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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 510.180.20
Complex Size: 5 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RAD51
  • nuclear chromosome
  • condensed nuclear chromosome
  • meiotic joint molecule formation
  • reciprocal meiotic recombination
  • heteroduplex formation
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • strand invasion
  • DNA-dependent ATPase activity
  • recombinase activity
  • RAD52
  • nucleus
  • nuclear chromosome
  • meiotic DNA recombinase assembly
  • double-strand break repair via break-induced replication
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • double-strand break repair via synthesis-dependent strand annealing
  • DNA recombinase assembly
  • postreplication repair
  • DNA strand annealing activity
  • recombinase activity
  • RAD54
  • nucleus
  • chromatin remodeling
  • heteroduplex formation
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • double-strand break repair via synthesis-dependent strand annealing
  • DNA-dependent ATPase activity
  • DNA topoisomerase activity
  • RAD55
  • nucleus
  • meiotic DNA recombinase assembly
  • heteroduplex formation
  • double-strand break repair via single-strand annealing
  • DNA recombinase assembly
  • DNA-dependent ATPase activity
  • protein heterodimerization activity
  • RAD57
  • nucleus
  • meiotic DNA recombinase assembly
  • heteroduplex formation
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • DNA recombinase assembly
  • DNA-dependent ATPase activity
  • protein heterodimerization activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleus 3.5796E-3 5 2041 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    double-strand break repair via single-strand annealing 1.5357E-15 5 9 5 6292
    heteroduplex formation 1.1493E-12 5 6 4 6292
    double-strand break repair via synthesis-dependent strand annealing 2.6813E-12 5 7 4 6292
    non-recombinational repair 3.3913E-12 5 34 5 6292
    double-strand break repair 5.1032E-11 5 57 5 6292
    telomere maintenance via recombination 1.3927E-10 5 16 4 6292
    double-strand break repair via homologous recombination 5.5932E-10 5 22 4 6292
    recombinational repair 1.1425E-9 5 26 4 6292
    DNA recombination 1.7892E-9 5 114 5 6292
    mitotic recombination 3.1244E-9 5 33 4 6292
    DNA recombinase assembly 4.8163E-9 5 6 3 6292
    meiotic DNA recombinase assembly 4.8163E-9 5 6 3 6292
    DNA repair 2.5145E-8 5 192 5 6292
    response to DNA damage stimulus 7.125E-8 5 236 5 6292
    meiosis I 1.1405E-7 5 79 4 6292
    cellular response to stress 2.0123E-7 5 290 5 6292
    cellular response to stimulus 7.7346E-7 5 379 5 6292
    M phase of meiotic cell cycle 1.9751E-6 5 160 4 6292
    meiosis 1.9751E-6 5 160 4 6292
    meiotic cell cycle 2.1811E-6 5 164 4 6292
    protein-DNA complex assembly 2.1835E-6 5 39 3 6292
    response to stress 3.0183E-6 5 497 5 6292
    DNA metabolic process 6.8404E-6 5 585 5 6292
    anatomical structure homeostasis 2.0169E-5 5 286 4 6292
    telomere organization 2.0169E-5 5 286 4 6292
    telomere maintenance 2.0169E-5 5 286 4 6292
    M phase 2.2511E-5 5 294 4 6292
    response to stimulus 2.6437E-5 5 766 5 6292
    cell cycle phase 5.9837E-5 5 376 4 6292
    homeostatic process 8.2708E-5 5 408 4 6292
    cell cycle process 1.7059E-4 5 490 4 6292
    cell cycle 2.2393E-4 5 525 4 6292
    cellular macromolecular complex assembly 2.281E-4 5 182 3 6292
    regulation of biological quality 2.7088E-4 5 551 4 6292
    chromosome organization 2.787E-4 5 555 4 6292
    nucleic acid metabolic process 5.7208E-4 5 1415 5 6292
    cellular macromolecular complex subunit organization 6.4832E-4 5 259 3 6292
    strand invasion 7.9466E-4 5 1 1 6292
    macromolecular complex assembly 8.2425E-4 5 281 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.5045E-4 5 1566 5 6292
    cellular component organization 1.0001E-3 5 1582 5 6292
    meiotic joint molecule formation 1.5888E-3 5 2 1 6292
    macromolecular complex subunit organization 1.6626E-3 5 357 3 6292
    cellular nitrogen compound metabolic process 1.7545E-3 5 1770 5 6292
    nitrogen compound metabolic process 1.8612E-3 5 1791 5 6292
    cellular component assembly 2.072E-3 5 385 3 6292
    organelle organization 4.3919E-3 5 1127 4 6292
    biological regulation 5.8209E-3 5 1213 4 6292
    cellular macromolecule metabolic process 6.2991E-3 5 2285 5 6292
    double-strand break repair via break-induced replication 7.1338E-3 5 9 1 6292
    macromolecule metabolic process 7.2329E-3 5 2349 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 2.5968E-8 5 55 4 6292
    ATPase activity, coupled 1.4834E-6 5 149 4 6292
    recombinase activity 3.0297E-6 5 4 2 6292
    protein heterodimerization activity 3.0297E-6 5 4 2 6292
    ATPase activity 5.9889E-6 5 211 4 6292
    protein dimerization activity 7.5694E-6 5 6 2 6292
    nucleoside-triphosphatase activity 3.5215E-5 5 329 4 6292
    hydrolase activity, acting on acid anhydrides 4.658E-5 5 353 4 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.658E-5 5 353 4 6292
    pyrophosphatase activity 4.658E-5 5 353 4 6292
    hydrolase activity 1.9328E-3 5 911 4 6292
    DNA strand annealing activity 3.1756E-3 5 4 1 6292
    catalytic activity 4.6443E-3 5 2150 5 6292
    DNA topoisomerase activity 4.7604E-3 5 6 1 6292
    binding 7.4489E-3 5 1294 4 6292

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