1.5158E-7 2 3 2 6292
    single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 1.5158E-7 2 3 2 6292
    3'-5'-exodeoxyribonuclease activity 7.579E-7 2 6 2 6292
    exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1.4147E-6 2 8 2 6292
    exodeoxyribonuclease activity 1.819E-6 2 9 2 6292
    deoxyribonuclease activity 2.0514E-5 2 29 2 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.8346E-5 2 34 2 6292
    3'-5' exonuclease activity 3.0063E-5 2 35 2 6292
    exonuclease activity 5.2295E-5 2 46 2 6292
    nuclease activity 9.9543E-4 2 199 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle