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Protein Overview: RAD55

General Information:
Name(s) found: RAD55 / YDR076W [SGD]
Description(s) found:
Found 33 descriptions.
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  • Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 406 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IPILink to PubMed article]
    Biological Process: meiotic DNA recombinase assembly [IMPLink to PubMed article]
    heteroduplex formation [IDALink to PubMed article]
    [NOT]double-strand break repair via single-strand annealing [IMPLink to PubMed article]
    DNA recombinase assembly [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: DNA-dependent ATPase activity [ISSLink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed articleLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLGIPLSQL IVESPKPLSS GITGLDEILN LGFQARSIYE IFGPPGIGKT NFGIQLVCNS  60
   61 LEGIQQSEIN DDKILWIETF QEMPINILRE RFQKFKIVEE NVKRVRITKF GQLLYFFQNL 120
  121 FKLSQSVRYK LVIIDGFSQL VCDHLCTLSK RGGGMIDKTI HELKCRHLIL IFTVMTKYTH 180
  181 STGSTIIVLN DCMNTAFQSN EFESLEEYYE ILDDGSNFFV NSNNERRKNN VHILKSALVA 240
  241 NIAMGSKDST WEVFLRDRIG LFRDWNEQVD ETVFVKSKRV KASSSQSNEG CTTIKEMRIN 300
  301 KRNFENLRIA IVFNLHGEDR KREGRNLKRS RSSDDRNYIV KFDFDKATGQ LRDIIDLKPD 360
  361 TANIASFPTL STSSSSCSQV FNNIDSNDNP LPNAEGKEEI IYDSEG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) RAD51 RAD52 RAD54 RAD55 RAD57
    View Details Ho Y, et al. (2002) PTC3 RAD55 YHR033W
    View Details Qiu et al. (2008) RAD51 RAD54 RAD55 RAD57

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RAD55 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..262] PSI-BLAST 68.30103 RecA
    2 View Details [263..336] PSI-BLAST 68.30103 RecA
    3 View Details [337..406] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle