YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes:	Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size:	13 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
NHP6A	nuclear chromatin	chromatin remodeling chromatin organization positive regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase III promoter regulation of transcription from RNA polymerase II promoter	chromatin binding
PBP4	nucleus cytoplasm	biological_process	molecular_function
PUF4	cytoplasm	loss of chromatin silencing involved in replicative cell aging protein localization mRNA catabolic process nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	mRNA binding
RPL11B	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	ribosomal large subunit assembly translation	structural constituent of ribosome
RPL17B	ribonucleoprotein complex cytoplasm large ribosomal subunit cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPL20A		translation	structural constituent of ribosome
RPL2A, RPL2B	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	regulation of translation response to drug translation	RNA binding structural constituent of ribosome rRNA binding
RPL32	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPL36A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	RNA binding structural constituent of ribosome
RPL42B, RPL42A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	response to antibiotic response to cycloheximide translation	structural constituent of ribosome
RPL4A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPS16B, RPS16A	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm ribosome 90S preribosome intracellular	regulation of translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis translation	structural constituent of ribosome
RPS23B, RPS23A	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm small ribosomal subunit ribosome intracellular	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) regulation of translational fidelity translation	structural constituent of ribosome

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
cytosolic ribosome	3.3436E-14	13	101	9	6292
cytosolic part	1.9291E-13	13	122	9	6292
ribosomal subunit	7.9273E-12	13	183	9	6292
cytosolic large ribosomal subunit	8.211E-12	13	60	7	6292
cytosol	4.1895E-10	13	284	9	6292
ribosome	5.0523E-10	13	290	9	6292
large ribosomal subunit	6.486E-10	13	110	7	6292
ribonucleoprotein complex	8.0439E-8	13	514	9	6292
non-membrane-bounded organelle	1.1943E-6	13	959	10	6292
intracellular non-membrane-bounded organelle	1.1943E-6	13	959	10	6292
macromolecular complex	1.3229E-3	13	1635	9	6292
cytosolic small ribosomal subunit	2.6567E-3	13	38	2	6292
organelle part	3.3831E-3	13	2282	10	6292
intracellular organelle part	3.3831E-3	13	2282	10	6292
small ribosomal subunit	9.5347E-3	13	73	2	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation	1.2594E-10	13	376	10	6292
cellular macromolecule biosynthetic process	2.0887E-8	13	1187	12	6292
macromolecule biosynthetic process	2.1308E-8	13	1189	12	6292
gene expression	5.2425E-8	13	1283	12	6292
cellular biosynthetic process	5.5313E-7	13	1567	12	6292
biosynthetic process	7.1688E-7	13	1602	12	6292
cellular protein metabolic process	3.5144E-6	13	1074	10	6292
protein metabolic process	5.9807E-6	13	1136	10	6292
cellular macromolecule metabolic process	4.4721E-5	13	2285	12	6292
macromolecule metabolic process	6.1467E-5	13	2349	12	6292
regulation of translation	1.8907E-4	13	57	3	6292
posttranscriptional regulation of gene expression	2.3144E-4	13	61	3	6292
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.0349E-4	13	13	2	6292
regulation of cellular protein metabolic process	3.1959E-4	13	68	3	6292
regulation of protein metabolic process	4.1043E-4	13	74	3	6292
primary metabolic process	6.6865E-4	13	2896	12	6292
cellular metabolic process	1.1248E-3	13	3033	12	6292
regulation of gene expression	1.383E-3	13	445	5	6292
regulation of macromolecule biosynthetic process	1.5444E-3	13	456	5	6292
metabolic process	1.7612E-3	13	3157	12	6292
regulation of cellular biosynthetic process	1.804E-3	13	472	5	6292
regulation of biosynthetic process	1.8213E-3	13	473	5	6292
response to cycloalkane	2.0661E-3	13	1	1	6292
response to organic cyclic substance	2.0661E-3	13	1	1	6292
response to cycloheximide	2.0661E-3	13	1	1	6292
regulation of macromolecule metabolic process	2.095E-3	13	488	5	6292
regulation of primary metabolic process	2.6408E-3	13	514	5	6292
regulation of cellular metabolic process	3.1797E-3	13	536	5	6292
regulation of metabolic process	3.4778E-3	13	547	5	6292
response to antibiotic	6.1865E-3	13	3	1	6292
maturation of SSU-rRNA	6.3097E-3	13	59	2	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
structural constituent of ribosome	4.0059E-13	13	212	10	6292
structural molecule activity	4.4859E-11	13	339	10	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis