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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARX1
  • cytoplasm
  • nucleoplasm
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • IPI3
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • MDN1
  • nucleus
  • mitochondrion
  • nucleoplasm
  • protein complex assembly
  • rRNA processing
  • ribosomal large subunit assembly
  • ATPase activity
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NOG2
  • nucleus
  • nucleolus
  • nucleoplasm
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • GTPase activity
  • NOP15
  • nucleus
  • nucleolus
  • cytokinesis, actomyosin contractile ring assembly
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOP7
  • nucleus
  • nucleolus
  • cell proliferation
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • cell cycle
  • molecular_function
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • RIX1
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • SDA1
  • nucleus
  • ribosome biogenesis
  • traversing start control point of mitotic cell cycle
  • ribosome assembly
  • actin cytoskeleton organization
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear lumen 2.6995E-12 12 453 11 6292
    organelle lumen 1.7049E-10 12 660 11 6292
    intracellular organelle lumen 1.7049E-10 12 660 11 6292
    membrane-enclosed lumen 3.2513E-10 12 700 11 6292
    nucleolus 2.9678E-8 12 211 7 6292
    nuclear part 4.6507E-8 12 1103 11 6292
    nucleus 1.3278E-6 12 2041 12 6292
    nucleoplasm 7.781E-5 12 264 5 6292
    organelle part 1.1283E-4 12 2282 11 6292
    intracellular organelle part 1.1283E-4 12 2282 11 6292
    nuclear outer membrane 4.9621E-4 12 86 3 6292
    nuclear membrane 7.0645E-4 12 97 3 6292
    non-membrane-bounded organelle 7.3226E-4 12 959 7 6292
    intracellular non-membrane-bounded organelle 7.3226E-4 12 959 7 6292
    membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    outer membrane 4.0567E-3 12 178 3 6292
    organelle outer membrane 4.0567E-3 12 178 3 6292
    intracellular organelle 5.3355E-3 12 4070 12 6292
    organelle 5.3513E-3 12 4071 12 6292
    nuclear envelope 5.5509E-3 12 199 3 6292
    nuclear membrane-endoplasmic reticulum network 8.5044E-3 12 232 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit biogenesis 1.621E-16 12 65 9 6292
    ribosome biogenesis 6.3713E-16 12 346 12 6292
    ribonucleoprotein complex biogenesis 1.6448E-15 12 374 12 6292
    cellular component biogenesis 2.9777E-12 12 694 12 6292
    ribosome assembly 7.683E-10 12 64 6 6292
    organelle assembly 1.2234E-9 12 69 6 6292
    ribonucleoprotein complex assembly 7.1402E-9 12 92 6 6292
    cellular macromolecular complex assembly 4.3153E-7 12 182 6 6292
    cellular macromolecular complex subunit organization 3.4443E-6 12 259 6 6292
    macromolecular complex assembly 5.5394E-6 12 281 6 6292
    establishment of ribosome localization 1.3448E-5 12 26 3 6292
    ribosome localization 1.3448E-5 12 26 3 6292
    ribosomal subunit export from nucleus 1.3448E-5 12 26 3 6292
    macromolecular complex subunit organization 2.2087E-5 12 357 6 6292
    cellular component assembly 3.4027E-5 12 385 6 6292
    ribosomal large subunit assembly 5.4254E-5 12 41 3 6292
    ribosomal subunit assembly 1.3153E-4 12 55 3 6292
    establishment of organelle localization 1.3153E-4 12 55 3 6292
    organelle localization 4.7942E-4 12 85 3 6292
    nuclear export 8.419E-4 12 103 3 6292
    rRNA processing 1.5818E-3 12 128 3 6292
    nuclear transport 1.6541E-3 12 130 3 6292
    nucleocytoplasmic transport 1.6541E-3 12 130 3 6292
    rRNA metabolic process 1.9237E-3 12 137 3 6292
    actomyosin structure organization 5.7116E-3 12 3 1 6292
    cytokinesis, actomyosin contractile ring assembly 5.7116E-3 12 3 1 6292
    assembly of actomyosin apparatus involved in cell cycle cytokinesis 5.7116E-3 12 3 1 6292
    ncRNA processing 6.8876E-3 12 215 3 6292
    cell proliferation 9.5026E-3 12 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    GTPase activity 5.7327E-3 12 61 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle