From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.646090008862] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
FACT complex | 5.0527E-8 | 2 | 2 | 2 | 6292 |
alpha DNA polymerase:primase complex | 1.0611E-6 | 2 | 7 | 2 | 6292 |
nuclear replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
nuclear replication fork | 9.6001E-6 | 2 | 20 | 2 | 6292 |
transcription elongation factor complex | 1.2783E-5 | 2 | 23 | 2 | 6292 |
replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
nuclear chromatin | 1.3278E-4 | 2 | 73 | 2 | 6292 |
chromatin | 1.4784E-4 | 2 | 77 | 2 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
RNA elongation from RNA polymerase II promoter | 3.744E-5 | 2 | 39 | 2 | 6292 |
RNA elongation | 5.0022E-5 | 2 | 45 | 2 | 6292 |
transcription initiation from RNA polymerase II promoter | 5.4619E-5 | 2 | 47 | 2 | 6292 |
transcription initiation | 8.3521E-5 | 2 | 58 | 2 | 6292 |
protein complex assembly | 6.0304E-4 | 2 | 155 | 2 | 6292 |
protein complex biogenesis | 6.0304E-4 | 2 | 155 | 2 | 6292 |
macromolecular complex assembly | 1.9877E-3 | 2 | 281 | 2 | 6292 |
transcription from RNA polymerase II promoter | 2.8267E-3 | 2 | 335 | 2 | 6292 |
macromolecular complex subunit organization | 3.2108E-3 | 2 | 357 | 2 | 6292 |
cellular component assembly | 3.7349E-3 | 2 | 385 | 2 | 6292 |
transcription, DNA-dependent | 6.3792E-3 | 2 | 503 | 2 | 6292 |
RNA biosynthetic process | 6.5067E-3 | 2 | 508 | 2 | 6292 |
transcription | 7.6839E-3 | 2 | 552 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
RNA polymerase II transcription elongation factor activity | 4.1283E-3 | 2 | 13 | 1 | 6292 |
transcription elongation regulator activity | 6.0308E-3 | 2 | 19 | 1 | 6292 |