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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc55. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein phosphatase type 2A complex 4.8197E-10 3 6 3 6292
protein serine/threonine phosphatase complex 1.6387E-8 3 17 3 6292
cellular bud tip 2.4051E-4 3 57 2 6292
cellular bud neck 1.2346E-3 3 129 2 6292
cellular bud 2.0398E-3 3 166 2 6292
site of polarized growth 2.089E-3 3 168 2 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitotic cell cycle spindle assembly checkpoint 3.2051E-8 3 21 3 6292
negative regulation of mitotic metaphase/anaphase transition 3.2051E-8 3 21 3 6292
spindle assembly checkpoint 3.2051E-8 3 21 3 6292
negative regulation of nuclear division 3.2051E-8 3 21 3 6292
negative regulation of mitosis 3.2051E-8 3 21 3 6292
negative regulation of cell cycle 3.7112E-8 3 22 3 6292
regulation of mitotic metaphase/anaphase transition 5.5427E-8 3 25 3 6292
mitotic cell cycle spindle checkpoint 5.5427E-8 3 25 3 6292
spindle checkpoint 5.5427E-8 3 25 3 6292
mitotic cell cycle checkpoint 7.8947E-8 3 28 3 6292
protein amino acid dephosphorylation 7.8947E-8 3 28 3 6292
negative regulation of cellular component organization 8.8056E-8 3 29 3 6292
regulation of nuclear division 8.8056E-8 3 29 3 6292
negative regulation of organelle organization 8.8056E-8 3 29 3 6292
regulation of mitosis 8.8056E-8 3 29 3 6292
negative regulation of cell cycle process 1.1953E-7 3 32 3 6292
budding cell bud growth 1.4421E-7 3 34 3 6292
mitotic metaphase/anaphase transition 1.8725E-7 3 37 3 6292
dephosphorylation 2.3809E-7 3 40 3 6292
regulation of organelle organization 5.3258E-7 3 52 3 6292
cell cycle checkpoint 7.4359E-7 3 58 3 6292
actin filament organization 1.2077E-6 3 68 3 6292
regulation of mitotic cell cycle 1.3774E-6 3 71 3 6292
regulation of cellular component organization 1.6273E-6 3 75 3 6292
regulation of cell cycle process 2.0561E-6 3 81 3 6292
asexual reproduction 2.8311E-6 3 90 3 6292
cell budding 2.8311E-6 3 90 3 6292
mitosis 4.3885E-6 3 104 3 6292
nuclear division 4.6491E-6 3 106 3 6292
organelle fission 5.6424E-6 3 113 3 6292
actin cytoskeleton organization 5.6424E-6 3 113 3 6292
actin filament-based process 6.2688E-6 3 117 3 6292
M phase of mitotic cell cycle 8.2267E-6 3 128 3 6292
regulation of cell cycle 8.8236E-6 3 131 3 6292
growth 1.1992E-5 3 145 3 6292
cell division 1.1992E-5 3 145 3 6292
signal transduction 3.8812E-5 3 214 3 6292
signal transmission 4.0476E-5 3 217 3 6292
signaling process 4.0476E-5 3 217 3 6292
reproduction of a single-celled organism 4.0476E-5 3 217 3 6292
phosphorus metabolic process 4.7603E-5 3 229 3 6292
phosphate metabolic process 4.7603E-5 3 229 3 6292
cytoskeleton organization 4.8867E-5 3 231 3 6292
negative regulation of cellular process 6.2006E-5 3 250 3 6292
signaling 6.3512E-5 3 252 3 6292
negative regulation of biological process 6.4274E-5 3 253 3 6292
mitotic cell cycle 6.5817E-5 3 255 3 6292
M phase 1.0103E-4 3 294 3 6292
reproduction 1.4044E-4 3 328 3 6292
post-translational protein modification 1.8121E-4 3 357 3 6292
cell cycle phase 2.118E-4 3 376 3 6292
translation 2.118E-4 3 376 3 6292
cell cycle process 4.6964E-4 3 490 3 6292
protein modification process 4.9605E-4 3 499 3 6292
cell cycle 5.7787E-4 3 525 3 6292
macromolecule modification 7.3601E-4 3 569 3 6292
negative regulation of exit from mitosis 1.9063E-3 3 4 1 6292
regulation of cellular process 2.0181E-3 3 796 3 6292
regulation of biological process 2.2389E-3 3 824 3 6292
cellular protein metabolic process 4.9618E-3 3 1074 3 6292
organelle organization 5.734E-3 3 1127 3 6292
protein metabolic process 5.8726E-3 3 1136 3 6292
cellular macromolecule biosynthetic process 6.7003E-3 3 1187 3 6292
macromolecule biosynthetic process 6.7343E-3 3 1189 3 6292
biological regulation 7.1507E-3 3 1213 3 6292
gene expression 8.4626E-3 3 1283 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein serine/threonine phosphatase activity 4.9138E-5 3 26 2 6292
phosphoprotein phosphatase activity 1.3628E-4 3 43 2 6292
phosphatase activity 5.6195E-4 3 87 2 6292
phosphoric ester hydrolase activity 7.7251E-4 3 102 2 6292
protein phosphatase type 2A regulator activity 1.9063E-3 3 4 1 6292
hydrolase activity, acting on ester bonds 8.4714E-3 3 341 2 6292

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