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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.463361604943]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RAD18
  • nuclear chromatin
    		•
  • DNA repair
  • postreplication repair
    		•
  • ubiquitin-protein ligase activity
  • DNA-dependent ATPase activity
  • single-stranded DNA binding
    		•
    RAD5
  • nuclear chromatin
    		•
  • DNA repair
  • telomere maintenance
  • double-strand break repair
    		•
  • ATPase activity
  • single-stranded DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear chromatin 1.3278E-4 2 73 2 6292
    chromatin 1.4784E-4 2 77 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    postreplication repair 5.7138E-3 2 18 1 6292
    response to stress 6.2277E-3 2 497 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    single-stranded DNA binding 6.0632E-6 2 16 2 6292
    structure-specific DNA binding 4.7798E-5 2 44 2 6292
    ATPase activity 1.1194E-3 2 211 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle