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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AIM3
  • membrane raft
  • biological_process
  • molecular_function
  • BAR1
  • cell wall-bounded periplasmic space
  • protein catabolic process
  • aspartic-type endopeptidase activity
  • COA4
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • GYL1
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud
  • cytoplasm
  • cellular bud neck
  • mitochondrion
  • Golgi-associated vesicle
  • plasma membrane
  • ER to Golgi vesicle-mediated transport
  • regulation of exocytosis
  • protein binding
  • GYP5
  • incipient cellular bud site
  • cellular bud tip
  • soluble fraction
  • cellular bud neck
  • cytosol
  • Golgi-associated vesicle
  • plasma membrane
  • ER to Golgi vesicle-mediated transport
  • vesicle-mediated transport
  • Rab GTPase activator activity
  • HNT1
  • nucleus
  • cytoplasm
  • nucleotide metabolic process
  • nucleotide binding
  • hydrolase activity
  • KIN2
  • membrane fraction
  • plasma membrane
  • exocytosis
  • protein kinase activity
  • MEF2
  • mitochondrion
  • translational elongation
  • translation elongation factor activity
  • NCP1
  • mitochondrion
  • microsome
  • mitochondrial outer membrane
  • electron transport
  • ergosterol biosynthetic process
  • electron carrier activity
  • PCL10
  • cyclin-dependent protein kinase holoenzyme complex
  • regulation of glycogen biosynthetic process
  • regulation of glycogen catabolic process
  • cyclin-dependent protein kinase regulator activity
  • PRP28
  • U5 snRNP
  • spliceosomal complex
  • RNA splicing
  • mRNA processing
  • cis assembly of pre-catalytic spliceosome
  • ATP-dependent RNA helicase activity
  • RVS161
  • mating projection
  • membrane raft
  • actin cortical patch
  • bipolar cellular bud site selection
  • response to osmotic stress
  • endocytosis
  • cytoskeletal protein binding
  • RVS167
  • actin cortical patch
  • vesicle-mediated transport
  • bipolar cellular bud site selection
  • response to osmotic stress
  • endocytosis
  • cytoskeletal protein binding
  • SAE2
  • nucleus
  • cytoplasm
  • meiotic DNA double-strand break processing
  • molecular_function
  • SLK19
  • spindle
  • condensed nuclear chromosome kinetochore
  • kinetochore
  • mitotic spindle organization in nucleus
  • meiosis
  • molecular_function
  • TIM21
  • mitochondrial inner membrane presequence translocase complex
  • mitochondrion
  • protein import into mitochondrial matrix
  • molecular_function
  • VPS15
  • mitochondrion
  • Golgi membrane
  • protein retention in Golgi apparatus
  • telomere maintenance
  • inositol lipid-mediated signaling
  • protein amino acid phosphorylation
  • protein targeting to vacuole
  • protein serine/threonine kinase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    membrane raft 1.9058E-4 17 8 2 6292
    Golgi apparatus part 3.6959E-3 17 119 3 6292
    cell fraction 4.6392E-3 17 129 3 6292
    Golgi-associated vesicle 5.0459E-3 17 40 2 6292
    actin cortical patch 5.2962E-3 17 41 2 6292
    incipient cellular bud site 6.3538E-3 17 45 2 6292
    membrane 7.9917E-3 17 1198 8 6292
    cortical actin cytoskeleton 8.4163E-3 17 52 2 6292
    cortical cytoskeleton 8.4163E-3 17 52 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    vesicle-mediated transport 1.6136E-3 17 340 5 6292
    bipolar cellular bud site selection 3.6639E-3 17 34 2 6292
    cis assembly of pre-catalytic spliceosome 5.3968E-3 17 2 1 6292
    exocytosis 6.6321E-3 17 46 2 6292
    regulation of exocytosis 8.0849E-3 17 3 1 6292
    regulation of secretion 8.0849E-3 17 3 1 6292
    nuclear mRNA cis splicing, via spliceosome 8.0849E-3 17 3 1 6292
    meiotic DNA double-strand break processing 8.0849E-3 17 3 1 6292
    secretion 9.0541E-3 17 54 2 6292
    secretion by cell 9.0541E-3 17 54 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle