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Protein Overview: RRP15

General Information:
Name(s) found: RRP15 / YPR143W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Nucleolar protein, constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 250 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    processing of 27S pre-rRNA [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSKHRVDTK DKKRTRKNAE FGREKRNSGN QELSNEPEKD TIMEGDEAEE DEQNSSSDES  60
   61 SKIIDNEQSD AEEDDDEEEE DDDFPRKKKS KNSKHDDGST GFSAAVNAIL SSHLKAYDRK 120
  121 DPIMARNKKV LKQSESEKLE YKAKKALLAE KKKLLGKARK TDIIPIASGE DRSENIRKVL 180
  181 EKETALRKIA QKGAVKLFNA ILATQVKTEK EVSENLSEIK NKEEKKELIT EVSKEKFLDL 240
  241 VKAAAGSDNE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) RRP14 RRP15 SSF1 SSF2 URB1
    View Details Ho Y, et al. (2002) CKA2 CKB2 DBP10 HAS1 MAM33 NOP1 NOP7 NUG1 RPF2 RRP1 RRP15 RRP5 SPB1 SRP1 TIF6 YTM1
    View Details Qiu et al. (2008) DBP7 KRR1 NUG1 RRP15 RRP17 TMA23 YBL028C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen STE50 RRP15 1 Unpublished Fields Lab Data
    View Screen RAD51 RRP15 1 Unpublished Fields Lab Data
    View Screen UBI4 RRP15 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RRP15 Huh WK, et al. (2003)
    View Data RRP15 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..59] Pcons 1.83 Tropomyosin
    2 View Details [60..250] Pcons 1.83 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  2.00129843720424 bayes_pls_golite062009
  • ligase activity
    		•  1.98077174557863 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.862926651283562 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  0.745565725576299 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  0.667340452132993 bayes_pls_golite062009
  • binding
    		•  0.613197835889791 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  0.567749459702602 bayes_pls_golite062009
  • mRNA binding
    		•  0.45378771470672 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle