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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ASF1
  • chromatin assembly complex
    		•
  • histone acetylation
  • DNA replication-independent nucleosome assembly
  • chromatin silencing at silent mating-type cassette
  • nucleosome disassembly
  • chromatin silencing at telomere
  • DNA replication-dependent nucleosome assembly
    		•
  • histone binding
    		•
    HIR1
  • nucleus
  • HIR complex
  • chromosome, centromeric region
    		•
  • DNA replication-independent nucleosome assembly
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription corepressor activity
    		•
    HIR2
  • nucleus
  • HIR complex
    		•
  • DNA replication-independent nucleosome assembly
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription corepressor activity
    		•
    HPC2
  • nucleus
  • HIR complex
    		•
  • regulation of transcription involved in G1/S-phase of mitotic cell cycle
  • DNA replication-independent nucleosome assembly
  • RNA elongation from RNA polymerase II promoter
    		•
  • transcription regulator activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin assembly complex 7.5871E-12 4 12 4 6292
    HIR complex 9.6371E-10 4 5 3 6292
    nuclear part 9.4015E-4 4 1103 4 6292
    protein complex 1.0617E-3 4 1137 4 6292
    macromolecular complex 4.5471E-3 4 1635 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA replication-independent nucleosome assembly 2.2991E-13 4 6 4 6292
    DNA replication-independent nucleosome organization 2.2991E-13 4 6 4 6292
    nucleosome assembly 2.7896E-11 4 16 4 6292
    chromatin assembly 5.9409E-11 4 19 4 6292
    nucleosome organization 3.6404E-10 4 29 4 6292
    DNA packaging 5.5118E-10 4 32 4 6292
    chromatin assembly or disassembly 8.0255E-10 4 35 4 6292
    protein-DNA complex assembly 1.2607E-9 4 39 4 6292
    DNA conformation change 6.503E-9 4 58 4 6292
    cellular macromolecular complex assembly 6.7785E-7 4 182 4 6292
    RNA elongation from RNA polymerase II promoter 8.7717E-7 4 39 3 6292
    chromatin organization 1.0528E-6 4 203 4 6292
    RNA elongation 1.361E-6 4 45 3 6292
    cellular macromolecular complex subunit organization 2.8077E-6 4 259 4 6292
    macromolecular complex assembly 3.8974E-6 4 281 4 6292
    macromolecular complex subunit organization 1.02E-5 4 357 4 6292
    regulation of transcription, DNA-dependent 1.0315E-5 4 358 4 6292
    regulation of RNA metabolic process 1.0906E-5 4 363 4 6292
    regulation of transcription 1.367E-5 4 384 4 6292
    cellular component assembly 1.3814E-5 4 385 4 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.867E-5 4 415 4 6292
    regulation of nitrogen compound metabolic process 1.8852E-5 4 416 4 6292
    regulation of gene expression 2.4707E-5 4 445 4 6292
    regulation of macromolecule biosynthetic process 2.7251E-5 4 456 4 6292
    regulation of cellular biosynthetic process 3.1296E-5 4 472 4 6292
    regulation of biosynthetic process 3.1563E-5 4 473 4 6292
    regulation of macromolecule metabolic process 3.5776E-5 4 488 4 6292
    transcription, DNA-dependent 4.0396E-5 4 503 4 6292
    RNA biosynthetic process 4.2031E-5 4 508 4 6292
    regulation of primary metabolic process 4.4059E-5 4 514 4 6292
    regulation of cellular metabolic process 5.2125E-5 4 536 4 6292
    regulation of metabolic process 5.655E-5 4 547 4 6292
    transcription 5.8652E-5 4 552 4 6292
    chromosome organization 5.9941E-5 4 555 4 6292
    cellular component biogenesis 1.4687E-4 4 694 4 6292
    regulation of transcription from RNA polymerase II promoter 1.8288E-4 4 228 3 6292
    regulation of cellular process 2.5447E-4 4 796 4 6292
    regulation of biological process 2.9228E-4 4 824 4 6292
    RNA metabolic process 5.2568E-4 4 954 4 6292
    transcription from RNA polymerase II promoter 5.749E-4 4 335 3 6292
    nucleosome disassembly 6.3573E-4 4 1 1 6292
    DNA replication-dependent nucleosome assembly 6.3573E-4 4 1 1 6292
    DNA replication-dependent nucleosome organization 6.3573E-4 4 1 1 6292
    chromatin disassembly 6.3573E-4 4 1 1 6292
    protein-DNA complex disassembly 6.3573E-4 4 1 1 6292
    organelle organization 1.0248E-3 4 1127 4 6292
    cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
    macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
    biological regulation 1.3758E-3 4 1213 4 6292
    gene expression 1.7224E-3 4 1283 4 6292
    nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
    cellular biosynthetic process 3.8359E-3 4 1567 4 6292
    cellular component organization 3.9851E-3 4 1582 4 6292
    biosynthetic process 4.1907E-3 4 1602 4 6292
    cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
    nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292
    regulation of transcription involved in G1/S-phase of mitotic cell cycle 8.8726E-3 4 14 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription corepressor activity 3.6271E-5 4 16 2 6292
    transcription cofactor activity 2.3456E-4 4 40 2 6292
    transcription factor binding 2.7138E-4 4 43 2 6292
    transcription repressor activity 2.8424E-4 4 44 2 6292
    transcription regulator activity 5.9551E-4 4 339 3 6292
    protein binding 3.3984E-3 4 612 3 6292
    histone binding 8.8726E-3 4 14 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle