YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. The cellular process by which a complex containing RNA and proteins is synthesized, aggregates, and bonds together. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cis assembly of pre-catalytic spliceosome
Acc: GO:0000354
Aspect: Biological Process
Desc: Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
Synonyms:
  • GO:0000361
  • GO:0000360
  • spliceosomal A2-1 complex biosynthesis
  • spliceosomal B1 complex biosynthesis
  • formation of spliceosomal B1 complex
  • spliceosomal B1 complex formation
  • cis assembly of U2-type pre-catalytic spliceosome
  • formation of spliceosomal A2-1 complex
  • cis assembly of U12-type pre-catalytic spliceosome
  • spliceosomal A2-1 complex formation
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000354 - cis assembly of pre-catalytic spliceosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle