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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • IMD1
    IMD3
  • cytoplasm
  • GTP biosynthetic process
  • IMP dehydrogenase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 3.4126E-7 12 34 4 6292
    90S preribosome 3.5513E-6 12 17 3 6292
    cytosolic ribosome 2.8052E-5 12 101 4 6292
    cytosolic small ribosomal subunit 4.3074E-5 12 38 3 6292
    cytosolic part 5.9058E-5 12 122 4 6292
    ribonucleoprotein complex 1.7405E-4 12 514 6 6292
    ribosomal subunit 2.8546E-4 12 183 4 6292
    small ribosomal subunit 3.0582E-4 12 73 3 6292
    cytosol 1.5085E-3 12 284 4 6292
    ribosome 1.6305E-3 12 290 4 6292
    non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    intracellular non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    nucleolus 6.5368E-3 12 211 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.0588E-8 12 376 8 6292
    gene expression 7.1736E-5 12 1283 9 6292
    cellular protein metabolic process 1.8195E-4 12 1074 8 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.571E-4 12 13 2 6292
    protein metabolic process 2.7396E-4 12 1136 8 6292
    ribosome biogenesis 2.8065E-4 12 346 5 6292
    cellular biosynthetic process 3.745E-4 12 1567 9 6292
    cellular macromolecule biosynthetic process 3.766E-4 12 1187 8 6292
    macromolecule biosynthetic process 3.8121E-4 12 1189 8 6292
    ribonucleoprotein complex biogenesis 4.0398E-4 12 374 5 6292
    biosynthetic process 4.4838E-4 12 1602 9 6292
    GTP biosynthetic process 3.811E-3 12 2 1 6292
    maturation of SSU-rRNA 5.3712E-3 12 59 2 6292
    cellular component biogenesis 6.5683E-3 12 694 5 6292
    cellular macromolecule metabolic process 7.3778E-3 12 2285 9 6292
    macromolecule metabolic process 9.0889E-3 12 2349 9 6292
    primary metabolic process 9.5102E-3 12 2896 10 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 3.0669E-8 12 212 7 6292
    structural molecule activity 7.7687E-7 12 339 7 6292
    IMP dehydrogenase activity 5.7116E-3 12 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle