YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc55. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 5 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • PPH21
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • PPH22
  • condensed nuclear chromosome, centromeric region
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • YCK2
  • cellular bud neck
  • mating projection
  • plasma membrane
  • response to glucose stimulus
  • cell morphogenesis
  • cytokinesis
  • protein amino acid phosphorylation
  • endocytosis
  • casein kinase I activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 2A complex 1.1493E-12 5 6 4 6292
    protein serine/threonine phosphatase complex 1.821E-10 5 17 4 6292
    cellular bud neck 8.1715E-5 5 129 3 6292
    cellular bud 1.7347E-4 5 166 3 6292
    site of polarized growth 1.7977E-4 5 168 3 6292
    cell projection 5.8536E-4 5 49 2 6292
    mating projection 5.8536E-4 5 49 2 6292
    cellular bud tip 7.924E-4 5 57 2 6292
    protein complex 4.5433E-3 5 1137 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mitotic cell cycle spindle assembly checkpoint 4.5768E-10 5 21 4 6292
    negative regulation of nuclear division 4.5768E-10 5 21 4 6292
    negative regulation of mitosis 4.5768E-10 5 21 4 6292
    negative regulation of mitotic metaphase/anaphase transition 4.5768E-10 5 21 4 6292
    spindle assembly checkpoint 4.5768E-10 5 21 4 6292
    negative regulation of cell cycle 5.5932E-10 5 22 4 6292
    spindle checkpoint 9.6687E-10 5 25 4 6292
    regulation of mitotic metaphase/anaphase transition 9.6687E-10 5 25 4 6292
    mitotic cell cycle spindle checkpoint 9.6687E-10 5 25 4 6292
    mitotic cell cycle checkpoint 1.5644E-9 5 28 4 6292
    protein amino acid dephosphorylation 1.5644E-9 5 28 4 6292
    negative regulation of cellular component organization 1.8144E-9 5 29 4 6292
    regulation of nuclear division 1.8144E-9 5 29 4 6292
    negative regulation of organelle organization 1.8144E-9 5 29 4 6292
    regulation of mitosis 1.8144E-9 5 29 4 6292
    negative regulation of cell cycle process 2.7461E-9 5 32 4 6292
    budding cell bud growth 3.5406E-9 5 34 4 6292
    mitotic metaphase/anaphase transition 5.0403E-9 5 37 4 6292
    cell division 6.0718E-9 5 145 5 6292
    dephosphorylation 6.9718E-9 5 40 4 6292
    regulation of organelle organization 2.0621E-8 5 52 4 6292
    cell cycle checkpoint 3.2292E-8 5 58 4 6292
    phosphorus metabolic process 6.1212E-8 5 229 5 6292
    phosphate metabolic process 6.1212E-8 5 229 5 6292
    actin filament organization 6.1904E-8 5 68 4 6292
    regulation of mitotic cell cycle 7.3829E-8 5 71 4 6292
    regulation of cellular component organization 9.2307E-8 5 75 4 6292
    regulation of cell cycle process 1.2626E-7 5 81 4 6292
    cell budding 1.9368E-7 5 90 4 6292
    asexual reproduction 1.9368E-7 5 90 4 6292
    mitosis 3.479E-7 5 104 4 6292
    nuclear division 3.7577E-7 5 106 4 6292
    organelle fission 4.8661E-7 5 113 4 6292
    actin cytoskeleton organization 4.8661E-7 5 113 4 6292
    actin filament-based process 5.6E-7 5 117 4 6292
    post-translational protein modification 5.7263E-7 5 357 5 6292
    M phase of mitotic cell cycle 8.0467E-7 5 128 4 6292
    regulation of cell cycle 8.8342E-7 5 131 4 6292
    growth 1.3296E-6 5 145 4 6292
    protein modification process 3.0798E-6 5 499 5 6292
    macromolecule modification 5.9519E-6 5 569 5 6292
    signal transduction 6.3369E-6 5 214 4 6292
    signal transmission 6.6998E-6 5 217 4 6292
    signaling process 6.6998E-6 5 217 4 6292
    reproduction of a single-celled organism 6.6998E-6 5 217 4 6292
    cytoskeleton organization 8.6023E-6 5 231 4 6292
    negative regulation of cellular process 1.1795E-5 5 250 4 6292
    signaling 1.2176E-5 5 252 4 6292
    negative regulation of biological process 1.237E-5 5 253 4 6292
    mitotic cell cycle 1.2765E-5 5 255 4 6292
    M phase 2.2511E-5 5 294 4 6292
    reproduction 3.4791E-5 5 328 4 6292
    cell cycle phase 5.9837E-5 5 376 4 6292
    translation 5.9837E-5 5 376 4 6292
    cellular protein metabolic process 1.4379E-4 5 1074 5 6292
    cell cycle process 1.7059E-4 5 490 4 6292
    protein metabolic process 1.9046E-4 5 1136 5 6292
    cell cycle 2.2393E-4 5 525 4 6292
    G1/S transition of mitotic cell cycle 6.0956E-4 5 50 2 6292
    cellular component organization 1.0001E-3 5 1582 5 6292
    regulation of cellular process 1.1441E-3 5 796 4 6292
    regulation of biological process 1.3089E-3 5 824 4 6292
    interphase of mitotic cell cycle 2.2823E-3 5 97 2 6292
    interphase 2.2823E-3 5 97 2 6292
    negative regulation of exit from mitosis 3.1756E-3 5 4 1 6292
    response to monosaccharide stimulus 3.9682E-3 5 5 1 6292
    response to glucose stimulus 3.9682E-3 5 5 1 6292
    response to hexose stimulus 3.9682E-3 5 5 1 6292
    organelle organization 4.3919E-3 5 1127 4 6292
    response to carbohydrate stimulus 4.7604E-3 5 6 1 6292
    cellular macromolecule biosynthetic process 5.3579E-3 5 1187 4 6292
    macromolecule biosynthetic process 5.3925E-3 5 1189 4 6292
    biological regulation 5.8209E-3 5 1213 4 6292
    cellular macromolecule metabolic process 6.2991E-3 5 2285 5 6292
    gene expression 7.2106E-3 5 1283 4 6292
    macromolecule metabolic process 7.2329E-3 5 2349 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein serine/threonine phosphatase activity 6.2313E-7 5 26 3 6292
    phosphoprotein phosphatase activity 2.9457E-6 5 43 3 6292
    phosphatase activity 2.5034E-5 5 87 3 6292
    phosphoric ester hydrolase activity 4.0406E-5 5 102 3 6292
    metal ion binding 7.3776E-4 5 55 2 6292
    ion binding 7.6484E-4 5 56 2 6292
    cation binding 7.6484E-4 5 56 2 6292
    hydrolase activity, acting on ester bonds 1.4541E-3 5 341 3 6292
    casein kinase I activity 3.1756E-3 5 4 1 6292
    protein phosphatase type 2A regulator activity 3.1756E-3 5 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle