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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

proton-transporting V-type ATPase, V1 domain 6.8252E-16 5 8 5 6292
vacuolar proton-transporting V-type ATPase, V1 domain 6.8252E-16 5 8 5 6292
proton-transporting two-sector ATPase complex, catalytic domain 1.5686E-14 5 13 5 6292
vacuolar proton-transporting V-type ATPase complex 3.66E-14 5 15 5 6292
proton-transporting V-type ATPase complex 3.66E-14 5 15 5 6292
proton-transporting two-sector ATPase complex 3.9566E-12 5 35 5 6292
fungal-type vacuole membrane 1.9633E-10 5 74 5 6292
vacuolar membrane 1.7107E-9 5 113 5 6292
vacuolar part 2.4229E-9 5 121 5 6292
fungal-type vacuole 9.3817E-9 5 158 5 6292
lytic vacuole 9.3817E-9 5 158 5 6292
storage vacuole 9.3817E-9 5 158 5 6292
vacuole 3.8596E-8 5 209 5 6292
membrane part 1.2719E-5 5 662 5 6292
organelle membrane 1.5885E-5 5 692 5 6292
protein complex 1.913E-4 5 1137 5 6292
membrane 2.4854E-4 5 1198 5 6292
macromolecular complex 1.1794E-3 5 1635 5 6292
organelle part 6.2578E-3 5 2282 5 6292
intracellular organelle part 6.2578E-3 5 2282 5 6292
cytoplasmic part 9.5281E-3 5 2482 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

vacuolar acidification 5.1803E-13 5 24 5 6292
pH reduction 5.1803E-13 5 24 5 6292
intracellular pH reduction 5.1803E-13 5 24 5 6292
regulation of intracellular pH 6.4754E-13 5 25 5 6292
regulation of cellular pH 6.4754E-13 5 25 5 6292
regulation of pH 1.4474E-12 5 29 5 6292
cellular monovalent inorganic cation homeostasis 3.3913E-12 5 34 5 6292
monovalent inorganic cation homeostasis 6.1176E-12 5 38 5 6292
cellular cation homeostasis 1.1769E-9 5 105 5 6292
cation homeostasis 1.4239E-9 5 109 5 6292
cellular chemical homeostasis 2.226E-9 5 119 5 6292
cellular ion homeostasis 2.226E-9 5 119 5 6292
cellular homeostasis 2.3227E-9 5 120 5 6292
chemical homeostasis 2.6335E-9 5 123 5 6292
ion homeostasis 2.6335E-9 5 123 5 6292
homeostatic process 1.1204E-6 5 408 5 6292
regulation of biological quality 5.0653E-6 5 551 5 6292
biological regulation 2.6452E-4 5 1213 5 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

proton-transporting ATPase activity, rotational mechanism 1.5686E-14 5 13 5 6292
cation-transporting ATPase activity 5.3237E-14 5 16 5 6292
ATPase activity, coupled to transmembrane movement of ions 1.4474E-12 5 29 5 6292
hydrogen ion transmembrane transporter activity 3.8544E-11 5 54 5 6292
primary active transmembrane transporter activity 4.2399E-11 5 55 5 6292
P-P-bond-hydrolysis-driven transmembrane transporter activity 4.2399E-11 5 55 5 6292
ATPase activity, coupled to transmembrane movement of substances 4.2399E-11 5 55 5 6292
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 4.2399E-11 5 55 5 6292
monovalent inorganic cation transmembrane transporter activity 6.1017E-11 5 59 5 6292
ATPase activity, coupled to movement of substances 6.1017E-11 5 59 5 6292
inorganic cation transmembrane transporter activity 9.6539E-10 5 101 5 6292
cation transmembrane transporter activity 2.1324E-9 5 118 5 6292
active transmembrane transporter activity 2.4229E-9 5 121 5 6292
ion transmembrane transporter activity 6.2872E-9 5 146 5 6292
ATPase activity, coupled 6.97E-9 5 149 5 6292
ATPase activity 4.0498E-8 5 211 5 6292
substrate-specific transmembrane transporter activity 1.3272E-7 5 267 5 6292
transmembrane transporter activity 2.6369E-7 5 306 5 6292
nucleoside-triphosphatase activity 3.7972E-7 5 329 5 6292
substrate-specific transporter activity 4.2214E-7 5 336 5 6292
hydrolase activity, acting on acid anhydrides 5.4108E-7 5 353 5 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.4108E-7 5 353 5 6292
pyrophosphatase activity 5.4108E-7 5 353 5 6292
transporter activity 1.0663E-6 5 404 5 6292
hydrolase activity 6.3032E-5 5 911 5 6292
catalytic activity 4.6443E-3 5 2150 5 6292

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