YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Arc40. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARC18
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • actin filament organization
  • structural constituent of cytoskeleton
  • ARC35
  • cytosol
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • microtubule cytoskeleton organization
  • actin cytoskeleton organization
  • structural molecule activity
  • ARC40
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • actin nucleation
  • actin filament organization
  • structural constituent of cytoskeleton
  • ARP2
  • mitochondrion
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • actin filament organization
  • ATP binding
  • actin binding
  • structural constituent of cytoskeleton
  • ARP3
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • actin filament organization
  • ATP binding
  • actin binding
  • structural constituent of cytoskeleton
  • NIP1
  • multi-eIF complex
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • NOP4
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • POB3
  • nucleus
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
  • chromatin remodeling
  • DNA-dependent DNA replication
  • chromatin assembly or disassembly
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • chromatin binding
  • SSZ1
  • cytoplasm
  • regulation of translational fidelity
  • translation
  • unfolded protein binding
  • YLR241W
  • cellular_component
  • biological_process
  • molecular_function
  • YNL040W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Arp2/3 protein complex 1.1806E-13 11 7 5 6292
    actin cytoskeleton 1.7326E-7 11 85 5 6292
    cytoskeletal part 1.2506E-5 11 201 5 6292
    cytoskeleton 1.7767E-5 11 216 5 6292
    non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    intracellular non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    protein complex 1.0346E-3 11 1137 7 6292
    FACT complex 3.4937E-3 11 2 1 6292
    macromolecular complex 9.4307E-3 11 1635 7 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mitochondrion inheritance 6.5602E-10 11 29 5 6292
    mitochondrion distribution 6.5602E-10 11 29 5 6292
    mitochondrion localization 7.866E-10 11 30 5 6292
    organelle inheritance 5.9279E-9 11 44 5 6292
    organelle localization 1.7326E-7 11 85 5 6292
    actin cytoskeleton organization 7.2491E-7 11 113 5 6292
    actin filament-based process 8.6252E-7 11 117 5 6292
    mitochondrion organization 3.5998E-6 11 156 5 6292
    actin filament organization 3.8902E-6 11 68 4 6292
    cytoskeleton organization 2.4628E-5 11 231 5 6292
    cellular localization 2.999E-3 11 643 5 6292
    actin nucleation 5.2364E-3 11 3 1 6292
    organelle organization 6.6286E-3 11 1127 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of cytoskeleton 1.4177E-6 11 53 4 6292
    structural molecule activity 1.5556E-4 11 339 5 6292
    actin binding 5.731E-4 11 21 2 6292
    ATP binding 7.5106E-4 11 24 2 6292
    adenyl ribonucleotide binding 8.1559E-4 11 25 2 6292
    adenyl nucleotide binding 1.177E-3 11 30 2 6292
    purine nucleoside binding 1.2569E-3 11 31 2 6292
    nucleoside binding 1.3395E-3 11 32 2 6292
    ribonucleotide binding 2.1955E-3 11 41 2 6292
    purine ribonucleotide binding 2.1955E-3 11 41 2 6292
    purine nucleotide binding 3.5132E-3 11 52 2 6292
    nucleotide binding 4.5031E-3 11 59 2 6292
    cytoskeletal protein binding 4.5031E-3 11 59 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle