From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.851945635252] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
RFC4 |
|
|
|
RFC5 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA replication factor C complex | 2.779E-6 | 2 | 11 | 2 | 6292 |
replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
leading strand elongation | 5.3053E-6 | 2 | 15 | 2 | 6292 |
mismatch repair | 1.7735E-5 | 2 | 27 | 2 | 6292 |
DNA strand elongation | 2.3495E-5 | 2 | 31 | 2 | 6292 |
DNA strand elongation involved in DNA replication | 2.3495E-5 | 2 | 31 | 2 | 6292 |
sister chromatid cohesion | 2.5061E-5 | 2 | 32 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
chromosome segregation | 4.1068E-4 | 2 | 128 | 2 | 6292 |
DNA repair | 9.2646E-4 | 2 | 192 | 2 | 6292 |
response to DNA damage stimulus | 1.4011E-3 | 2 | 236 | 2 | 6292 |
cellular response to stress | 2.1173E-3 | 2 | 290 | 2 | 6292 |
cellular response to stimulus | 3.6193E-3 | 2 | 379 | 2 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
response to stress | 6.2277E-3 | 2 | 497 | 2 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein-DNA loading ATPase activity | 1.0611E-6 | 2 | 7 | 2 | 6292 |
DNA clamp loader activity | 1.0611E-6 | 2 | 7 | 2 | 6292 |
DNA-dependent ATPase activity | 7.5032E-5 | 2 | 55 | 2 | 6292 |
ATPase activity, coupled | 5.5711E-4 | 2 | 149 | 2 | 6292 |
ATPase activity | 1.1194E-3 | 2 | 211 | 2 | 6292 |
DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 |
nucleoside-triphosphatase activity | 2.7262E-3 | 2 | 329 | 2 | 6292 |
hydrolase activity, acting on acid anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
pyrophosphatase activity | 3.1391E-3 | 2 | 353 | 2 | 6292 |